2013
Adaptation to Background Light Enables Contrast Coding at Rod Bipolar Cell Synapses
Ke JB, Wang YV, Borghuis BG, Cembrowski MS, Riecke H, Kath WL, Demb JB, Singer JH. Adaptation to Background Light Enables Contrast Coding at Rod Bipolar Cell Synapses. Neuron 2013, 81: 388-401. PMID: 24373883, PMCID: PMC4267681, DOI: 10.1016/j.neuron.2013.10.054.Peer-Reviewed Original ResearchMeSH Keywords2-Amino-5-phosphonovalerateAdaptation, OcularAnimalsBiophysicsComputer SimulationExcitatory Amino Acid AntagonistsGlucosamine 6-Phosphate N-AcetyltransferaseGreen Fluorescent ProteinsIn Vitro TechniquesLightMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicModels, NeurologicalPatch-Clamp TechniquesQuinoxalinesRetinal Bipolar CellsRetinal Rod Photoreceptor CellsSynapsesVisual Pathways
2008
Distinct expressions of contrast gain control in parallel synaptic pathways converging on a retinal ganglion cell
Beaudoin DL, Manookin MB, Demb JB. Distinct expressions of contrast gain control in parallel synaptic pathways converging on a retinal ganglion cell. The Journal Of Physiology 2008, 586: 5487-5502. PMID: 18832424, PMCID: PMC2655385, DOI: 10.1113/jphysiol.2008.156224.Peer-Reviewed Original ResearchConceptsCone bipolar cellsOFF ganglion cellsRod bipolar cellsGanglion cellsRetinal ganglion cellsBipolar cellsInhibitory inputsExcitatory inputsSynaptic pathwaysContrast gain controlOFF cone bipolar cellsIonotropic glutamate receptor antagonistsY-type ganglion cellsRod bipolar pathwayAII amacrine cellsGlutamate receptor antagonistsGanglion cell firingWhole-cell recordingsLoose-patch recordingsAmacrine cellsReceptor antagonistRetinal pathwaysAII cellsSynaptic mechanismsSynaptic currents