Inhibition of Na(+)-K(+)-ATPase activates Na(+)-K(+)-2Cl- cotransporter activity in cultured ciliary epithelium
Dong J, Delamere N, Coca-Prados M. Inhibition of Na(+)-K(+)-ATPase activates Na(+)-K(+)-2Cl- cotransporter activity in cultured ciliary epithelium. American Journal Of Physiology 1994, 266: c198-c205. PMID: 8304416, DOI: 10.1152/ajpcell.1994.266.1.c198.Peer-Reviewed Original ResearchConceptsCotransporter activityCiliary epitheliumATPase inhibitionPotassium channel blockerNonpigmented ciliary epitheliumChannel blockersOuabain treatmentStimulatory effectPotassium effluxExtracellular concentrationCellular sodiumPotassium channelsCellular potassiumOuabain-induced activationIntracellular potassiumPotassium influxEpitheliumCell linesCotransporter stimulationCotransporterInhibitionPotassium efflux rateEfflux rateATPase activityUptake component