Jinlei Li, MD, PhD
Research & Publications
Biography
News
Research Summary
Dr. Jinlei Li performs the majority of her clinical research in the subspecialty of regional anesthesiology, where she manages the acute and subacute pain for patients after a diverse range of surgical procedures. Specifically, Dr. Li has directed her efforts on optimizing the roles of regional anesthesia in early recovery after surgery (ERAS) with the aims to reduce opioid consumption, lessen length of hospital stay and improve surgical outcome. She has designed and implemented several institutional level protocols and serves as the PI for Yale RCT trial, as well as site PI for multiple international multicenter trials.
Extensive Research Description
Roles of regional anesthesia in geriatric hip fracture pain management and outcome
Optimization of postoperative pain management with novel regional anesthesia protocols in total knee arthroplasty
Optimization of postoperative pain management with novel regional anesthesia protocols in total hip arthroplasty
Choice of local anesthetic adjuvants in acute and subacute pain management as well as opioid reduction before and after patients’ discharge
Truncal nerve blockade for chest and abdominal procedures
Regional anesthesia and pain management for spine surgery
ERAS for breast surgery
Coauthors
Research Images
Selected Publications
- Bedside Peripheral Nerve Blockade: OverviewBurzynski A, Li J. Bedside Peripheral Nerve Blockade: Overview. 2022, 45-55. DOI: 10.1007/978-3-031-11188-4_6.
- Full title: The prevalence of and predictors for perioperative hypothermia in postanaesthesia care unit.Zhang H, Wang J, Zhu S, Li J. Full title: The prevalence of and predictors for perioperative hypothermia in postanaesthesia care unit. Journal Of Clinical Nursing 2022, 31: 2584-2592. PMID: 34750903, DOI: 10.1111/jocn.16080.
- Understanding fascial anatomy and interfascial communication: implications in regional anesthesia.Shao P, Li H, Shi R, Li J, Wang Y. Understanding fascial anatomy and interfascial communication: implications in regional anesthesia. Journal Of Anesthesia 2022, 36: 554-563. PMID: 35697947, DOI: 10.1007/s00540-022-03082-3.
- Perineural Methylprednisolone Depot Formulation Decreases Opioid Consumption After Total Knee ArthroplastyDel Toro-Pagán NM, Dai F, Banack T, Berlin J, Makadia SA, Rubin LE, Zhou B, Huynh P, Li J. Perineural Methylprednisolone Depot Formulation Decreases Opioid Consumption After Total Knee Arthroplasty. Journal Of Pain Research 2022, 15: 2537-2546. PMID: 36061486, PMCID: PMC9432382, DOI: 10.2147/jpr.s378243.
- Pain, Analgesic Use, and Patient Satisfaction With Spinal Versus General Anesthesia for Hip Fracture Surgery : A Randomized Clinical Trial.Neuman MD, Feng R, Ellenberg SS, Sieber F, Sessler DI, Magaziner J, Elkassabany N, Schwenk ES, Dillane D, Marcantonio ER, Menio D, Ayad S, Hassan M, Stone T, Papp S, Donegan D, Marshall M, Jaffe JD, Luke C, Sharma B, Azim S, Hymes R, Chin KJ, Sheppard R, Perlman B, Sappenfield J, Hauck E, Hoeft MA, Tierney A, Gaskins LJ, Horan AD, Brown T, Dattilo J, Carson JL, Looke T, Bent S, Franco-Mora A, Hedrick P, Newbern M, Tadros R, Pealer K, Vlassakov K, Buckley C, Gavin L, Gorbatov S, Gosnell J, Steen T, Vafai A, Zeballos J, Hruslinski J, Cardenas L, Berry A, Getchell J, Quercetti N, Bajracharya G, Billow D, Bloomfield M, Cuko E, Elyaderani MK, Hampton R, Honar H, Khoshknabi D, Kim D, Krahe D, Lew MM, Maheshwer CB, Niazi A, Saha P, Salih A, de Swart RJ, Volio A, Bolkus K, DeAngelis M, Dodson G, Gerritsen J, McEniry B, Mitrev L, Kwofie MK, Belliveau A, Bonazza F, Lloyd V, Panek I, Dabiri J, Chavez C, Craig J, Davidson T, Dietrichs C, Fleetwood C, Foley M, Getto