2024
Retinal integrity in human babesiosis: a pilot study
Dionne E, Adelman R, Cekic O, Golden M, Moffarah A, Krause P, Farhadian S. Retinal integrity in human babesiosis: a pilot study. BMC Ophthalmology 2024, 24: 310. PMID: 39048971, PMCID: PMC11267664, DOI: 10.1186/s12886-024-03568-6.Peer-Reviewed Original ResearchConceptsEvidence of retinopathyNo study patientRetina of patientsCohort of patientsAbnormal vessel formationComplication of babesiosisRetinal tearsRetinal inflammationRetinal eye examResultsTen patientsRetinal integrityRetinal examinationRetinal bleedingIndirect ophthalmoscopeRetinal abnormalitiesStudy patientsChart reviewCase reportEye examPilot studyPatientsAnimal studiesSmall studyClinical informationHuman babesiosis
2020
VISUAL OUTCOME OF EARLY VITRECTOMY AND INTRAVITREAL ANTIBIOTICS IN ACUTE POSTSURGICAL AND POSTINTRAVITREAL INJECTION ENDOPHTHALMITIS: European Vitreo-Retinal Society Endophthalmitis Study Report Two.
Soliman MK, Gini G, Kuhn F, Parolini B, Ozdek S, Adelman RA, Sallam AB. VISUAL OUTCOME OF EARLY VITRECTOMY AND INTRAVITREAL ANTIBIOTICS IN ACUTE POSTSURGICAL AND POSTINTRAVITREAL INJECTION ENDOPHTHALMITIS: European Vitreo-Retinal Society Endophthalmitis Study Report Two. Retina 2020, 41: 423-430. PMID: 32467482, DOI: 10.1097/iae.0000000000002856.Peer-Reviewed Original ResearchConceptsIntravitreal antibioticsPPV groupEarly PPVVisual outcomeRetinal detachmentPostintravitreal injection endophthalmitisRetrospective multicenter cohortFinal visual acuityWeeks of presentationDays of presentationMethod of treatmentEarly vitrectomyMulticenter cohortIntravitreal injectionPlana vitrectomyRetina specialistsVisual acuityMean ageIntraocular proceduresEndophthalmitisSimilar outcomesLight perceptionEyesVitrectomyOutcomesNational Trends in the United States Eye Care Workforce from 1995 to 2017
Feng PW, Ahluwalia A, Feng H, Adelman RA. National Trends in the United States Eye Care Workforce from 1995 to 2017. American Journal Of Ophthalmology 2020, 218: 128-135. PMID: 32445703, DOI: 10.1016/j.ajo.2020.05.018.Peer-Reviewed Original ResearchConceptsEye care workforceOphthalmologist densityYears of ageRural countiesEye care providersArea Health Resource FileCare workforceCross-sectional studyHealth care infrastructureRatio of ophthalmologistsMAIN OUTCOMECare providersMean annual increaseOphthalmologistsNumber of providersOptometristsCare infrastructureHealth insuranceResource FileYoung ophthalmologistsNational trendsCounty characteristicsGreater proportionAgeMetropolitan counties
2019
Idiopathic Macular Hole Preferred Practice Pattern®
Flaxel CJ, Adelman RA, Bailey ST, Fawzi A, Lim JI, Vemulakonda GA, Ying GS. Idiopathic Macular Hole Preferred Practice Pattern®. Ophthalmology 2019, 127: p184-p222. PMID: 31757499, DOI: 10.1016/j.ophtha.2019.09.026.Peer-Reviewed Original ResearchPanretinal Photocoagulation along the Long Ciliary Nerve in Diabetic Retinopathy
Lu AJ, Freedman IG, Shakir O, Adelman RA, Del Priore LV. Panretinal Photocoagulation along the Long Ciliary Nerve in Diabetic Retinopathy. Ophthalmology Retina 2019, 3: 1105-1107. PMID: 31519540, DOI: 10.1016/j.oret.2019.07.002.Peer-Reviewed Original ResearchInternational Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis European Vitreo-Retinal Society Endophthalmitis Study Report 1
Soliman MK, Gini G, Kuhn F, Iros M, Parolini B, Ozdek S, Michalewska Z, Bopp S, Adelman RA, Sallam AB, Group E, Kardaszewska A, Zindamoyen A, Banker A, Serhiienko A, Loo A, Meireles A, Aydin B, Luebke B, Özmen C, Odrobina D, Bertelli E, Unsal E, Kenneth F, Becquet F, Hamon F, Pellegrini G, Tosi G, Donvito G, Khaqan H, Badat I, Fiser I, Michalewski J, Le Rouic J, Nawrocki J, Zarallo-Gallardo J, Lee J, Boninska K, Nowomiejska K, Dziegielewski K, Arrevola L, Lytvynchuk L, Elshafei M, Pietras-Trzpiel M, Irós M, Detjen M, Iglicki M, Badino M, Angelina M, Gavura M, Hasanreisoğlu M, Karadaş M, Atienza N, Acar N, Okonkwo O, Miesbauer P, Malgorzata P, Velez-Montoya R, Robert R, Frisina R, Soyeur R, Rejdak R, Giannini R, Mittal S, Saidkasimova S, Abdulsalam S, Cisiecki S, Rusnak S, Teoh S, Teixeira S, Altan T, Schrader W, Kapran Z, Aktas Z, Szijártó Z. International Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis European Vitreo-Retinal Society Endophthalmitis Study Report 1. Ophthalmology Retina 2019, 3: 461-467. PMID: 31043364, DOI: 10.1016/j.oret.2019.03.009.