2020
The Role of Lower Extremity Amputation in Chronic Limb-Threatening Ischemia
Kim TI, Mena C, Sumpio BE. The Role of Lower Extremity Amputation in Chronic Limb-Threatening Ischemia. International Journal Of Angiology 2020, 29: 149-155. PMID: 32904807, PMCID: PMC7458760, DOI: 10.1055/s-0040-1710075.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaImproved limb salvage ratesChronic limb threatening ischemiaRole of amputationLimb salvage rateLimb threatening ischemiaLimb-threatening ischemiaPeripheral artery diseaseLower Extremity AmputationMajor amputationPrimary amputationArtery diseaseLimb salvageSalvage rateExtremity amputationImproved careLimb lossSevere formMultidisciplinary teamAmputationRevascularizationIschemiaPatientsHigh rateSalvage
2019
Infected Ischemic Foot: Investigation
Miller S, Sumpio B, Sumpio B. Infected Ischemic Foot: Investigation. 2019, 481-495. DOI: 10.1007/978-3-319-17918-6_38.Peer-Reviewed Original ResearchIschemic footAssessment of ischemiaFocused physical examDiabetic patientsLimb salvageWound infectionPhysical examAncillary testingPatient historyPathologic processesDisease resultsSeparate diagnosisDiagnostic imagingDistinct diagnosisInfectionPrimary locationHealing capacityDistal partDiagnosisFootLaboratory testingCommon occurrenceUlcerationIschemiaPatientsNewer Techniques for Assessment of Foot Perfusion
Sumpio B, Miller S, Benitez E, Sumpio B. Newer Techniques for Assessment of Foot Perfusion. 2019, 243-257. DOI: 10.1007/978-3-319-17918-6_20.Peer-Reviewed Original ResearchCritical limb ischemiaPeripheral arterial diseaseLaser Doppler flowmetryMagnetic resonance angiographyDigital subtraction angiographyFoot perfusionLimb ischemiaLimb salvageRevascularization therapyArterial diseaseTranscutaneous oximetryFluorescent angiographyTomographic angiographyVascular specialistsDoppler flowmetryAtherosclerotic lesionsDisease processClinical practiceResonance angiographyPatient careAngiographySubtraction angiographyDiagnostic imagingNoninvasive imagingGold standardIntroduction to the Neuropathic Foot: Limb Salvage Pathway and Algorithm
Petrova N, Sumpio B, Edmonds M. Introduction to the Neuropathic Foot: Limb Salvage Pathway and Algorithm. 2019, 25-29. DOI: 10.1007/978-3-319-17918-6_2.Peer-Reviewed Original ResearchNeuropathic footImpact of neuropathySoft tissue advancementSplit skin graftSoft tissue coverageLocal rotational flapFree tissue transferPlatelet-rich plasmaAdvanced wound therapiesMatrix metalloproteinase inhibitorsLimb salvageCell-based therapiesSkin graftsTissue coverageWound therapyRotational flapTissue transferRecombinant growth factorsRich plasmaGrowth factorMetalloproteinase inhibitorsTissue advancementSenescent cellsTherapyAcellular matrixRole of Angiosomes in Guiding Target Intervention for Open Procedures
Citoni G, Taurino M, Sumpio B. Role of Angiosomes in Guiding Target Intervention for Open Procedures. 2019, 323-332. DOI: 10.1007/978-3-319-17918-6_25.Peer-Reviewed Original ResearchPeripheral arterial diseaseCritical limb ischemiaTarget vesselExtensive tissue lossQuality of lifeIschemic tissue lesionsLimb ischemiaLimb salvageArterial diseaseSevere progressionProlonging survivalOpen procedureLeg amputationPedal archTissue lesionsTissue lossIndividualized approachPatientsTarget interventionsAnatomic conceptsRevascularizationDiseaseInterventionBest vesselVessels
2014
New advances in limb salvage.