C, Hailes S, Hermes S, Hooper A, Koener G, Kohls K, Law L, Lipp A, Losey A, Nelson W, Nieto M, Rogers P, Rutman S, Scales G, Sebastian B, Stanciu T, Lobel G, Giampiccolo M, Herman D, Kaufman M, Murphy B, Pau C, Puzio T, Veselsky M, Apostle K, Boyer D, Fan BC, Lee S, Lemke M, Merchant R, Moola F, Payne K, Perey B, Viskontas D, Poler M, D'Antonio P, O'Neill G, Abdullah A, Fish-Fuhrmann J, Giska M, Fidkowski C, Guthrie ST, Hakeos W, Hayes L, Hoegler J, Nowak K, Beck J, Cuff J, Gaski G, Haaser S, Holzman M, Malekzadeh AS, Ramsey L, Schulman J, Schwartzbach C, Azefor T, Davani A, Jaberi M, Masear C, Haider SB, Chungu C, Ebrahimi A, Fikry K, Marcantonio A, Shelvan A, Sanders D, Clarke C, Lawendy A, Schwartz G, Garg M, Kim J, Caruci J, Commeh E, Cuevas R, Cuff G, Franco L, Furgiuele D, Giuca M, Allman M, Barzideh O, Cossaro J, D'Arduini A, Farhi A, Gould J, Kafel J, Patel A, Peller A, Reshef H, Safur M, Toscano F, Tedore T, Akerman M, Brumberger E, Clark S, Friedlander R, Jegarl A, Lane J, Lyden JP, Mehta N, Murrell MT, Painter N, Ricci W, Sbrollini K, Sharma R, Steel PAD, Steinkamp M, Weinberg R, Wellman DS, Nader A, Fitzgerald P, Ritz M, Bryson G, Craig A, Farhat C, Gammon B, Gofton W, Harris N, Lalonde K, Liew A, Meulenkamp B, Sonnenburg K, Wai E, Wilkin G, Troxell K, Alderfer ME, Brannen J, Cupitt C, Gerhart S, McLin R, Sheidy J, Yurick K, Chen F, Dragert K, Kiss G, Malveaux H, McCloskey D, Mellender S, Mungekar SS, Noveck H, Sagebien C, Biby L, McKelvy G, Richards A, Abola R, Ayala B, Halper D, Mavarez A, Rizwan S, Choi S, Awad I, Flynn B, Henry P, Jenkinson R, Kaustov L, Lappin E, McHardy P, Singh A, Donnelly J, Gonzalez M, Haydel C, Livelsberger J, Pazionis T, Slattery B, Vazquez-Trejo M, Baratta J, Cirullo M, Deiling B, Deschamps L, Glick M, Katz D, Krieg J, Lessin J, Mojica J, Torjman M, Jin R, Salpeter MJ, Powell M, Simmons J, Lawson P, Kukreja P, Graves S, Sturdivant A, Bryant A, Crump SJ, Verrier M, Green J, Menon M, Applegate R, Arias A, Pineiro N, Uppington J, Wolinsky P, Gunnett A, Hagen J, Harris S, Hollen K, Holloway B, Horodyski MB, Pogue T, Ramani R, Smith C, Woods A, Warrick M, Flynn K, Mongan P, Ranganath Y, Fernholz S, Ingersoll-Weng E, Marian A, Seering M, Sibenaller Z, Stout L, Wagner A, Walter A, Wong C, Orwig D, Goud M, Helker C, Mezenghie L, Montgomery B, Preston P, Schwartz JS, Weber R, Fleisher LA, Mehta S, Stephens-Shields AJ, Dinh C, Chelly JE, Goel S, Goncz W, Kawabe T, Khetarpal S, Monroe A, Shick V, Breidenstein M, Dominick T, Friend A, Mathews D, Lennertz R, Sanders R, Akere H, Balweg T, Bo A, Doro C, Goodspeed D, Lang G, Parker M, Rettammel A, Roth M, White M, Whiting P, Allen BFS, Baker T, Craven D, McEvoy M, Turnbo T, Kates S, Morgan M, Willoughby T, Weigel W, Auyong D, Fox E, Welsh T, Cusson B, Dobson S, Edwards C, Harris L, Henshaw D, Johnson K, McKinney G, Miller S, Reynolds J, Segal BS, Turner J, VanEenenaam D, Weller R, Lei J, Treggiari M, Akhtar S, Blessing M, Johnson C, Kampp M, Kunze K, O'Connor M, Looke T, Tadros R, Vlassakov K, Cardenas L, Bolkus K, Mitrev L, Kwofie MK, Dabiri J, Lobel G, Poler M, Giska M, Sanders D, Schwartz G, Giuca M, Tedore T, Nader A, Bryson G, Troxell K, Kiss G, Choi S, Powell M, Applegate R, Warrick M, Ranganath Y, Chelly JE, Lennertz R, Sanders R, Allen BFS, Kates S, Weigel W, Li J, Wijeysundera DN, Kheterpal S, Moore RH, Smith AK, Tosi LL, Looke T, Mehta S, Fleisher L, Hruslinski J, Ramsey L, Langlois C, Mezenghie L, Montgomery B, Oduwole S, Rose T. Pain, Analgesic Use, and Patient Satisfaction With Spinal Versus General Anesthesia for Hip Fracture Surgery : A Randomized Clinical Trial. Annals Of Internal Medicine 2022, 175: 952-960. PMID: 35696684, DOI: 10.7326/M22-0320.
