Peter Morgan, MD, PhD
Professor of Clinical Psychiatry; Chair, Bridgeport Hospital, Department of Psychiatry
Research & Publications
Biography
News
Research Summary
I am interested in the neurophysiology of substance dependence for its own sake and as a window into understanding cognition and behavior. The major focus of my laboratory is the examination of the role of disturbances of sleep and sleep-dependent memory consolidation in chronic substance use and other mental illnesses. My laboratory has found that abstinent male cocaine users suffer from an "occult" insomnia. Although their sleep is objectively poor and they exhibit cognitive disruptions related to this poor sleep, they believe that their sleep is unimpaired.
Recent findings suggest that modafinil, a wakefulness promoting agent, reverses some of the sleep deficits associated with chronic cocaine use.
Recent findings suggest that modafinil, a wakefulness promoting agent, reverses some of the sleep deficits associated with chronic cocaine use.
Extensive Research Description
My recent and current human subject studies have examined sleep and learning in cocaine dependence and the relevance of GABA neurotransmission thereon, and have sought neurophysiological markers of alcohol craving. Experimental tools used include EEG/ERP, polysomnography (PSG), cocaine self-administration, neuroimaging, and a variety of standard and newly developed cognitive tasks including visual, motor, and verbal learning tasks, as well tasks of attention and memory.
Another project examines lucid dreaming and what differentiates lucid dreamers from non-lucid dreamers in terms of brain function. This project is directed at understanding the brain processes that lead to different types of consciousness.
Another project examines lucid dreaming and what differentiates lucid dreamers from non-lucid dreamers in terms of brain function. This project is directed at understanding the brain processes that lead to different types of consciousness.
Coauthors
Research Interests
Behavior and Behavior Mechanisms; Sleep Wake Disorders; Substance-Related Disorders
Selected Publications
- P.499 Ketamine's influence on global resting-state functional connectivity and individual variation in neuro-behavioural relationshipsMoujaes F, Preller K, Vollenweider F, Schleifer C, Adkinson B, Kolobaric A, Fineberg S, Krystal J, Repovs G, Santamauro N, Morgan P, Savic A, Cho Y, D. M, Anticevic A. P.499 Ketamine's influence on global resting-state functional connectivity and individual variation in neuro-behavioural relationships European Neuropsychopharmacology 2020, 40: s278-s279. DOI: 10.1016/j.euroneuro.2020.09.363.
- S159. NMDA Receptor Antagonism Effects on Delayed Spatial Working Memory and Distraction in Comparison With SchizophreniaMoujaes F, Preller K, Vollenweider F, Schleifer C, Ji J, Adkinson B, Kolobaric A, Flynn M, Fineberg S, Krystal J, Repovs G, Santamauro N, Morgan P, Savic A, Cho Y, Murray J, Anticevic A. S159. NMDA Receptor Antagonism Effects on Delayed Spatial Working Memory and Distraction in Comparison With Schizophrenia Biological Psychiatry 2019, 85: s358. DOI: 10.1016/j.biopsych.2019.03.910.
- F195. NMDAR Antagonism via Ketamine Differentially Modulates Thalamic Versus Hippocampal Brain-Wide Functional ConnectivityMoujaes F, Schleifer C, Ji L, Adkinson B, Kolobaric A, Flynn M, Fineberg S, Krystal J, Repovs G, Cho Y, Santamauro N, Morgan P, Savic A, Murray J, Anticevic A. F195. NMDAR Antagonism via Ketamine Differentially Modulates Thalamic Versus Hippocampal Brain-Wide Functional Connectivity Biological Psychiatry 2019, 85: s289. DOI: 10.1016/j.biopsych.2019.03.732.
