Robert Schonberger, MD, MHCDS
Research & Publications
Biography
News
Research Summary
Dr. Schonberger has a research interest in developing new anesthesia healthcare delivery models that aim to improve care coordination on the day of surgery with the aim to facilitate longitudinal cardiovascular risk-factor recognition and treatment in patients presenting for anesthesia.
He is also involved in several projects associated with perioperative care of the cardiothoracic surgery patient including the development of novel extracorporeal oxygenation techniques as well as other interventions to improve the safety and outcomes associated with surgeries involving patients with cardiac disease.
Extensive Research Description
Anesthetic Induction Dose Adjustment Among Elderly Surgical Patients
Integrating perioperative care into the treatment of hypertension.
Perioperative beta-blockade.
Novel therapies to reduce and treat gaseous microemboli.
Pharmacology and physiology of extra corporeal support.
Coauthors
Research Interests
Anesthesiology; Extracorporeal Circulation; Cardiac Surgical Procedures; Hypertension; Outcome and Process Assessment, Health Care; Geriatric Assessment
Public Health Interests
Cardiovascular Diseases; Epidemiology Methods; Health Care Management
Selected Publications
- Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational AnalysisMathis M, Janda A, Kheterpal S, Schonberger R, Pagani F, Engoren M, Mentz G, Shook D, Muehlschlegel J, Cassidy R, Clark D, Colquhoun D, Freundlich R, Jewell E. Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis. Anesthesiology 2023, 139: 122-141. PMID: 37094103, PMCID: PMC10524016, DOI: 10.1097/aln.0000000000004593.
- Association of Adherence to Individual Components of STS Cardiac Surgery Antibiotic Guidelines and Post-operative InfectionsBardia A, Michel G, Farela A, Fisher C, Mori M, Huttler J, Lang A, Geirsson A, Schonberger R. Association of Adherence to Individual Components of STS Cardiac Surgery Antibiotic Guidelines and Post-operative Infections. Journal Of Thoracic And Cardiovascular Surgery 2023 PMID: 37075942, DOI: 10.1016/j.jtcvs.2023.03.031.
- Geospatial analysis of patients’ social determinants of health for health systems science and disparity researchPearson J, Jacobson C, Ugochukwu N, Asare E, Kan K, Pace N, Han J, Wan N, Schonberger R, Andreae M. Geospatial analysis of patients’ social determinants of health for health systems science and disparity research. International Anesthesiology Clinics 2022, 61: 49-62. PMID: 36480649, PMCID: PMC10107426, DOI: 10.1097/aia.0000000000000389.
- Efficacy and Safety of Sugammadex to Shorten Time-to-Extubation Following Cardiac Surgery: A Single-Center Randomized Placebo-Controlled TrialBardia A, Treggiari M, Dai F, Johnson C, Singh M, Kunze K, Tickoo M, Tantawy H, Giersson A, Darr U, Schonberger R. Efficacy and Safety of Sugammadex to Shorten Time-to-Extubation Following Cardiac Surgery: A Single-Center Randomized Placebo-Controlled Trial. Critical Care Explorations 2022, 4: e0821. PMID: 36601562, PMCID: PMC9788969, DOI: 10.1097/cce.0000000000000821.
- Oxygen administration during surgery and postoperative organ injury: observational cohort studyMcIlroy D, Shotwell M, Lopez M, Vaughn M, Olsen J, Hennessy C, Wanderer J, Semler M, Rice T, Kheterpal S, Billings F, Group M, Cuff G, Freundlich R, Kurz A, Naik B, Mathis M, Schonberger R. Oxygen administration during surgery and postoperative organ injury: observational cohort study. The BMJ 2022, 379: e070941. PMID: 36450405, PMCID: PMC9710248, DOI: 10.1136/bmj-2022-070941.