- Postdural Puncture Headache—Risks and Current TreatmentLi H, Wang Y, Oprea AD, Li J. Postdural Puncture Headache—Risks and Current Treatment. Current Pain And Headache Reports 2022, 26: 441-452. PMID: 35353358, DOI: 10.1007/s11916-022-01041-x.
- Glucocorticoid minimizes local anesthetic infusion requirement through adductor canal block and improves perioperative prosthetic joint range of motion in total knee arthroplastyBaldev K, Dai F, Barrett C, Zhou B, Shah M, Howie B, Boominathan P, Zhao X, Li J. Glucocorticoid minimizes local anesthetic infusion requirement through adductor canal block and improves perioperative prosthetic joint range of motion in total knee arthroplasty. PLOS ONE 2022, 17: e0261949. PMID: 35081134, PMCID: PMC8791457, DOI: 10.1371/journal.pone.0261949.
- Spinal Anesthesia or General Anesthesia for Hip Surgery in Older Adults.Neuman MD, Feng R, Carson JL, Gaskins LJ, Dillane D, Sessler DI, Sieber F, Magaziner J, Marcantonio ER, Mehta S, Menio D, Ayad S, Stone T, Papp S, Schwenk ES, Elkassabany N, Marshall M, Jaffe JD, Luke C, Sharma B, Azim S, Hymes RA, Chin KJ, Sheppard R, Perlman B, Sappenfield J, Hauck E, Hoeft MA, Giska M, Ranganath Y, Tedore T, Choi S, Li J, Kwofie MK, Nader A, Sanders RD, Allen BFS, Vlassakov K, Kates S, Fleisher LA, Dattilo J, Tierney A, Stephens-Shields AJ, Ellenberg SS. Spinal Anesthesia or General Anesthesia for Hip Surgery in Older Adults. The New England Journal Of Medicine 2021, 385: 2025-2035. PMID: 34623788, DOI: 10.1056/NEJMoa2113514.
- Transmuscular Quadratus Lumborum Block in Total Hip ReplacementLi J, Dai F, Schonberger RB. Transmuscular Quadratus Lumborum Block in Total Hip Replacement. The Clinical Journal Of Pain 2021, 37: 940-941. PMID: 34757344, DOI: 10.1097/ajp.0000000000000984.
- Erector Spinae Plane Block for Perioperative Pain Control and Short-term Outcomes in Lumbar Laminoplasty: A Randomized Clinical TrialJin Y, Zhao S, Cai J, Blessing M, Zhao X, Tan H, Li J. Erector Spinae Plane Block for Perioperative Pain Control and Short-term Outcomes in Lumbar Laminoplasty: A Randomized Clinical Trial. Journal Of Pain Research 2021, 14: 2717-2727. PMID: 34512011, PMCID: PMC8423490, DOI: 10.2147/jpr.s321514.
- Ultrasound Guided Brachial Plexus BlockLi J, Sharma A, Credaroli E, Vadivelu N, Liu H. Ultrasound Guided Brachial Plexus Block. 2021, 121-128. DOI: 10.1007/978-3-030-46839-2_13.