- Efficacy and safety of a fatty acid amide hydrolase inhibitor (PF-04457845) in the treatment of cannabis withdrawal and dependence in men: a double-blind, placebo-controlled, parallel group, phase 2a single-site randomised controlled trialD'Souza DC, Cortes-Briones J, Creatura G, Bluez G, Thurnauer H, Deaso E, Bielen K, Surti T, Radhakrishnan R, Gupta A, Gupta S, Cahill J, Sherif MA, Makriyannis A, Morgan PT, Ranganathan M, Skosnik PD. Efficacy and safety of a fatty acid amide hydrolase inhibitor (PF-04457845) in the treatment of cannabis withdrawal and dependence in men: a double-blind, placebo-controlled, parallel group, phase 2a single-site randomised controlled trial The Lancet Psychiatry 2018, 6: 35-45. PMID: 30528676, DOI: 10.1016/s2215-0366(18)30427-9.
- The Barriers and Benefits to Developing Forensic Rotations for Psychiatry Residents.Michaelsen KC, Lewis AS, Morgan PT, McKee SA, Wasser TD. The Barriers and Benefits to Developing Forensic Rotations for Psychiatry Residents. The Journal Of The American Academy Of Psychiatry And The Law 2018, 46: 322-328. PMID: 30368464, DOI: 10.29158/jaapl.003766-18.
- 165. Modulation of Sleep and Circadian Rhythm in the Treatment of Cocaine Use DisorderMorgan P. 165. Modulation of Sleep and Circadian Rhythm in the Treatment of Cocaine Use Disorder Biological Psychiatry 2018, 83: s67. DOI: 10.1016/j.biopsych.2018.02.183.
- 92. Using Pharmacological Neuroimaging to Understand Microcircuit E/I Imbalance in HumansAnticevic A, Schleifer C, Adkinson B, Cho Y, Morgan P, Savic A, Demirtas M, Ji J, Murray J. 92. Using Pharmacological Neuroimaging to Understand Microcircuit E/I Imbalance in Humans Biological Psychiatry 2018, 83: s38. DOI: 10.1016/j.biopsych.2018.02.109.
- 168. The Effect of Fatty Acid Amide Hydrolase Inhibition on Sleep Architecture in Cannabis WithdrawalSkosnik P, Cortes-Briones J, Creatura G, Morgan P, Ranganathan M, Deaso E, Surti T, D'Souza D. 168. The Effect of Fatty Acid Amide Hydrolase Inhibition on Sleep Architecture in Cannabis Withdrawal Biological Psychiatry 2018, 83: s68. DOI: 10.1016/j.biopsych.2018.02.186.
- Ketamine and Sleep: Bridging the Gap in the Treatment of Depressive IllnessMorgan PT. Ketamine and Sleep: Bridging the Gap in the Treatment of Depressive Illness Biological Psychiatry 2017, 82: 309-311. PMID: 28781004, DOI: 10.1016/j.biopsych.2017.07.005.
- 399 Ketamine and Guanfacine Effects on Activation and Connectivity during Working Memory: A Functional Magnetic Resonance Imaging InvestigationDriesen N, McCarthy G, Arnsten A, Morgan P, He G, Bloch M, Krystal J. 399 Ketamine and Guanfacine Effects on Activation and Connectivity during Working Memory: A Functional Magnetic Resonance Imaging Investigation Biological Psychiatry 2017, 81: s163. DOI: 10.1016/j.biopsych.2017.02.416.
- 423 NMDAR Antagonism via Ketamine Differentially Modulates Thalamic versus Hippocampal Functional ConnectivityAnticevic A, Schleifer C, Srihari V, Krystal J, Murray J, Repovs G, Xu G, Ji L, Cho Y, Santamauro N, Foss-Feig J, Yang G, Morgan P, Savic A. 423 NMDAR Antagonism via Ketamine Differentially Modulates Thalamic versus Hippocampal Functional Connectivity Biological Psychiatry 2017, 81: s172-s173. DOI: 10.1016/j.biopsych.2017.02.907.
- Computerized Cognitive Behavioral Therapy for Insomnia in a Community Health Setting.Feuerstein S, Hodges SE, Keenaghan B, Bessette A, Forselius E, Morgan PT. Computerized Cognitive Behavioral Therapy for Insomnia in a Community Health Setting. Journal Of Clinical Sleep Medicine 2017, 13: 267-274. PMID: 27784409, PMCID: PMC5263082, DOI: 10.5664/jcsm.6460.