- Association between choice of reversal agent for neuromuscular block and postoperative pulmonary complications in patients at increased risk undergoing non-emergency surgery: STIL-STRONGER, a multicentre matched cohort studyColquhoun D, Vaughn M, Bash L, Janda A, Shah N, Ghaferi A, Sjoding M, Mentz G, Kheterpal S, Committee M, Craft R, Domino K, Freundlich R, Mathis M, McCormick P, Naik B, Ruiz J, Schonberger R, Schroeder R, Stewart A, Taicher B, Tingle S, Togioka B, Urman R, Vachhani S. Association between choice of reversal agent for neuromuscular block and postoperative pulmonary complications in patients at increased risk undergoing non-emergency surgery: STIL-STRONGER, a multicentre matched cohort study. British Journal Of Anaesthesia 2022, 130: e148-e159. PMID: 35691703, PMCID: PMC9875908, DOI: 10.1016/j.bja.2022.04.023.
- Chasing Ghosts: Unexplained Artifactual Echogenicity on the Aortic Valve Leading to Unwarranted SurgeryBlitz D, Mahmood F, Tickoo M, Schonberger R, Bardia A. Chasing Ghosts: Unexplained Artifactual Echogenicity on the Aortic Valve Leading to Unwarranted Surgery. Case 2019, 3: 107-109. PMID: 31286089, PMCID: PMC6588731, DOI: 10.1016/j.case.2019.01.002.
- Preoperative chlorhexidine mouthwash to reduce pneumonia after cardiac surgery: A systematic review and meta-analysisBardia A, Blitz D, Dai F, Hersey D, Jinadasa S, Tickoo M, Schonberger RB. Preoperative chlorhexidine mouthwash to reduce pneumonia after cardiac surgery: A systematic review and meta-analysis. Journal Of Thoracic And Cardiovascular Surgery 2019, 158: 1094-1100. PMID: 30826096, DOI: 10.1016/j.jtcvs.2019.01.014.
- Succinylcholine Use and Dantrolene Availability for Malignant Hyperthermia Treatment: Database Analyses and Systematic Review.Larach MG, Klumpner TT, Brandom BW, Vaughn MT, Belani KG, Herlich A, Kim TW, Limoncelli J, Riazi S, Sivak EL, Capacchione J, Mashman D, Kheterpal S, Kooij F, Wilczak J, Soto R, Berris J, Price Z, Lins S, Coles P, Harris JM, Cummings KC, Berman MF, Nanamori M, Adelman BT, Wedeven C, LaGorio J, McCormick PJ, Tom S, Aziz MF, Coffman T, Ellis TA, Molina S, Peterson W, Mackey SC, van Klei WA, Ginde AA, Biggs DA, Neuman MD, Craft RM, Pace NL, Paganelli WC, Durieux ME, Nair BJ, Wanderer JP, Miller SA, Helsten DL, Turnbull ZA, Schonberger RB. Succinylcholine Use and Dantrolene Availability for Malignant Hyperthermia Treatment: Database Analyses and Systematic Review. Anesthesiology 2019, 130: 41-54. PMID: 30550426, DOI: 10.1097/ALN.0000000000002490.
- Elevated preoperative blood pressures in adult surgical patients are highly predictive of elevated home blood pressuresSchonberger RB, Nwozuzu A, Zafar J, Chen E, Kigwana S, Monteiro MM, Charchaflieh J, Sophanphattana S, Dai F, Burg MM. Elevated preoperative blood pressures in adult surgical patients are highly predictive of elevated home blood pressures. International Journal Of Cardiology Cardiovascular Risk And Prevention 2018, 12: 303-310. PMID: 29486981, PMCID: PMC5938112, DOI: 10.1016/j.jash.2018.01.012.
- Quantification of Postmembrane Gaseous Microembolization During Venoarterial Extracorporeal Membrane OxygenationJiao Y, Gipson KE, Bonde P, Mangi A, Hagberg R, Rosinski DJ, Gross JB, Schonberger RB. Quantification of Postmembrane Gaseous Microembolization During Venoarterial Extracorporeal Membrane Oxygenation. ASAIO Journal 2018, 64: 31-37. PMID: 28557862, DOI: 10.1097/mat.0000000000000598.
- Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) in Adult Patients – Many Questions, Few Answers, and Hard ChoicesBardia A, Schonberger RB. Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) in Adult Patients – Many Questions, Few Answers, and Hard Choices. Journal Of Cardiothoracic And Vascular Anesthesia 2017, 32: 1183-1184. PMID: 29276089, DOI: 10.1053/j.jvca.2017.10.037.