- Transmuscular Quadratus Lumborum and Lateral Femoral Cutaneous Nerve Block in Total Hip ArthroplastyLi J, Dai F, Ayala K, Zhou B, Schonberger RB, Sharma A. Transmuscular Quadratus Lumborum and Lateral Femoral Cutaneous Nerve Block in Total Hip Arthroplasty. The Clinical Journal Of Pain 2021, 37: 366-371. PMID: 33577193, PMCID: PMC8035232, DOI: 10.1097/ajp.0000000000000923.
- A single-operator technique in ultrasound-guided regional anesthesiaTang S, Li JL, Zhang YG, Huang YG. A single-operator technique in ultrasound-guided regional anesthesia. Chinese Medical Journal 2020, 134: 734-735. PMID: 33109955, PMCID: PMC7990013, DOI: 10.1097/cm9.0000000000001186.
- Ultrasound-Guided Neuraxial AnesthesiaLi J, Krishna R, Zhang Y, Lam D, Vadivelu N. Ultrasound-Guided Neuraxial Anesthesia. Current Pain And Headache Reports 2020, 24: 59. PMID: 32812182, DOI: 10.1007/s11916-020-00895-3.
- Periprocedural management of patients on oral anticoagulation: focus on regional anesthesia.Li J, Oprea AD. Periprocedural management of patients on oral anticoagulation: focus on regional anesthesia. Polish Archives Of Internal Medicine 2020, 130: 1081-1092. PMID: 32491305, DOI: 10.20452/pamw.15416.
- Minimum effective dose of plain bupivacaine 0.5% for ultrasound-guided spinal anaesthesia using Taylor's approach.Liu Y, Yang S, Yao W, Zhang S, Wang S, Li J, Mei W. Minimum effective dose of plain bupivacaine 0.5% for ultrasound-guided spinal anaesthesia using Taylor's approach. British Journal Of Anaesthesia 2020, 124: e230-e231. PMID: 32252980, DOI: 10.1016/j.bja.2020.03.008.
- Integrated Fragility Hip Fracture Program: A Model for High Quality CareMorris JC, Moore A, Kahan J, Shapiro M, Li J, Spadaccino B, Baumgaertner M, O'Connor MI. Integrated Fragility Hip Fracture Program: A Model for High Quality Care. Journal Of Hospital Medicine 2020, 15: 461-467. PMID: 32118555, DOI: 10.12788/jhm.3365.
- Regional anesthesia considerations for cardiac surgery.Liu H, Emelife PI, Prabhakar A, Moll V, Kendrick JB, Parr AT, Hyatali F, Pankaj T, Li J, Cornett EM, Urman RD, Fox CJ, Kaye AD. Regional anesthesia considerations for cardiac surgery. Best Practice & Research. Clinical Anaesthesiology 2019, 33: 387-406. PMID: 31791558, DOI: 10.1016/j.bpa.2019.07.008.
- Complications and liability related to regional and neuraxial anesthesia.Liu H, Brown M, Sun L, Patel SP, Li J, Cornett EM, Urman RD, Fox CJ, Kaye AD. Complications and liability related to regional and neuraxial anesthesia. Best Practice & Research. Clinical Anaesthesiology 2019, 33: 487-497. PMID: 31791565, DOI: 10.1016/j.bpa.2019.07.007.
- A Breast Cancer Survivor’s Self-Controlled Case Report: Methylprednisolone Acetate Provided a Week Longer Analgesia Than Dexamethasone Sodium Phosphate via Thoracic Paravertebral BlockadeLi J, Lee K, Chang D, Boominathan P, Banack T. A Breast Cancer Survivor’s Self-Controlled Case Report: Methylprednisolone Acetate Provided a Week Longer Analgesia Than Dexamethasone Sodium Phosphate via Thoracic Paravertebral Blockade. Cureus 2019, 11: e6085. PMID: 31853436, PMCID: PMC6894892, DOI: 10.7759/cureus.6085.
- Paravertebral Block with Compound Betamethasone in Laparoscopic Cholecystectomy: A Double-blind Randomized Controlled TrialLi J, Li L, Zhang X, Li C, He D, Zhang J, Duan C, Perese F, Burzynski A, Wu CL, Dai F, Xue Y. Paravertebral Block with Compound Betamethasone in Laparoscopic Cholecystectomy: A Double-blind Randomized Controlled Trial. Cureus 2019, 11: e6023. PMID: 31824791, PMCID: PMC6886661, DOI: 10.7759/cureus.6023.