- Sleep Perception and Misperception in Chronic Cocaine Users During Abstinence.Hodges SE, Pittman B, Morgan PT. Sleep Perception and Misperception in Chronic Cocaine Users During Abstinence. Sleep 2016, 40 PMID: 28364419, PMCID: PMC5806585, DOI: 10.1093/sleep/zsw069.
- Schizophrenia is associated with a pattern of spatial working memory deficits consistent with cortical disinhibitionStarc M, Murray JD, Santamauro N, Savic A, Diehl C, Cho YT, Srihari V, Morgan PT, Krystal JH, Wang XJ, Repovs G, Anticevic A. Schizophrenia is associated with a pattern of spatial working memory deficits consistent with cortical disinhibition Schizophrenia Research 2016, 181: 107-116. PMID: 27745755, PMCID: PMC5901719, DOI: 10.1016/j.schres.2016.10.011.
- Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive reviewAngarita GA, Emadi N, Hodges S, Morgan PT. Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review Addiction Science & Clinical Practice 2016, 11: 9. PMID: 27117064, PMCID: PMC4845302, DOI: 10.1186/s13722-016-0056-7.
- Modafinil and sleep architecture in an inpatient–outpatient treatment study of cocaine dependenceMorgan PT, Angarita GA, Canavan S, Pittman B, Oberleitner L, Malison RT, Mohsenin V, Hodges S, Easton C, McKee S, Bessette A, Forselius E. Modafinil and sleep architecture in an inpatient–outpatient treatment study of cocaine dependence Drug And Alcohol Dependence 2016, 160: 49-56. PMID: 26777774, PMCID: PMC4767553, DOI: 10.1016/j.drugalcdep.2015.12.004.
- Chapter 21 Sleep and CocaineAngarita G, Canavan S, Hodges S, Morgan P. Chapter 21 Sleep and Cocaine 2016, 220-228. DOI: 10.1016/b978-0-12-800212-4.00021-2.
- Association of Cigarette Smoking With Interpersonal and Self-Directed Violence in a Large Community-Based SampleLewis AS, Oberleitner LM, Morgan PT, Picciotto MR, McKee SA. Association of Cigarette Smoking With Interpersonal and Self-Directed Violence in a Large Community-Based Sample Nicotine & Tobacco Research 2015, 18: 1456-1462. PMID: 26718905, PMCID: PMC5942535, DOI: 10.1093/ntr/ntv287.
- Psychosocial and metabolic function by smoking status in individuals with binge eating disorder and obesityUdo T, White MA, Barnes RD, Ivezaj V, Morgan P, Masheb RM, Grilo CM. Psychosocial and metabolic function by smoking status in individuals with binge eating disorder and obesity Addictive Behaviors 2015, 53: 46-52. PMID: 26451703, PMCID: PMC4679522, DOI: 10.1016/j.addbeh.2015.09.018.
- Ketamine-Induced HallucinationsPowers A, Gancsos MG, Finn ES, Morgan PT, Corlett PR. Ketamine-Induced Hallucinations Psychopathology 2015, 48: 376-385. PMID: 26361209, PMCID: PMC4684980, DOI: 10.1159/000438675.
- Effects of endogenous and exogenous progesterone on emotional intelligence in cocaine‐dependent men and women who also abuse alcoholMilivojevic V, Sinha R, Morgan PT, Sofuoglu M, Fox HC. Effects of endogenous and exogenous progesterone on emotional intelligence in cocaine‐dependent men and women who also abuse alcohol Human Psychopharmacology Clinical And Experimental 2014, 29: 589-598. PMID: 25363303, PMCID: PMC4498951, DOI: 10.1002/hup.2446.
- N-Methyl-D-Aspartate Receptor Antagonist Effects on Prefrontal Cortical Connectivity Better Model Early Than Chronic SchizophreniaAnticevic A, Corlett PR, Cole MW, Savic A, Gancsos M, Tang Y, Repovs G, Murray JD, Driesen NR, Morgan PT, Xu K, Wang F, Krystal JH. N-Methyl-D-Aspartate Receptor Antagonist Effects on Prefrontal Cortical Connectivity Better Model Early Than Chronic Schizophrenia Biological Psychiatry 2014, 77: 569-580. PMID: 25281999, DOI: 10.1016/j.biopsych.2014.07.022.