- The effect of race on postsurgical ambulatory medical follow-up among United States VeteransSchonberger RB, Dai F, Brandt C, Burg MM. The effect of race on postsurgical ambulatory medical follow-up among United States Veterans. Journal Of Clinical Anesthesia 2017, 40: 55-61. PMID: 28625448, PMCID: PMC5490668, DOI: 10.1016/j.jclinane.2016.11.002.
- A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General AnesthesiaChen EY, Sukumar N, Dai F, Akhtar S, Schonberger RB. A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia. Journal Of Cardiothoracic And Vascular Anesthesia 2017, 32: 666-671. PMID: 29277298, PMCID: PMC5766429, DOI: 10.1053/j.jvca.2017.07.009.
- Orthogonal Views of Coronary Vessels: A Method for Imaging the Delivery of Blood Cardioplegia Using Transesophageal Echocardiography.Maracaja Neto LF, Modak R, Schonberger RB. Orthogonal Views of Coronary Vessels: A Method for Imaging the Delivery of Blood Cardioplegia Using Transesophageal Echocardiography. Anesthesia And Analgesia 2017, 124: 1087-1090. PMID: 28099289, DOI: 10.1213/ANE.0000000000001872.
- Medically Complex PatientsSchonberger RB, Rosenbaum SH. Medically Complex Patients. Anesthesiology Clinics 2016, 34: xv-xvi. PMID: 27816137, DOI: 10.1016/j.anclin.2016.09.001.
- Medically Complex PatientsSchonberger R, Rosenbaum S. Medically Complex Patients. Anesthesiology Clinics 2016, 34: i. DOI: 10.1016/s1932-2275(16)30086-6.
- A Retrospective Observational Study of Anesthetic Induction Dosing Practices in Female Elderly Surgical Patients: Are We Overdosing Older Patients?Akhtar S, Heng J, Dai F, Schonberger RB, Burg MM. A Retrospective Observational Study of Anesthetic Induction Dosing Practices in Female Elderly Surgical Patients: Are We Overdosing Older Patients? Drugs & Aging 2016, 33: 737-746. PMID: 27581549, DOI: 10.1007/s40266-016-0394-x.
- Is There Evidence for Systematic Upcoding of ASA Physical Status Coincident With Payer Incentives? A Regression Discontinuity Analysis of the National Anesthesia Clinical Outcomes RegistrySchonberger R, Dutton R, Dai F. Is There Evidence for Systematic Upcoding of ASA Physical Status Coincident With Payer Incentives? A Regression Discontinuity Analysis of the National Anesthesia Clinical Outcomes Registry. Survey Of Anesthesiology 2016, 60: 155-156. DOI: 10.1097/01.sa.0000484822.65304.b3.
- Mobile Extracorporeal Membrane Oxygenation Teams: The North American Versus the European ExperienceNwozuzu A, Fontes ML, Schonberger RB. Mobile Extracorporeal Membrane Oxygenation Teams: The North American Versus the European Experience. Journal Of Cardiothoracic And Vascular Anesthesia 2016, 30: 1441-1448. PMID: 27686513, PMCID: PMC5130610, DOI: 10.1053/j.jvca.2016.06.005.
- Does intravenous induction dosing among patients undergoing gastrointestinal surgical procedures follow current recommendations: a study of contemporary practiceAkhtar S, Liu J, Heng J, Dai F, Schonberger RB, Burg MM. Does intravenous induction dosing among patients undergoing gastrointestinal surgical procedures follow current recommendations: a study of contemporary practice. Journal Of Clinical Anesthesia 2016, 33: 208-215. PMID: 27555166, DOI: 10.1016/j.jclinane.2016.02.001.
- Rebranding the Perioperative Surgical Home: Lessons From the Duke ExperienceSchonberger RB. Rebranding the Perioperative Surgical Home: Lessons From the Duke Experience. Journal Of Cardiothoracic And Vascular Anesthesia 2016, 30: 1064-1066. PMID: 27313120, DOI: 10.1053/j.jvca.2016.03.143.