- Perioperative Dextrose Infusion and Postoperative Nausea and VomitingZorrilla-Vaca A, Marmolejo-Posso D, Stone A, Li J, Grant MC. Perioperative Dextrose Infusion and Postoperative Nausea and Vomiting. Anesthesia & Analgesia 2019, Publish Ahead of Print: &na;. PMID: 30649067, DOI: 10.1213/ane.0000000000004019.
- Essential elements of an outpatient total joint replacement programme.Li J, Rubin LE, Mariano ER. Essential elements of an outpatient total joint replacement programme. Current Opinion In Anaesthesiology 2019, 32: 643-648. PMID: 31356361, DOI: 10.1097/aco.0000000000000774.
- Novel Regional Anesthesia for Outpatient SurgeryLi J, Lam D, King H, Credaroli E, Harmon E, Vadivelu N. Novel Regional Anesthesia for Outpatient Surgery. Current Pain And Headache Reports 2019, 23: 69. PMID: 31372836, DOI: 10.1007/s11916-019-0809-6.
- Novel utilization of fascial layer blocks in hip and knee proceduresLi J, Tang S, Lam D, Hergrueter A, Dennis J, Liu H. Novel utilization of fascial layer blocks in hip and knee procedures. Best Practice & Research Clinical Anaesthesiology 2019, 33: 539-551. PMID: 31791569, DOI: 10.1016/j.bpa.2019.07.010.
- Tourniquet-induced tissue hypoxia characterized by near-infrared spectroscopy during ankle surgery: an observational studyLin L, Li G, Li J, Meng L. Tourniquet-induced tissue hypoxia characterized by near-infrared spectroscopy during ankle surgery: an observational study. BMC Anesthesiology 2019, 19: 70. PMID: 31077128, PMCID: PMC6511202, DOI: 10.1186/s12871-019-0740-8.
- A Practical Analgesia Approach to Fragility Hip FractureLi J, Dai F, Chang D, Harmon E, Ibe I, Sukumar N, Halaszynski TM, Rubin LE, OʼConnor M. A Practical Analgesia Approach to Fragility Hip Fracture. Journal Of Orthopaedic Trauma 2019, Publish Ahead of Print: &na;. PMID: 30570615, DOI: 10.1097/bot.0000000000001391.
- Effective Pain Management After Total Hip Arthroplasty in a Sickle Cell Patient Emphasizing Dexamethasone Sodium Phosphate/Methylprednisolone Acetate Administered via a Peripheral Nerve Blockade: A Case Report.Li J, Perese F, Rubin LE, Carlyle D. Effective Pain Management After Total Hip Arthroplasty in a Sickle Cell Patient Emphasizing Dexamethasone Sodium Phosphate/Methylprednisolone Acetate Administered via a Peripheral Nerve Blockade: A Case Report. A&A Practice 2019, 12: 171-175. PMID: 30153113, DOI: 10.1213/XAA.0000000000000877.
- The Principles and Procedures of Ultrasound-guided Anesthesia TechniquesHuang J, Li J, Wang H. The Principles and Procedures of Ultrasound-guided Anesthesia Techniques. Cureus 2018, 10: e2980. PMID: 30237941, PMCID: PMC6141058, DOI: 10.7759/cureus.2980.
- The role of sciatic nerve block to complement femoral nerve block in total knee arthroplasty: a meta-analysis of randomized controlled trialsZorrilla-Vaca A, Li J. The role of sciatic nerve block to complement femoral nerve block in total knee arthroplasty: a meta-analysis of randomized controlled trials. Journal Of Anesthesia 2018, 32: 341-350. PMID: 29520522, DOI: 10.1007/s00540-018-2480-1.
- Dexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve BlocksZorrilla-Vaca A, Li J. Dexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve Blocks. The Clinical Journal Of Pain 2018, 34: 276-284. PMID: 28591086, DOI: 10.1097/ajp.0000000000000519.