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiogenesis InhibitorsAnti-Bacterial AgentsAntibiotic ProphylaxisCataract ExtractionDisease ManagementEndophthalmitisEuropeEye Infections, BacterialFemaleFollow-Up StudiesHumansIncidenceIntravitreal InjectionsMaleMiddle AgedOphthalmologyPractice Guidelines as TopicRetrospective StudiesSocieties, MedicalSurgical Wound InfectionVitrectomyConceptsEarly pars plana vitrectomyPars plana vitrectomyIntravitreal injectionIntravitreal antibioticsAcute endophthalmitisPlana vitrectomyIntraocular surgeryCataract surgeryPractice patternsAbsence of endophthalmitisSecond intravitreal injectionSecondary lens implantationProportion of eyesInternational practice patternsAcute postoperativeSystemic steroidsIntravitreal steroidsLens implantationAdjunctive therapySystemic antibioticsPostinjection endophthalmitisMulticenter studyRetina specialistsTherapeutic regimensVitreous opacification
2017
Vitrectomy in the management of diabetic macular edema in treatment-naïve patients
Michalewska Z, Stewart MW, Landers MB, Bednarski M, Adelman RA, Nawrocki J. Vitrectomy in the management of diabetic macular edema in treatment-naïve patients. Canadian Journal Of Ophthalmology 2017, 53: 402-407. PMID: 30119796, DOI: 10.1016/j.jcjo.2017.10.011.Peer-Reviewed Original ResearchConceptsTreatment-naïve diabetic macular edemaDiabetic macular edemaCentral retinal thicknessPars plana vitrectomyMacular edemaVisual acuityPlana vitrectomyMean central retinal thicknessDuration of diabetesProspective randomized trialsTreatment-naïve patientsInitial visual acuityVisual acuity changesPrimary outcome measureEfficacy of vitrectomyElectronic medical recordsEarly vitrectomyIntravitreal bevacizumabFinal BCVAMean BCVAPrimary endpointRetinal thicknessConsecutive patientsRandomized trialsRetrospective studyASSOCIATION BETWEEN THE VITREOMACULAR INTERFACE AND OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS IN WET AGE-RELATED MACULAR DEGENERATION
Ashraf M, Souka A, Adelman RA. ASSOCIATION BETWEEN THE VITREOMACULAR INTERFACE AND OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS IN WET AGE-RELATED MACULAR DEGENERATION. Retina 2017, 37: 1738-1745. PMID: 28005632, DOI: 10.1097/iae.0000000000001423.Peer-Reviewed Original ResearchConceptsType 1 choroidal neovascularizationChoroidal thicknessChoroidal neovascularizationWet AMDVitreomacular adhesionDry AMDVitreomacular interfaceMacular degenerationRetrospective observational cross-sectional studyOptical coherence tomography examinationObservational cross-sectional studyAge-related macular degenerationType of CNVPaired-eye studyMean choroidal thicknessCross-sectional studySignificant differencesOptical coherence tomographyWet AgeSubgroup analysisTomography examinationHeidelberg SpectralisPatientsCoherence tomographyDegeneration characteristic
2016
Trends of Anti-Vascular Endothelial Growth Factor Use in Ophthalmology Among Privately Insured and Medicare Advantage Patients
Parikh R, Ross JS, Sangaralingham LR, Adelman RA, Shah ND, Barkmeier AJ. Trends of Anti-Vascular Endothelial Growth Factor Use in Ophthalmology Among Privately Insured and Medicare Advantage Patients. Ophthalmology 2016, 124: 352-358. PMID: 27890437, DOI: 10.1016/j.ophtha.2016.10.036.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngiogenesis InhibitorsBevacizumabCohort StudiesDatabases, FactualDiabetic RetinopathyDrug UtilizationFemaleHumansInsurance, HealthIntravitreal InjectionsMacular DegenerationMaleMedicare Part CMiddle AgedOphthalmologyPrivate SectorRanibizumabReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetinal Vein OcclusionRetrospective StudiesUnited StatesVascular Endothelial Growth Factor AYoung AdultConceptsAge-related macular degenerationDiabetic retinal diseaseAnti-VEGF injectionsIntravitreal anti-VEGF injectionsRetinal vein occlusionAdministrative claims dataRetinal diseasesOphthalmic diseasesVein occlusionClaims dataUse of bevacizumabCurrent Procedural Terminology codesPatients 18 yearsRetrospective cohort studyMedicare Advantage patientsOptumLabs Data WarehouseDrug Administration approvalProcedural Terminology codesGrowth factor useRanibizumab useBevacizumab useAvailable medicationsCohort studyMedication useCommon medicationsHyperacuity Exam Screens for Choroidal Neovascularization in Age-Related Macular Degeneration on a Mobile Device.