- The Surgical Care Improvement Project Antibiotic GuidelinesSchonberger R, Barash P, Lagasse R. The Surgical Care Improvement Project Antibiotic Guidelines. Survey Of Anesthesiology 2016, 60: 27. DOI: 10.1097/01.sa.0000475676.92928.a5.
- Is There Evidence for Systematic Upcoding of ASA Physical Status Coincident with Payer Incentives? A Regression Discontinuity Analysis of the National Anesthesia Clinical Outcomes RegistrySchonberger RB, Dutton RP, Dai F. Is There Evidence for Systematic Upcoding of ASA Physical Status Coincident with Payer Incentives? A Regression Discontinuity Analysis of the National Anesthesia Clinical Outcomes Registry. Anesthesia & Analgesia 2016, 122: 243-250. PMID: 26360960, PMCID: PMC4684754, DOI: 10.1213/ane.0000000000000917.
- Ambulatory Medical Follow-Up in the Year After Surgery and Subsequent Survival in a National Cohort of Veterans Health Administration Surgical PatientsSchonberger RB, Dai F, Brandt C, Burg MM. Ambulatory Medical Follow-Up in the Year After Surgery and Subsequent Survival in a National Cohort of Veterans Health Administration Surgical Patients. Journal Of Cardiothoracic And Vascular Anesthesia 2015, 30: 671-679. PMID: 27021176, PMCID: PMC5499041, DOI: 10.1053/j.jvca.2015.12.019.
- The Importance of Cost as an Outcome in Anesthesiology ResearchSchonberger RB. The Importance of Cost as an Outcome in Anesthesiology Research. Journal Of Cardiothoracic And Vascular Anesthesia 2015, 30: 10-11. PMID: 26711445, DOI: 10.1053/j.jvca.2015.10.016.
- Balancing Model Performance and Simplicity to Predict Postoperative Primary Care Blood Pressure ElevationSchonberger RB, Dai F, Brandt CA, Burg MM. Balancing Model Performance and Simplicity to Predict Postoperative Primary Care Blood Pressure Elevation. Anesthesia & Analgesia 2015, 121: 632-641. PMID: 26214552, PMCID: PMC4545382, DOI: 10.1213/ane.0000000000000860.
- The Surgical Care Improvement Project Antibiotic GuidelinesSchonberger RB, Barash PG, Lagasse RS. The Surgical Care Improvement Project Antibiotic Guidelines. Anesthesia & Analgesia 2015, 121: 397-403. PMID: 26197373, PMCID: PMC4510848, DOI: 10.1213/ane.0000000000000735.
- S3. The Outlook of Physician Histories: J. Marion Sims and “The Discovery of Anesthesia”Rosenbloom J, Schonberger R. S3. The Outlook of Physician Histories: J. Marion Sims and “The Discovery of Anesthesia”. Journal Of Anesthesia History 2015, 1: 86-87. PMID: 26930083, DOI: 10.1016/j.janh.2015.07.005.
- The outlook of physician histories: J. Marion Sims and ‘The Discovery of Anaesthesia’Rosenbloom JM, Schonberger RB. The outlook of physician histories: J. Marion Sims and ‘The Discovery of Anaesthesia’. Medical Humanities 2015, 41: 102. PMID: 26048369, DOI: 10.1136/medhum-2015-010680.
- Toward an Understanding of the Equality of Pain: Crawford Long and the Development of Anesthesia in Antebellum GeorgiaRosenbloom JM, Schonberger RB. Toward an Understanding of the Equality of Pain: Crawford Long and the Development of Anesthesia in Antebellum Georgia. Journal Of Anesthesia History 2014, 1: 14-17. PMID: 25748368, DOI: 10.1016/j.janh.2014.11.003.
- Preoperative Depression Symptom Severity and Its Impact on Adherence to Preoperative Beta-Blocker TherapySchonberger RB, Feinleib J, Holt N, Dai F, Brandt C, Burg MM. Preoperative Depression Symptom Severity and Its Impact on Adherence to Preoperative Beta-Blocker Therapy. Journal Of Cardiothoracic And Vascular Anesthesia 2014, 28: 1467-1473. PMID: 25263776, PMCID: PMC4258545, DOI: 10.1053/j.jvca.2014.05.006.
