2023
Premature atherosclerosis: A review of current literature
Neifert A, Su D, Chaar C, Sumpio B. Premature atherosclerosis: A review of current literature. JVS-Vascular Insights 2023, 1: 100013. DOI: 10.1016/j.jvsvi.2023.100013.Peer-Reviewed Original ResearchRisk factorsAtherosclerotic diseaseClinical manifestationsGenetic predispositionTraditional atherosclerotic risk factorsHuman immunodeficiency virus (HIV) infectionNontraditional risk factorsActive antiretroviral therapyAtherosclerotic risk factorsImmunodeficiency virus infectionPeripheral arterial diseaseCerebral vascular diseasePremature atherosclerotic diseaseUnique risk factorsRecreational substance useAntiretroviral therapyAutoimmune conditionsDisease-associated lossMetabolic syndromeArterial diseasePremature atherosclerosisLipid derangementsMyocardial infarctionVascular diseaseVirus infection
2016
Systemic and cell-specific mechanisms of vasculopathy induced by human immunodeficiency virus and highly active antiretroviral therapy
Haser GC, Sumpio B. Systemic and cell-specific mechanisms of vasculopathy induced by human immunodeficiency virus and highly active antiretroviral therapy. Journal Of Vascular Surgery 2016, 65: 849-859. PMID: 26994951, DOI: 10.1016/j.jvs.2016.01.036.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusActive antiretroviral therapySmooth muscle cellsAntiretroviral therapyHIV patientsImmunodeficiency virusTraditional cardiovascular risk factorsMuscle cellsEndothelial cellsCardiovascular risk factorsChronic immune activationSerious cardiovascular eventsDevelopment of atherosclerosisVascular systemCardiovascular eventsVascular complicationsHIV medicationsChronic inflammationImmune activationMyocardial infarctionRisk factorsCell-specific mechanismsGeneral populationCholesterol metabolismCardiovascular pathology