- Correlates of polysomnographic sleep changes in cocaine dependence: Self-administration and clinical outcomesAngarita GA, Canavan SV, Forselius E, Bessette A, Morgan PT. Correlates of polysomnographic sleep changes in cocaine dependence: Self-administration and clinical outcomes Drug And Alcohol Dependence 2014, 143: 173-180. PMID: 25124303, PMCID: PMC4207081, DOI: 10.1016/j.drugalcdep.2014.07.025.
- Dreams, reality and memory: confabulations in lucid dreamers implicate reality-monitoring dysfunction in dream consciousnessCorlett PR, Canavan SV, Nahum L, Appah F, Morgan PT. Dreams, reality and memory: confabulations in lucid dreamers implicate reality-monitoring dysfunction in dream consciousness Cognitive Neuropsychiatry 2014, 19: 540-553. PMID: 25028078, PMCID: PMC4160044, DOI: 10.1080/13546805.2014.932685.
- Paradoxical normalization of risk-taking by modafinil in chronic cocaine usersCanavan S, Forselius E, Bessette A, Morgan P. Paradoxical normalization of risk-taking by modafinil in chronic cocaine users Drug And Alcohol Dependence 2014, 140: e26. DOI: 10.1016/j.drugalcdep.2014.02.092.
- Sleep and clinical outcomes in the placebo arm of a randomized clinical trial of modafinil treatment for cocaine dependenceAngarita G, Canavan S, Forselius E, Bessette A, Pittman B, Morgan P. Sleep and clinical outcomes in the placebo arm of a randomized clinical trial of modafinil treatment for cocaine dependence Drug And Alcohol Dependence 2014, 140: e5. DOI: 10.1016/j.drugalcdep.2014.02.036.
- 5:45 PM INTEGRATING PHARMACOLOGY AND COMPUTATION: TOWARDS UNDERSTANDING MECHANISMS OF COGNITIVE AND CONNECTIVITY DEFICITS IN SCHIZOPHRENIAAnticevic A, Murray J, Repovs G, Starc M, Santamauro N, Savic A, Morgan P, Wang X, Krystal J. 5:45 PM INTEGRATING PHARMACOLOGY AND COMPUTATION: TOWARDS UNDERSTANDING MECHANISMS OF COGNITIVE AND CONNECTIVITY DEFICITS IN SCHIZOPHRENIA Schizophrenia Research 2014, 153: s52-s53. DOI: 10.1016/s0920-9964(14)70172-0.
- Preliminary evidence for normalization of risk taking by modafinil in chronic cocaine usersCanavan SV, Forselius EL, Bessette AJ, Morgan PT. Preliminary evidence for normalization of risk taking by modafinil in chronic cocaine users Addictive Behaviors 2014, 39: 1057-1061. PMID: 24642345, PMCID: PMC4026273, DOI: 10.1016/j.addbeh.2014.02.015.
- Sex Differences in Guanfacine Effects on Drug Craving and Stress Arousal in Cocaine-Dependent IndividualsFox HC, Morgan PT, Sinha R. Sex Differences in Guanfacine Effects on Drug Craving and Stress Arousal in Cocaine-Dependent Individuals Neuropsychopharmacology 2014, 39: 1527-1537. PMID: 24395021, PMCID: PMC3988558, DOI: 10.1038/npp.2014.1.
- Abstinence-related changes in sleep during treatment for cocaine dependenceAngarita GA, Canavan SV, Forselius E, Bessette A, Pittman B, Morgan PT. Abstinence-related changes in sleep during treatment for cocaine dependence Drug And Alcohol Dependence 2013, 134: 343-347. PMID: 24315572, PMCID: PMC4396819, DOI: 10.1016/j.drugalcdep.2013.11.007.