Chen JS, Adelman RA. Hyperacuity Exam Screens for Choroidal Neovascularization in Age-Related Macular Degeneration on a Mobile Device. Ophthalmic Surgery Lasers And Imaging Retina 2016, 47: 708-15. PMID: 27548447, DOI: 10.3928/23258160-20160808-03.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChoroidChoroidal NeovascularizationComputers, HandheldCross-Sectional StudiesEquipment DesignFemaleFluorescein AngiographyFundus OculiHumansMacular DegenerationMaleMiddle AgedMobile ApplicationsMonitoring, PhysiologicReproducibility of ResultsTomography, Optical CoherenceVisual AcuityConceptsAge-related macular degenerationChoroidal neovascularizationMacular degenerationSpectral-domain optical coherence tomographySingle-center studyProgression of diseaseOptical coherence tomographyChart reviewTimely treatmentPatientsCoherence tomographyNeovascularizationPatient informationSame dayTreatmentPotential screenFurther dataHuman Research Protection ProgramDegenerationSubspecialistsDiseaseProgression
2015
CHOROIDAL THICKNESS MEASURED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY BEFORE AND AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING FOR IDIOPATHIC EPIRETINAL MEMBRANES
Michalewska Z, Michalewski J, Adelman RA, Zawilak E, Nawrocki J. CHOROIDAL THICKNESS MEASURED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY BEFORE AND AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING FOR IDIOPATHIC EPIRETINAL MEMBRANES. Retina 2015, 35: 487-491. PMID: 25322467, DOI: 10.1097/iae.0000000000000350.Peer-Reviewed Original ResearchConceptsIdiopathic epiretinal membraneOuter choroidoscleral boundaryChoroidal thicknessFellow eyesEpiretinal membraneMembrane peelingINTERNAL LIMITING MEMBRANE PEELINGPatient's fellow eyeUnaffected fellow eyesPars plana vitrectomyChoroidal thickness measurementsRetinal pigment epitheliumSource optical coherence tomographyOptical coherence tomographySuprachoroidal layerOperated eyesRetinal arteryPlana vitrectomyProspective studyERM removalPigment epitheliumHyperreflective bandSource optical coherence tomography imagesCoherence tomographySuprachoroidal space
2013
Prevalence of Ocular Manifestations of HIV/AIDS in the Highly Active Antiretroviral Therapy (HAART) Era: A Different Spectrum in Central South China
Luo J, Jing D, Kozak I, Huiming Z, Siying C, Yezhen Y, xin Q, Luosheng T, Adelman RA, Forster SH. Prevalence of Ocular Manifestations of HIV/AIDS in the Highly Active Antiretroviral Therapy (HAART) Era: A Different Spectrum in Central South China. Ophthalmic Epidemiology 2013, 20: 170-175. PMID: 23713918, DOI: 10.3109/09286586.2013.789530.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAntiretroviral Therapy, Highly ActiveAsian PeopleCD4 Lymphocyte CountCD4-Positive T-LymphocytesChildChinaCross-Sectional StudiesCytomegalovirus RetinitisEye Infections, ViralFemaleHIV InfectionsHumansMaleMiddle AgedPrevalenceRetinal DiseasesRisk FactorsVisual AcuityYoung AdultConceptsHIV/AIDSOcular manifestationsActive antiretroviral therapy (HAART) eraHuman immunodeficiency virus/Antiretroviral therapy eraActive antiretroviral therapyRoutine ophthalmic examinationEra of HAARTPrevalence of HIVCross-sectional studyHIV retinopathyTherapy eraAntiretroviral therapyCommon HIVCytomegalovirus retinitisOcular complicationsOcular examinationOcular findingsImmunodeficiency syndromeOcular lesionsOphthalmic examinationVirus/Epidemiologic studiesHigh riskOcular diseases
