2022
Microbiome and immune-mediated dry eye: a review
Watane A, Raolji S, Cavuoto K, Galor A. Microbiome and immune-mediated dry eye: a review. BMJ Open Ophthalmology 2022, 7: e000956. PMID: 36161855, PMCID: PMC9214397, DOI: 10.1136/bmjophth-2021-000956.Peer-Reviewed Original ResearchConceptsOcular surface microbiomeDry eyeAutoimmune diseasesFecal microbial transplantGut microbiome changesCertain autoimmune diseasesLymphocyte responsesMicrobial transplantTherapeutic strategiesImmune systemMicrobiome changesGut microbiomeDiseaseKey articlesEyesLess informationMicrobiome variesMicrobiome manipulationMicrobiomeSurface microbiomeReviewTransplantIndividualsSeverityDemographics
2020
Gut microbial dysbiosis in individuals with Sjögren’s syndrome
Mendez R, Watane A, Farhangi M, Cavuoto KM, Leith T, Budree S, Galor A, Banerjee S. Gut microbial dysbiosis in individuals with Sjögren’s syndrome. Microbial Cell Factories 2020, 19: 90. PMID: 32293464, PMCID: PMC7158097, DOI: 10.1186/s12934-020-01348-7.Peer-Reviewed Original ResearchConceptsHealthy controlsDE symptomsFull criteriaGut microbiomeGut microbial dysbiosisDepletion of FirmicutesExpansion of ProteobacteriaDry eyeSjögren's syndromeMicrobial dysbiosisMicrobiome alterationsDE measuresConclusionsIn conclusionMicrobial compositionEye measuresSyndromeSymptomsSjögrenDifferential clusteringAssociationSignsIndividualsPrinciple co-ordinate analysisPhylum levelMicrobiome