- Methylphenidate remediates error-preceding activation of the default mode brain regions in cocaine-addicted individualsMatuskey D, Luo X, Zhang S, Morgan PT, Abdelghany O, Malison RT, Li CS. Methylphenidate remediates error-preceding activation of the default mode brain regions in cocaine-addicted individuals Psychiatry Research 2013, 214: 116-121. PMID: 23973363, PMCID: PMC3811038, DOI: 10.1016/j.pscychresns.2013.06.009.
- The Impact of NMDA Receptor Blockade on Human Working Memory-Related Prefrontal Function and ConnectivityDriesen NR, McCarthy G, Bhagwagar Z, Bloch MH, Calhoun VD, D'Souza DC, Gueorguieva R, He G, Leung HC, Ramani R, Anticevic A, Suckow RF, Morgan PT, Krystal JH. The Impact of NMDA Receptor Blockade on Human Working Memory-Related Prefrontal Function and Connectivity Neuropsychopharmacology 2013, 38: 2613-2622. PMID: 23856634, PMCID: PMC3828532, DOI: 10.1038/npp.2013.170.
- The effects of exogenous progesterone on drug craving and stress arousal in cocaine dependence: Impact of gender and cue typeFox HC, Sofuoglu M, Morgan PT, Tuit KL, Sinha R. The effects of exogenous progesterone on drug craving and stress arousal in cocaine dependence: Impact of gender and cue type Psychoneuroendocrinology 2013, 38: 1532-1544. PMID: 23374328, PMCID: PMC3772967, DOI: 10.1016/j.psyneuen.2012.12.022.
- Relationship of resting brain hyperconnectivity and schizophrenia-like symptoms produced by the NMDA receptor antagonist ketamine in humansDriesen NR, McCarthy G, Bhagwagar Z, Bloch M, Calhoun V, D'Souza DC, Gueorguieva R, He G, Ramachandran R, Suckow RF, Anticevic A, Morgan PT, Krystal JH. Relationship of resting brain hyperconnectivity and schizophrenia-like symptoms produced by the NMDA receptor antagonist ketamine in humans Molecular Psychiatry 2013, 18: 1199-1204. PMID: 23337947, PMCID: PMC3646075, DOI: 10.1038/mp.2012.194.
- A single-day paradigm of self-regulated human cocaine administrationMatuskey D, Pittman B, Chen JI, Wanyiri J, Nadim H, Jatlow P, Gueorguieva R, Potenza MN, Morgan PT, Bhagwagar Z, Malison RT. A single-day paradigm of self-regulated human cocaine administration Pharmacology Biochemistry And Behavior 2012, 103: 95-101. PMID: 22922558, PMCID: PMC3652339, DOI: 10.1016/j.pbb.2012.08.009.
- NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophreniaAnticevic A, Gancsos M, Murray JD, Repovs G, Driesen NR, Ennis DJ, Niciu MJ, Morgan PT, Surti TS, Bloch MH, Ramani R, Smith MA, Wang XJ, Krystal JH, Corlett PR. NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 16720-16725. PMID: 23012427, PMCID: PMC3478611, DOI: 10.1073/pnas.1208494109.
- Cortical GABA Levels in Primary InsomniaMorgan PT, Pace-Schott EF, Mason GF, Forselius E, Fasula M, Valentine GW, Sanacora G. Cortical GABA Levels in Primary Insomnia Sleep 2012, 35: 807-814. PMID: 22654200, PMCID: PMC3353043, DOI: 10.5665/sleep.1880.
- Night eating in obese treatment‐seeking hispanic patients with and without binge eating disorderGrilo CM, Milsom VA, Morgan PT, White MA. Night eating in obese treatment‐seeking hispanic patients with and without binge eating disorder International Journal Of Eating Disorders 2012, 45: 787-791. PMID: 22407481, PMCID: PMC3378792, DOI: 10.1002/eat.22011.
