1999
Motion Opponency in Visual Cortex
Heeger D, Boynton G, Demb J, Seidemann E, Newsome W. Motion Opponency in Visual Cortex. Journal Of Neuroscience 1999, 19: 7162-7174. PMID: 10436069, PMCID: PMC6782843, DOI: 10.1523/jneurosci.19-16-07162.1999.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDiscrimination, PsychologicalFemaleHumansMacaca mulattaMagnetic Resonance ImagingMaleMotion PerceptionNeuronsSpecies SpecificityVisual CortexConceptsFunctional magnetic resonance imagingVisual motion perceptionMotion opponencyMotion perceptionVisual cortexSecondary visual cortical areasHuman MT complexHuman visual cortexDirection-selective signalsVisual cortical areasSensitive brain areasPrimary visual cortexMacaque monkey brainMagnetic resonance imagingPopulations of neuronsMultiunit electrophysiological recordingsBrain activityPerceptual studiesNeuronal correlatesFMRI measurementsArea MTCortical areasBrain areasMonkey brainResonance imagingNormal planum temporale asymmetry in dyslexics with a magnocellular pathway deficit
Best M, Demb J. Normal planum temporale asymmetry in dyslexics with a magnocellular pathway deficit. Neuroreport 1999, 10: 607-612. PMID: 10208598, DOI: 10.1097/00001756-199902250-00030.Peer-Reviewed Original ResearchMeSH KeywordsAdultAuditory PathwaysDyslexiaFemaleHumansMagnetic Resonance ImagingMaleReference ValuesTemporal LobeVisual PathwaysConceptsPlanum temporalePT asymmetryPlanum temporale asymmetrySagittal magnetic resonance imagesMagnocellular visual pathwayMagnocellular deficitVisual pathwayAbnormal symmetryDifferent subtypesPathway deficitsMagnetic resonance imagesSubject groupsMagnocellular pathway deficitDyslexic subjectsResonance imagesDeficitsSubjectsHemispheric symmetryGroupAbnormalitiesSubtypesNeuronal basis of contrast discrimination
Boynton G, Demb J, Glover G, Heeger D. Neuronal basis of contrast discrimination. Vision Research 1999, 39: 257-269. PMID: 10326134, DOI: 10.1016/s0042-6989(98)00113-8.Peer-Reviewed Original ResearchMeSH KeywordsContrast SensitivityHumansMagnetic Resonance ImagingPhotic StimulationPsychophysicsVisual CortexConceptsVisual cortical areasAverage neuronal activityFunctional magnetic resonance imagingFMRI responsesNeuronal activityCortical areasEarly visual cortical areasMagnetic resonance imagingVisual areas V1Contrast increment thresholdsIncrement thresholdsEarly visual cortexNeuronal responsesBrain areasVisual cortexResonance imagingArea V1Neuronal basisPooled activityStimulus intervalStimulus contrastBaseline contrastNeuronal signalsBrain activityHuman brain activity
1998
Functional Magnetic Resonance Imaging of Early Visual Pathways in Dyslexia
Demb J, Boynton G, Heeger D. Functional Magnetic Resonance Imaging of Early Visual Pathways in Dyslexia. Journal Of Neuroscience 1998, 18: 6939-6951. PMID: 9712663, PMCID: PMC6792964, DOI: 10.1523/jneurosci.18-17-06939.1998.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain MappingDyslexiaFemaleHumansMagnetic Resonance ImagingMalePhotic StimulationPsychophysicsReadingVisual PathwaysConceptsFunctional magnetic resonance imagingMagnetic resonance imagingBrain activityResonance imagingM pathwayReduced brain activityPrimary visual cortexMotion-sensitive areasSpeed discriminationPerceptual thresholdHigher V1Pathway abnormalitiesVisual motion perceptionEarly visual pathwayGroups of dyslexicsVisual cortexVisual pathwayLower perceptual thresholdsExtrastriate areasArea MTMagnocellular pathwayStimulus speedPathway inputEarly visual systemNormal readers
1997
Brain activity in visual cortex predicts individual differences in reading performance
Demb J, Boynton G, Heeger D. Brain activity in visual cortex predicts individual differences in reading performance. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 13363-13366. PMID: 9371851, PMCID: PMC24314, DOI: 10.1073/pnas.94.24.13363.Peer-Reviewed Original ResearchConceptsBrain activityIndividual differencesSpecific visual pathwaysM pathwayCortical visual areasPrimary visual cortexFunctional magnetic resonance imagingMagnetic resonance imagingPathway abnormalitiesVisual cortexVisual pathwayResonance imagingVisual areasMagnocellular pathwayReading abilityPathway inputSignificant correlationReduced activityDyslexicsDyslexiaPathwayStrong relationshipActivityAbnormalitiesCortex
1995
Functional MRI measurement of language Lateralization in Wada-tested patients
Desmond J, Sum J, Wagner A, Demb J, Shear P, Glover G, Gabrieli J, Morrell M. Functional MRI measurement of language Lateralization in Wada-tested patients. Brain 1995, 118: 1411-1419. PMID: 8595473, DOI: 10.1093/brain/118.6.1411.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmobarbitalDominance, CerebralEpilepsy, Temporal LobeFemaleFunctional LateralityHumansLanguageMagnetic Resonance ImagingMaleMiddle AgedPreoperative CareConceptsLanguage lateralizationFunctional MRIPerceptual judgmentsHuman cognitive processesInferior frontal gyrusBrodmann area 45Functional MRI measurementsHemispheric language dominanceCognitive processesSemantic relativeFrontal gyrusLanguage dominanceFMRI scansArea 45LateralizationTemporal lobe epilepsyJudgmentsOrbital cortexPre-surgical evaluationLobe epilepsyNon-invasive measureTest assessmentSignificant clinical potentialPatientsGyrusSemantic encoding and retrieval in the left inferior prefrontal cortex: a functional MRI study of task difficulty and process specificity
Demb J, Desmond J, Wagner A, Vaidya C, Glover G, Gabrieli J. Semantic encoding and retrieval in the left inferior prefrontal cortex: a functional MRI study of task difficulty and process specificity. Journal Of Neuroscience 1995, 15: 5870-5878. PMID: 7666172, PMCID: PMC6577672, DOI: 10.1523/jneurosci.15-09-05870.1995.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBrain MappingFemaleHumansLanguageMagnetic Resonance ImagingMaleMemoryPrefrontal CortexReaction TimeConceptsLeft inferior prefrontal cortexFunctional magnetic resonance imagingInferior prefrontal cortexSemantic encodingRepetition primingTask difficultyPrefrontal cortexPrefrontal cortical functionFunctional MRI studyIntentional recollectionLIPC activationNonsemantic encodingSemantic processingExecutive systemTime wordsSame wordsNeural activityRelative difficultyEncodingWordsCortical functionProcess specificitySemantic informationLine retrievalPriming