- Incidental lumbar epidural catheter migration through a sacral foramen and its subsequent direct visualization during surgeryChang D, Legler A, Jolly S, Li J. Incidental lumbar epidural catheter migration through a sacral foramen and its subsequent direct visualization during surgery. Journal Of Clinical Anesthesia 2018, 46: 52-53. PMID: 29414617, DOI: 10.1016/j.jclinane.2018.01.017.
- Dexmedetomidine Added to Local Anesthetic Mixture of Lidocaine and Ropivacaine Enhances Onset and Prolongs Duration of a Popliteal Approach to Sciatic Nerve BlockadeHu X, Li J, Zhou R, Wang Q, Xia F, Halaszynski T, Xu X. Dexmedetomidine Added to Local Anesthetic Mixture of Lidocaine and Ropivacaine Enhances Onset and Prolongs Duration of a Popliteal Approach to Sciatic Nerve Blockade. Clinical Therapeutics 2016, 39: 89-97.e1. PMID: 27955918, DOI: 10.1016/j.clinthera.2016.11.011.
- Regional Analgesia for Orthopedic SurgeryFoldes P, Doty J, Li J. Regional Analgesia for Orthopedic Surgery. 2016, 37-42. DOI: 10.1007/978-3-319-34109-5_6.
- The Impact of Neuraxial Versus General Anesthesia on the Incidence of Postoperative Surgical Site Infections Following Knee or Hip ArthroplastyZorrilla-Vaca A, Grant MC, Mathur V, Li J, Wu CL. The Impact of Neuraxial Versus General Anesthesia on the Incidence of Postoperative Surgical Site Infections Following Knee or Hip Arthroplasty. Regional Anesthesia & Pain Medicine 2016, 41: 555-563. PMID: 27380106, DOI: 10.1097/aap.0000000000000437.
- Neuraxial and peripheral nerve blocks in patients taking anticoagulant or thromboprophylactic drugs: challenges and solutionsLi J, Halaszynski T. Neuraxial and peripheral nerve blocks in patients taking anticoagulant or thromboprophylactic drugs: challenges and solutions. Local And Regional Anesthesia 2015, Volume 8: 21-32. PMID: 26347411, PMCID: PMC4531015, DOI: 10.2147/lra.s55306.
- Regional Analgesia for Orthopedic SurgeryFoldes P, Doty J, Li J. Regional Analgesia for Orthopedic Surgery. 2015, 1-6. DOI: 10.1007/978-3-319-15206-6_6-1.
- Regional anesthesia for acute pain management in elderly patientsLi J, Halaszynski TM. World J Anesthesiol 2014; 3(1): 82-95
- TrazodoneLi J. Trazodone. 2010, 351-352. DOI: 10.1017/cbo9780511841378.086.
- Two Trypanosome-Specific Proteins Are Essential Factors for 5S rRNA Abundance and Ribosomal Assembly in Trypanosoma brucei▿Hellman KM, Ciganda M, Brown SV, Li J, Ruyechan W, Williams N. Two Trypanosome-Specific Proteins Are Essential Factors for 5S rRNA Abundance and Ribosomal Assembly in Trypanosoma brucei▿. MSphere 2007, 6: 1766-1772. PMID: 17715362, PMCID: PMC2043393, DOI: 10.1128/ec.00119-07.
- ATP Synthase Is Responsible for Maintaining Mitochondrial Membrane Potential in Bloodstream Form Trypanosoma bruceiBrown SV, Hosking P, Li J, Williams N. ATP Synthase Is Responsible for Maintaining Mitochondrial Membrane Potential in Bloodstream Form Trypanosoma brucei. MSphere 2006, 5: 45-53. PMID: 16400167, PMCID: PMC1360250, DOI: 10.1128/ec.5.1.45-53.2006.
- Stage-specific translational efficiency and protein stability regulate the developmental expression of p37, an RNA binding protein from Trypanosoma bruceiLi J, Ruyechan WT, Williams N. Stage-specific translational efficiency and protein stability regulate the developmental expression of p37, an RNA binding protein from Trypanosoma brucei. Biochemical And Biophysical Research Communications 2003, 306: 918-923. PMID: 12821129, DOI: 10.1016/s0006-291x(03)01084-2.
Clinical Trials
Conditions | Study Title |
---|---|
Arthritis; Diseases of the Musculoskeletal System | Opioid-Sparing Protocol Comparing With Opioid-based Protocol After Bilateral Total Knee Arthroplasty |