- Guanfacine effects on stress, drug craving and prefrontal activation in cocaine dependent individuals: preliminary findingsFox HC, Seo D, Tuit K, Hansen J, Kimmerling A, Morgan PT, Sinha R. Guanfacine effects on stress, drug craving and prefrontal activation in cocaine dependent individuals: preliminary findings Journal Of Psychopharmacology 2012, 26: 958-972. PMID: 22234929, PMCID: PMC3694403, DOI: 10.1177/0269881111430746.
- Prazosin Effects on Stress‐ and Cue‐Induced Craving and Stress Response in Alcohol‐Dependent Individuals: Preliminary FindingsFox HC, Anderson GM, Tuit K, Hansen J, Kimmerling A, Siedlarz KM, Morgan PT, Sinha R. Prazosin Effects on Stress‐ and Cue‐Induced Craving and Stress Response in Alcohol‐Dependent Individuals: Preliminary Findings Alcoholism Clinical And Experimental Research 2011, 36: 351-360. PMID: 21919922, PMCID: PMC3243763, DOI: 10.1111/j.1530-0277.2011.01628.x.
- An examination of the food addiction construct in obese patients with binge eating disorderGearhardt AN, White MA, Masheb RM, Morgan PT, Crosby RD, Grilo CM. An examination of the food addiction construct in obese patients with binge eating disorder International Journal Of Eating Disorders 2011, 45: 657-663. PMID: 22684991, PMCID: PMC3375872, DOI: 10.1002/eat.20957.
- Internalized weight bias in obese patients with binge eating disorder: Associations with eating disturbances and psychological functioningDurso LE, Latner JD, White MA, Masheb RM, Blomquist KK, Morgan PT, Grilo CM. Internalized weight bias in obese patients with binge eating disorder: Associations with eating disturbances and psychological functioning International Journal Of Eating Disorders 2011, 45: 423-427. PMID: 21717488, PMCID: PMC3184343, DOI: 10.1002/eat.20933.
- A multistudy analysis of the effects of early cocaine abstinence on sleepMatuskey D, Pittman B, Forselius E, Malison RT, Morgan PT. A multistudy analysis of the effects of early cocaine abstinence on sleep Drug And Alcohol Dependence 2010, 115: 62-66. PMID: 21144676, PMCID: PMC3081928, DOI: 10.1016/j.drugalcdep.2010.10.015.
- Lucid dreaming and ventromedial versus dorsolateral prefrontal task performanceNeider M, Pace-Schott EF, Forselius E, Pittman B, Morgan PT. Lucid dreaming and ventromedial versus dorsolateral prefrontal task performance Consciousness And Cognition 2010, 20: 234-244. PMID: 20829072, PMCID: PMC3026881, DOI: 10.1016/j.concog.2010.08.001.
- Biological markers of the effects of intravenous methylphenidate on improving inhibitory control in cocaine-dependent patientsLi CS, Morgan PT, Matuskey D, Abdelghany O, Luo X, Chang JL, Rounsaville BJ, Ding YS, Malison RT. Biological markers of the effects of intravenous methylphenidate on improving inhibitory control in cocaine-dependent patients Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 14455-14459. PMID: 20660731, PMCID: PMC2922598, DOI: 10.1073/pnas.1002467107.
- Gender‐Related Influences of Parental Alcoholism on the Prevalence of Psychiatric Illnesses: Analysis of the National Epidemiologic Survey on Alcohol and Related ConditionsMorgan PT, Desai RA, Potenza MN. Gender‐Related Influences of Parental Alcoholism on the Prevalence of Psychiatric Illnesses: Analysis of the National Epidemiologic Survey on Alcohol and Related Conditions Alcoholism Clinical And Experimental Research 2010, 34: 1759-1767. PMID: 20645936, PMCID: PMC2950877, DOI: 10.1111/j.1530-0277.2010.01263.x.
- Exploring weight gain in year before treatment for binge eating disorder: A different context for interpreting limited weight losses in treatment studiesBlomquist KK, Barnes RD, White MA, Masheb RM, Morgan PT, Grilo CM. Exploring weight gain in year before treatment for binge eating disorder: A different context for interpreting limited weight losses in treatment studies International Journal Of Eating Disorders 2010, 44: 435-439. PMID: 20635382, PMCID: PMC3010436, DOI: 10.1002/eat.20836.