- Random Errors and Misclassification BiasSchonberger RB. Random Errors and Misclassification Bias. Anesthesia & Analgesia 2014, 119: 497-498. PMID: 25046792, PMCID: PMC4107355, DOI: 10.1213/ane.0000000000000251.
- Ideal Blood Pressure Management and our SpecialtySchonberger RB. Ideal Blood Pressure Management and our Specialty. Journal Of Neurosurgical Anesthesiology 2014, 26: 270-271. PMID: 24905036, PMCID: PMC4101913, DOI: 10.1097/ana.0000000000000012.
- Handheld Doppler to Improve Pulse Checks during Resuscitation of Putative Pulseless Electrical Activity ArrestSchonberger RB, Lampert RJ, Mandel EI, Feinleib J, Gong Z, Honiden S. Handheld Doppler to Improve Pulse Checks during Resuscitation of Putative Pulseless Electrical Activity Arrest. Anesthesiology 2014, 120: 1042-1045. PMID: 24335750, PMCID: PMC3975650, DOI: 10.1097/aln.0000000000000106.
- Variation in Surgical Quality Measure Adherence within Hospital Referral Regions: Do Publicly Reported Surgical Quality Measures Distinguish among Hospitals That Patients Are Likely to Compare?Safavi KC, Dai F, Gilbertsen TA, Schonberger RB. Variation in Surgical Quality Measure Adherence within Hospital Referral Regions: Do Publicly Reported Surgical Quality Measures Distinguish among Hospitals That Patients Are Likely to Compare? Health Services Research 2014, 49: 1108-1120. PMID: 24611578, PMCID: PMC4111773, DOI: 10.1111/1475-6773.12164.
- Elimination of Gaseous Microemboli From Cardiopulmonary Bypass Using Hypobaric OxygenationGipson KE, Rosinski DJ, Schonberger RB, Kubera C, Mathew ES, Nichols F, Dyckman W, Courtin F, Sherburne B, Bordey AF, Gross JB. Elimination of Gaseous Microemboli From Cardiopulmonary Bypass Using Hypobaric Oxygenation. The Annals Of Thoracic Surgery 2013, 97: 879-886. PMID: 24206970, PMCID: PMC4294693, DOI: 10.1016/j.athoracsur.2013.08.074.
- New Utility for an Old ToolOdonkor CA, Schonberger RB, Dai F, Shelley KH, Silverman DG, Barash PG. New Utility for an Old Tool. American Journal Of Physical Medicine & Rehabilitation 2013, 92: 849-863. PMID: 24051992, PMCID: PMC3850792, DOI: 10.1097/phm.0b013e3182a51ac5.
- The Problem of Controlling for Imperfectly Measured Confounders on Dissimilar Populations: A Database Simulation StudySchonberger RB, Gilbertsen T, Dai F. The Problem of Controlling for Imperfectly Measured Confounders on Dissimilar Populations: A Database Simulation Study. Journal Of Cardiothoracic And Vascular Anesthesia 2013, 28: 247-254. PMID: 23962461, PMCID: PMC3926910, DOI: 10.1053/j.jvca.2013.03.014.
- They Did What … ?Schonberger RB, Barash PG. They Did What … ? Anesthesia & Analgesia 2013, 117: 3-5. PMID: 23788736, PMCID: PMC3696483, DOI: 10.1213/ane.0b013e318259ef55.
- Atenolol is Associated With Lower Day-of-Surgery Heart Rate Compared to Long- and Short-Acting MetoprololSchonberger RB, Brandt C, Feinleib J, Dai F, Burg MM. Atenolol is Associated With Lower Day-of-Surgery Heart Rate Compared to Long- and Short-Acting Metoprolol. Journal Of Cardiothoracic And Vascular Anesthesia 2012, 27: 298-304. PMID: 22889605, PMCID: PMC3557658, DOI: 10.1053/j.jvca.2012.06.021.
- Etymologia: prion.Schonberger LB, Schonberger RB. Etymologia: prion. Emerging Infectious Diseases 2012, 18: 1030-1031. PMID: 22607731, PMCID: PMC3358176, DOI: 10.3201/eid1806.120271.
