R-Spondin 1 Suppresses Inflammatory Cytokine Production in Human Cortical Astrocytes
Logan R, Bhatta S, Sutova H, Hafler B, Miller S. R-Spondin 1 Suppresses Inflammatory Cytokine Production in Human Cortical Astrocytes. Neuroglia 2024, 5: 445-451. DOI: 10.3390/neuroglia5040028.Peer-Reviewed Original ResearchCentral nervous systemCytokine releaseSignaling pathwayCentral nervous system inflammationR-spondinStem cell-derived astrocytesInfluence central nervous systemHuman induced pluripotent stem cell-derived astrocytesCytokine array kitSuppression of inflammatory cytokinesModulate cytokine releaseWnt signalingInfluence inflammatory responsesModulate immune responsesInflammatory cytokine productionCytokine-cytokine receptor interactionInflammatory cytokine releaseContext of inflammationLGR6 receptorsPathway enrichment analysisCXCL12 levelsHuman cortical astrocytesIL-23TNF signaling pathwayIFN-g