2012
ACUTE SYPHILITIC POSTERIOR PLACOID CHORIORETINITIS
Eandi CM, Neri P, Adelman RA, Yannuzzi LA, Cunningham ET. ACUTE SYPHILITIC POSTERIOR PLACOID CHORIORETINITIS. Retina 2012, 32: 1915-1941. PMID: 22863970, DOI: 10.1097/iae.0b013e31825f3851.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAnti-Bacterial AgentsCD4 Lymphocyte CountChorioretinitisColoring AgentsDrug Therapy, CombinationEye Infections, BacterialFemaleFluorescein AngiographyFluorescent Treponemal Antibody-Absorption TestGlucocorticoidsHIV SeropositivityHumansIndocyanine GreenInfusions, IntravenousMaleMiddle AgedPenicillin GRetrospective StudiesSyphilisTomography, Optical CoherenceVisual AcuityConceptsAcute syphilitic posterior placoid chorioretinitisPosterior placoid chorioretinitisCD4 cell countCells/μLAntibiotic therapyAngiographic featuresFluorescein angiographyPositive venereal disease research laboratoryCell countHuman immunodeficiency virus (HIV) coinfectionMedian CD4 cell countRapid plasma regain titerRecent CD4 cell countVenereal Disease Research LaboratoryFluorescent treponemal antibody absorptionEvidence of neurosyphilisMulticenter chart reviewOuter retinal lesionsImmunodeficiency virus coinfectionAppropriate antibiotic therapyPosterior segment examinationSeries of patientsHuman immunodeficiency virusPositive serologic testsRed-free photographsIntravitreal Ranibizumab for Treatment of Choroidal Neovascularization Secondary to Angioid Streaks in Pseudoxanthoma Elasticum: Five-year Follow-up
Zebardast N, Adelman RA. Intravitreal Ranibizumab for Treatment of Choroidal Neovascularization Secondary to Angioid Streaks in Pseudoxanthoma Elasticum: Five-year Follow-up. Seminars In Ophthalmology 2012, 27: 61-64. PMID: 22784267, DOI: 10.3109/08820538.2012.680644.Peer-Reviewed Original ResearchConceptsChoroidal neovascularizationOptical coherence tomographyPseudoxanthoma elasticumFluorescein angiographyNeovascular activityTreatment of CNVIntravitreal ranibizumab injectionsFive yearsMacular choroidal neovascularizationLong-term effectivenessOCT evidenceIntravitreal ranibizumabRanibizumab injectionsRanibizumab therapyAffected eyeIntraretinal fluidVisual acuityFluorescein leakageAngioid streaksScar formationInitial injectionCoherence tomographyRanibizumabInjectionNeovascularizationEffects of Music Therapy on Intravitreal Injections: A Randomized Clinical Trial
Chen X, Seth RK, Rao VS, Huang JJ, Adelman RA. Effects of Music Therapy on Intravitreal Injections: A Randomized Clinical Trial. Journal Of Ocular Pharmacology And Therapeutics 2012, 28: 414-419. PMID: 22506884, DOI: 10.1089/jop.2011.0257.Peer-Reviewed Original ResearchConceptsMusic therapy groupIntravitreal injectionTherapy groupControl groupOutpatient settingClinical trialsMusic therapyFuture injectionsRandomized clinical trialsMain outcome measuresPost-procedure questionnaireSpielberger State-Trait Anxiety InventorySTAI-S scoresState-Trait Anxiety InventoryTrait Anxiety InventoryRetina clinicMost patientsPain QuestionnaireSafe interventionSubjective painOutcome measuresPatientsPainTherapyGreater decreaseIs Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic Neuropathy?
