2017
Identification of Intrinsic Axon Growth Modulators for Intact CNS Neurons after Injury
Fink KL, López-Giráldez F, Kim IJ, Strittmatter SM, Cafferty WB. Identification of Intrinsic Axon Growth Modulators for Intact CNS Neurons after Injury. Cell Reports 2017, 18: 2687-2701. PMID: 28297672, PMCID: PMC5389739, DOI: 10.1016/j.celrep.2017.02.058.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCentral nervous systemFunctional recoveryIntact neuronsAdult mammalian central nervous systemPartial spinal cord injuryInjury-induced sproutingUnilateral brainstem lesionsGreater functional recoverySpontaneous functional recoveryCorticospinal motor neuronsCorticospinal tract axonsMammalian central nervous systemWild-type miceNew synapse formationGrowth modulatorsAdjacent injuryBrainstem lesionsCord injuryFunctional deficitsIntact circuitryCNS neuronsMotor neuronsCircuit plasticityNervous system
2010
Laminar Restriction of Retinal Ganglion Cell Dendrites and Axons: Subtype-Specific Developmental Patterns Revealed with Transgenic Markers
Kim IJ, Zhang Y, Meister M, Sanes JR. Laminar Restriction of Retinal Ganglion Cell Dendrites and Axons: Subtype-Specific Developmental Patterns Revealed with Transgenic Markers. Journal Of Neuroscience 2010, 30: 1452-1462. PMID: 20107072, PMCID: PMC2822471, DOI: 10.1523/jneurosci.4779-09.2010.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsEarly postnatal stagesRGC subsetsSuperior colliculusSubset of RGCsRetinal ganglion cell dendritesPostnatal stagesGanglion cell dendritesInner plexiform layerLateral geniculate nucleusDevelopment of RGCsSpecific sublaminaeDistinct functional signaturesSubpial zoneGanglion cellsPlexiform layerCell dendritesAxonal projectionsDendritic arborsGeniculate nucleusSubtype-specific featuresAxonal arborsRetinorecipient layersMouse transgenic linesDiffuse pattern