2017
Novel therapeutics for Stargardt disease
Lu LJ, Liu J, Adelman RA. Novel therapeutics for Stargardt disease. Graefe's Archive For Clinical And Experimental Ophthalmology 2017, 255: 1057-1062. PMID: 28285324, DOI: 10.1007/s00417-017-3619-8.Peer-Reviewed Original ResearchConceptsStargardt diseaseVision lossABCA4 geneStem cell transplantationSevere vision lossPromising treatment candidateNovel therapeutic strategiesRetinal pigment epitheliumStem cell therapyVisual acuityStandard treatmentMacular degenerationTreatment candidatesHESC-RPE cellsStargardt patientsTherapeutic strategiesPharmacological agentsPigment epitheliumMacular dystrophyNovel therapeuticsPatientsDiseaseVisual cyclePrevalent formSecond decade
2012
Focused ultrasound facilitated thermo-chemotherapy for targeted retinoblastoma treatment: A modeling study
Wang S, Mahesh SP, Liu J, Geist C, Zderic V. Focused ultrasound facilitated thermo-chemotherapy for targeted retinoblastoma treatment: A modeling study. Experimental Eye Research 2012, 100: 17-25. PMID: 22564972, DOI: 10.1016/j.exer.2012.04.009.Peer-Reviewed Original ResearchConceptsFocused ultrasoundType of treatmentVision preservationRetinoblastoma treatmentIntraocular tumorsTreatment paradigmRabbit eyesTumor areaEarly detectionTumorsVivo studiesRetinoblastomaHyperthermic temperature rangeCommon typeTreatmentDrug deliveryFUS parametersUltrasoundEye structuresHyperthermiaViable optionThermo-chemotherapyDeliveryTherapy