Prescott CR, Sklar CA, Lesser RL, Adelman RA. Is Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic Neuropathy? Journal Of Neuro-Ophthalmology 2012, 32: 51-53. PMID: 22269947, DOI: 10.1097/wno.0b013e318240596e.Peer-Reviewed Original ResearchConceptsNonarteritic anterior ischemic optic neuropathyAnterior ischemic optic neuropathyIschemic optic neuropathyVisual acuityIntravitreal bevacizumabOptic neuropathyTreatment optionsIntravitreal bevacizumab injectionEffective treatment optionVisual field defectsBevacizumab injectionFellow eyesClinical outcomesRetrospective studyTreatment modalitiesNatural courseField defectsPatientsDecreased acuitySmall seriesAcuityBevacizumabProfound lossVisual fieldNeuropathy
2011
Proliferation of the ciliary epithelium with retinal neuronal and photoreceptor cell differentiation in human eyes with retinal detachment and proliferative vitreoretinopathy
Ducournau Y, Boscher C, Adelman RA, Guillaubey C, Schmidt-Morand D, Mosnier JF, Ducournau D. Proliferation of the ciliary epithelium with retinal neuronal and photoreceptor cell differentiation in human eyes with retinal detachment and proliferative vitreoretinopathy. Graefe's Archive For Clinical And Experimental Ophthalmology 2011, 250: 409-423. PMID: 21932075, DOI: 10.1007/s00417-011-1797-3.Peer-Reviewed Original ResearchMeSH KeywordsAC133 AntigenAdultAntigens, CDCell DifferentiationCell MovementCell ProliferationCiliary BodyErbB ReceptorsFemaleGlial Fibrillary Acidic ProteinGlycoproteinsHumansImmunoenzyme TechniquesKi-67 AntigenMaleMiddle AgedParaffin EmbeddingPeptidesPhosphopyruvate HydratasePhotoreceptor Cells, VertebratePigment Epithelium of EyeRetinal DetachmentRetinal NeuronsRhodopsinVitreoretinopathy, ProliferativeConceptsAnterior proliferative vitreoretinopathyRetinal detachmentAdult human eyeProliferative vitreoretinopathyCiliary bodyRetinal progenitor cellsControl eyesAdult ciliary bodyCE cellsMethodsThe present studyHuman eyeRetinal transplantationEndoscopic evaluationGFAP stainingCiliary epithelial cellsPhotoreceptor lineageOrbital tumorsVitreous baseNormal eyesDetached retinaStrong stainingGlial formationCiliary epitheliumConclusionsOur observationsDonor cellsThe Treatment of Recurrent Central Serous Chorioretinopathy with Intravitreal Bevacizumab
Lee ST, Adelman RA. The Treatment of Recurrent Central Serous Chorioretinopathy with Intravitreal Bevacizumab. Journal Of Ocular Pharmacology And Therapeutics 2011, 27: 611-614. PMID: 21810026, DOI: 10.1089/jop.2011.0045.Peer-Reviewed Original ResearchConceptsRecurrent central serous chorioretinopathyMean central macular thicknessCentral macular thicknessCentral serous chorioretinopathyPreinjection visual acuityVisual acuityOptical coherence tomographyIntravitreal bevacizumabSerous chorioretinopathyTreatment optionsLow-risk treatment optionYale Eye CenterIntravitreal bevacizumab injectionRetrospective case seriesEffective treatment optionLong-term efficacySub-retinal fluidNumber of injectionsFluorescein angiography imagingBevacizumab injectionRecurrent diseaseMacular thicknessMonth 3Month 6Case series
2009
A study of macular hole formation by serial spectral optical coherence tomography
Michalewska Z, Michalewski J, Sikorski BL, Kałużny J, Wojtkowski M, Adelman RA, Nawrocki J. A study of macular hole formation by serial spectral optical coherence tomography. Clinical And Experimental Ophthalmology 2009, 37: 373-383. PMID: 19594564, DOI: 10.1111/j.1442-9071.2009.02041.x.Peer-Reviewed Original Research
2008
Sympathetic ophthalmia
Castiblanco CP, Adelman RA. Sympathetic ophthalmia. Graefe's Archive For Clinical And Experimental Ophthalmology 2008, 247: 289. PMID: 18795315, DOI: 10.1007/s00417-008-0939-8.Peer-Reviewed Original ResearchConceptsSympathetic ophthalmiaSympathizing eyeVisual acuityOcular surgeryRisk factorsVitreoretinal surgeryFavorable visual outcomeFinal visual acuitySystemic corticosteroid therapyCurrent medical managementPars plana vitrectomyCorticosteroid therapyOcular antigensGranulomatous uveitisVisual prognosisMost patientsOcular traumaPatient demographicsVisual outcomeFellow eyesClinical presentationMedical managementPlana vitrectomyHypersensitivity reactionsCase report