2009
p53 responsive elements in human retrotransposons
Harris CR, DeWan A, Zupnick A, Normart R, Gabriel A, Prives C, Levine AJ, Hoh J. p53 responsive elements in human retrotransposons. Oncogene 2009, 28: 3857-3865. PMID: 19718052, PMCID: PMC3193277, DOI: 10.1038/onc.2009.246.Peer-Reviewed Original ResearchConceptsP53-responsive elementResponsive elementHuman genomeL1 promoterL1 elementsP53 DNA binding sitesRepetitive DNA elementsDNA binding sitesL1 mRNAP53 proteinCytosine methylationNuclear element-1DNA elementsGenomic stabilityHuman retrotransposonsP53-dependent processesGenomic changesGenomic protectionGenomeElement 1L1 mRNA expressionProteinBinding sitesPromoterL1 protein
2001
Two Approaches for Consolidating Results from Genome Scans of Complex Traits: Selection Methods and Scan Statistics
Gordon D, Hoh J, Finch S, Levenstien M, Edington J, EdingtonLi W, Majewski J, Ott J. Two Approaches for Consolidating Results from Genome Scans of Complex Traits: Selection Methods and Scan Statistics. Genetic Epidemiology 2001, 21: s396-s402. PMID: 11793706, DOI: 10.1002/gepi.2001.21.s1.s396.Peer-Reviewed Original ResearchConceptsAffected sib-pair testsFraction of markersLevel of significanceScan statisticTwo-point lodSusceptibility genesSib-pair testSingle-locus statisticsEmpirical p-valuesSimulated null dataSib pairsGenome scanMarker lociTDT testLinkage analysisComplex traitsGenotype dataSignificance levelGenesEmpirical significance levelsP-valueChromosomeReplicated 5Analysis of simulated dataReplication