- Impact Versus Impact FactorSchonberger RB, Barash PG. Impact Versus Impact Factor. Anesthesia & Analgesia 2012, 115: 1286-1287. PMID: 22584555, PMCID: PMC3482412, DOI: 10.1213/ane.0b013e318259ef6b.
- Beta-Blocker Withdrawal Among Patients Presenting for Surgery from HomeSchonberger RB, Lukens CL, Turkoglu OD, Feinleib JL, Haspel KL, Burg MM. Beta-Blocker Withdrawal Among Patients Presenting for Surgery from Home. Journal Of Cardiothoracic And Vascular Anesthesia 2012, 26: 1029-1033. PMID: 22418043, PMCID: PMC3419315, DOI: 10.1053/j.jvca.2012.01.024.
- The Relationship Between Preoperative and Primary Care Blood Pressure Among Veterans Presenting from Home for SurgerySchonberger RB, Burg MM, Holt N, Lukens CL, Dai F, Brandt C. The Relationship Between Preoperative and Primary Care Blood Pressure Among Veterans Presenting from Home for Surgery. Anesthesia & Analgesia 2011, 114: 205-214. PMID: 22075017, PMCID: PMC3282161, DOI: 10.1213/ane.0b013e318239c4c1.
- Brain DeathSchonberger RB, Rosenbaum SH. Brain Death. In: Norman GAV, ed. Clinical Ethics in Anesthesiology: A Case-Based Textbook. Cambridge: Cambridge University Press; 2011:108-13.
- Ethical ConsiderationsSchonberger RB, Rosenbaum SH. Ethical Considerations. In: Ruskin KJ, Rosenbaum SH, eds. Anesthesia Emergencies. Oxford: Oxford University Press; 2011:77-84.
- Brain deathSchonberger R, Rosenbaum S. Brain death. 2010, 108-113. DOI: 10.1017/cbo9780511841361.021.
- Ethical ConsiderationsSchonberger R, Rosenbaum S. Ethical Considerations. 2010, 76-83. DOI: 10.1093/med/9780195396713.003.0004.
- The Anesthesia Patient with Acute Coronary SyndromeSchonberger RB, Haddadin AS. The Anesthesia Patient with Acute Coronary Syndrome. Anesthesiology Clinics 2010, 28: 55-66. PMID: 20400040, DOI: 10.1016/j.anclin.2010.01.001.
- Not Much Novel Under the SunSchonberger RB, Rosenbaum SH. Not Much Novel Under the Sun. Science 2009, 326: 1480-1481. PMID: 20007882, DOI: 10.1126/science.326.5959.1480-c.
- Surgical demand time variance: a possible explanation for lunar effects and some other mysterious cycles.Schonberger RB. Surgical demand time variance: a possible explanation for lunar effects and some other mysterious cycles. Anesthesiology 2009, 111: 204; author reply 204. PMID: 19546697, DOI: 10.1097/ALN.0b013e3181a8601a.
- Topical non-iontophoretic application of acetylcholine and nitroglycerin via a translucent patch: a new means for assessing microvascular reactivity.Schonberger RB, Worden WS, Shahmohammadi K, Menn K, Silverman TJ, Stout RG, Shelley KH, Silverman DG. Topical non-iontophoretic application of acetylcholine and nitroglycerin via a translucent patch: a new means for assessing microvascular reactivity. The Yale Journal Of Biology And Medicine 2006, 79: 1-7. PMID: 17876370, PMCID: PMC1942174.
- Severe extrapyramidal symptoms in a 3-year-old boy after accidental ingestion of the new antipsychotic drug aripiprazole.Schonberger RB, Douglas L, Baum CR. Severe extrapyramidal symptoms in a 3-year-old boy after accidental ingestion of the new antipsychotic drug aripiprazole. Pediatrics 2004, 114: 1743. PMID: 15574656, DOI: 10.1542/peds.2004-1268.
Clinical Trials
Conditions | Study Title |
---|---|
Diseases of the Cardiovascular System; Pain Control | PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients (PANDORA) |