2024
Impact of concomitant surgical interventions on outcomes of septal myectomy in obstructive hypertrophic cardiomyopathy
Altibi A, Sapru A, Ghanem F, Zhao Y, Alani A, Cigarroa J, Nazer B, Song H, Masri A. Impact of concomitant surgical interventions on outcomes of septal myectomy in obstructive hypertrophic cardiomyopathy. International Journal Of Cardiology 2024, 400: 131790. PMID: 38242508, DOI: 10.1016/j.ijcard.2024.131790.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiomyopathy, HypertrophicCoronary Artery BypassHeart Valve Prosthesis ImplantationHospital MortalityHumansTreatment OutcomeUnited StatesConceptsObstructive hypertrophic cardiomyopathyMitral valve replacementCoronary artery bypass graftingConcomitant surgical interventionIn-hospital mortalitySeptal myectomyAdverse in-hospital eventsIn-hospital eventsSurgical interventionMV repairValve replacementHypertrophic cardiomyopathyOutcomes of septal myectomyAssociated with increased in-hospital mortalityOutcomes of patientsAortic valve replacementIn-hospital adverse eventsAdverse clinical eventsIsolated SMArtery bypass graftingIn-hospital deathNational Readmission DatabaseSymptomatic patientsMedical therapyAdverse events
2023
Hospital Procedural Volume and Clinical Outcomes Following Septal Reduction Therapy in Obstructive Hypertrophic Cardiomyopathy
Altibi A, Ghanem F, Zhao Y, Elman M, Cigarroa J, Nazer B, Song H, Masri A. Hospital Procedural Volume and Clinical Outcomes Following Septal Reduction Therapy in Obstructive Hypertrophic Cardiomyopathy. Journal Of The American Heart Association 2023, 12: e028693. PMID: 37183831, PMCID: PMC10227305, DOI: 10.1161/jaha.122.028693.Peer-Reviewed Original ResearchMeSH KeywordsCardiomyopathy, HypertrophicEthanolHeart SeptumHospital MortalityHospitals, High-VolumeHumansTreatment OutcomeUnited StatesConceptsAlcohol septal ablationSeptal reduction therapyObstructive hypertrophic cardiomyopathyIn-hospital mortalitySeptal ablationSeptal myectomyHypertrophic cardiomyopathyReduction therapyVolume-outcome relationshipVolume tertilesInverse volume-outcome relationshipPost-SMProcedure volumeIncidence of in-hospital deathAdverse in-hospital eventsIn-hospital eventsIn-hospital deathNational Readmission DatabaseHigh-volume hospitalsHospital procedure volumeAnnual procedure volumeClinical outcomesContemporary outcomesReadmissions DatabaseHospital volumeBaseline and Longitudinal Imaging of Hypertrophic Cardiomyopathy in the Era of Emerging Therapeutics
Altibi A, Alani A, Zhao Y, Masri A. Baseline and Longitudinal Imaging of Hypertrophic Cardiomyopathy in the Era of Emerging Therapeutics. Current Cardiology Reports 2023, 25: 583-595. PMID: 37103749, DOI: 10.1007/s11886-023-01883-w.Peer-Reviewed Original ResearchMeSH KeywordsCardiac MyosinsCardiomyopathy, HypertrophicEchocardiographyHeartHumansMagnetic Resonance ImagingConceptsCardiac myosin inhibitorCardiac magnetic resonance imagingHypertrophic cardiomyopathyCare of patientsClinical trialsPathophysiology of hypertrophic cardiomyopathyCardiac magnetic resonanceNew drug therapiesHypertrophic cardiomyopathy diagnosisActin-myosin cross-bridgesLongitudinal imagingMagnetic resonance imagingMyosin inhibitorTherapeutic optionsAbstract PurposeDrug therapyOral moleculesLongitudinal imaging modalityCardiomyopathyPatientsMonitoring patientsImaging modalitiesResonance imagingInvestigate new drug therapiesSarcomere level