Chin JA, Sumpio BE. New advances in limb salvage. Surgical Technology Online 2014, 25: 212-6. PMID: 25433346.Peer-Reviewed Original ResearchCritical limb ischemiaLimb salvageDistal vein patchType of therapyDrug-eluting stentsQuality of lifeEndovascular therapyLimb ischemiaPatient mortalityVein patchPoor outcomeEndovascular interventionTreatment optionsMorbid diseaseVascular surgerySurgical techniqueLimb lossHealthcare costsEpidemiologic problemNew advancesTherapySalvageInterventionFurther researchContemporary assessment of foot perfusion in patients with critical limb ischemia
Benitez E, Sumpio BJ, Chin J, Sumpio BE. Contemporary assessment of foot perfusion in patients with critical limb ischemia. Seminars In Vascular Surgery 2014, 27: 3-15. PMID: 25812754, DOI: 10.1053/j.semvascsurg.2014.12.001.Peer-Reviewed Original ResearchConceptsCritical limb ischemiaLimb ischemiaFoot perfusionLower extremity perfusionPeripheral arterial diseaseTranscutaneous oxygen monitoringRevascularization techniquesArterial diseaseFoot ulcerationLimb salvageRevascularization therapyFluorescent angiographyPatient outcomesEndovascular proceduresDisease processPatient careIschemiaDiagnostic imagingPatientsPerfusionImaging modalitiesLaser DopplerOxygen monitoringPlanning interventionsModalities
2012
Contemporary Evaluation and Management of the Diabetic Foot
Sumpio BE. Contemporary Evaluation and Management of the Diabetic Foot. Scientifica 2012, 2012: 435487. PMID: 24278695, PMCID: PMC3820495, DOI: 10.6064/2012/435487.Peer-Reviewed Original ResearchDiabetic footNegative pressure wound therapyMajor public health issueMainstay of therapyDiabetic foot diseaseGood functional outcomeHospitalization of patientsHealth care workersPressure wound therapyTreatment of infectionsMoist wound carePublic health issueComplex clinical problemWidespread clinical practiceAbnormal foot structureAggressive debridementSuperimposed infectionFrequent debridementLimb salvageFoot ulcersChronic inflammationCostly complicationFunctional outcomeFoot problemsIschemic limbsDiabetic Foot Ulceration and Management
Blume P, Jain A, Sumpio B. Diabetic Foot Ulceration and Management. Contemporary Diabetes 2012, 63-91. DOI: 10.1007/978-1-62703-158-5_6.Peer-Reviewed Original ResearchFoot ulcersMajor public health issueGrowth factorDiabetic foot diseaseDiabetic foot ulcerationHospitalization of patientsGood clinical careTreatment of infectionsMoist wound carePublic health issueComplex clinical problemWidespread clinical practiceAbnormal foot structureAdjuvant therapySuperimposed infectionFoot ulcerationFrequent debridementLimb salvagePathophysiologic mechanismsChronic inflammationDiabetic footCostly complicationFoot problemsIschemic limbsClinical trials
2007
Predictors for the Healing of Transmetatarsal Amputations: Retrospective Study of 91 Amputations
Blume P, Salonga C, Garbalosa J, Pierre-Paul D, Key J, Gahtan V, Sumpio BE. Predictors for the Healing of Transmetatarsal Amputations: Retrospective Study of 91 Amputations. Vascular 2007, 15: 126-133. PMID: 17573017, DOI: 10.2310/6670.2007.00035.Peer-Reviewed Original Research
2004
The Multidisciplinary Approach to Limb Salvage
Sumpio BE, Aruny J, Blume PA. The Multidisciplinary Approach to Limb Salvage. Acta Chirurgica Belgica 2004, 104: 647-653. PMID: 15663269, DOI: 10.1080/00015458.2004.11679637.Peer-Reviewed Original ResearchConceptsNon-diabetic patientsPrimary care physiciansMultidisciplinary approachLower extremity woundsComprehensive treatment protocolAggressive treatmentConsiderable morbidityLimb salvageCare physiciansMetabolic derangementsVascular diseaseClinical trialsExtremity woundsVascular surgeonsTreatment protocolLower limbsFoot abnormalitiesPlastic surgeonsCareful assessmentPatientsPodiatristsPhysiciansSurgeonsMorbidityUlceration
2003
Vascular evaluation and arterial reconstruction of the diabetic foot
Sumpio BE, Lee T, Blume PA. Vascular evaluation and arterial reconstruction of the diabetic foot. Clinics In Podiatric Medicine And Surgery 2003, 20: 689-708. PMID: 14636033, DOI: 10.1016/s0891-8422(03)00088-0.Peer-Reviewed Original ResearchConceptsInfected footDiabetic footLimb salvageNon-invasive vascular studiesCardiovascular risk factor managementAggressive multidisciplinary approachAggressive surgical drainagePalpable pedal pulsesLimb-threatening ischemiaPeripheral vascular diseaseRisk factor managementLower extremity revascularizationStandard clinical evaluationPrimary care providersCumulative limb salvageEvidence of infectionHigh-risk groupBlood glucose controlHigh-risk populationComplex clinical problemAbsent pulsesAggressive drainageIschemic ulcerationPedal bypassPedal pulses
2000
Gender does not impact infrainguinal vein bypass graft outcome
Frangos S, Karimi S, Kerstein M, Harpavat M, Sumpio B, Roberts A, Gahtan V. Gender does not impact infrainguinal vein bypass graft outcome. Surgery 2000, 127: 679-686. PMID: 10840364, DOI: 10.1067/msy.2000.105859.Peer-Reviewed Original ResearchConceptsGraft patencySurvival rateMultivariate analysisInfrainguinal vein bypass graftsCox proportional hazards modelInfrainguinal occlusive diseaseLimb salvage rateVein bypass graftsBypass graft operationsProportional hazards modelLife-table analysisInfrainguinal vein bypassPercentage of womenMajor amputationGraft outcomePostoperative complicationsIncisional complicationsOcclusive diseasePostoperative outcomesLimb salvageRenal diseaseBypass graftPatient selectionVein graftsMorbidity rate