- Normalizing Effects of Modafinil on Sleep in Chronic Cocaine UsersMorgan PT, Pace-Schott E, Pittman B, Stickgold R, Malison RT. Normalizing Effects of Modafinil on Sleep in Chronic Cocaine Users American Journal Of Psychiatry 2010, 167: 331-340. PMID: 20080983, PMCID: PMC5857958, DOI: 10.1176/appi.ajp.2009.09050613.
- Regulation of cocaine self-administration in humans: Lack of evidence for loading and maintenance phasesAngarita GA, Pittman B, Gueorguieva R, Kalayasiri R, Lynch WJ, Sughondhabirom A, Morgan PT, Malison RT. Regulation of cocaine self-administration in humans: Lack of evidence for loading and maintenance phases Pharmacology Biochemistry And Behavior 2009, 95: 51-55. PMID: 20005893, PMCID: PMC2824073, DOI: 10.1016/j.pbb.2009.12.005.
- Retrograde effects of triazolam and zolpidem on sleep‐dependent motor learning in humansMORGAN PT, KEHNE JH, SPRENGER KJ, MALISON RT. Retrograde effects of triazolam and zolpidem on sleep‐dependent motor learning in humans Journal Of Sleep Research 2009, 19: 157-164. PMID: 19682231, DOI: 10.1111/j.1365-2869.2009.00757.x.
- Sex differences in sleep and sleep-dependent learning in abstinent cocaine usersMorgan PT, Paliwal P, Malison RT, Sinha R. Sex differences in sleep and sleep-dependent learning in abstinent cocaine users Pharmacology Biochemistry And Behavior 2009, 93: 54-58. PMID: 19379771, PMCID: PMC2699445, DOI: 10.1016/j.pbb.2009.04.006.
- CLINICAL STUDY: Subjective responses and cardiovascular effects of self‐administered cocaine in cocaine‐abusing men and womenLynch WJ, Kalayasiri R, Sughondhabirom A, Pittman B, Coric V, Morgan PT, Malison RT. CLINICAL STUDY: Subjective responses and cardiovascular effects of self‐administered cocaine in cocaine‐abusing men and women Addiction Biology 2008, 13: 403-410. PMID: 18782384, PMCID: PMC3690939, DOI: 10.1111/j.1369-1600.2008.00115.x.
- Sleep architecture, cocaine and visual learningMorgan PT, Pace‐Schott E, Sahul ZH, Coric V, Stickgold R, Malison RT. Sleep architecture, cocaine and visual learning Addiction 2008, 103: 1344-1352. PMID: 18855824, PMCID: PMC3690941, DOI: 10.1111/j.1360-0443.2008.02233.x.
- Chest Tightness and Palpitations Associated With Modafinil and Consumption of Free GlutamateMORGAN PT, MALISON RT. Chest Tightness and Palpitations Associated With Modafinil and Consumption of Free Glutamate American Journal Of Psychiatry 2008, 165: 538-538. PMID: 18381922, DOI: 10.1176/appi.ajp.2007.07040717.
- Cocaine Users Differ from Normals on Cognitive Tasks Which Show Poorer Performance During Drug AbstinencePace-Schott EF, Morgan PT, Malison RT, Hart CL, Edgar C, Walker M, Stickgold R. Cocaine Users Differ from Normals on Cognitive Tasks Which Show Poorer Performance During Drug Abstinence The American Journal Of Drug And Alcohol Abuse 2008, 34: 109-121. PMID: 18161649, DOI: 10.1080/00952990701764821.
- Pilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine AbstinenceMorgan PT, Malison RT. Pilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence The American Journal Of Drug And Alcohol Abuse 2008, 34: 692-702. PMID: 18850496, DOI: 10.1080/00952990802308221.
- Cocaine and Sleep: Early AbstinenceMorgan PT, Malison RT. Cocaine and Sleep: Early Abstinence The Scientific World JOURNAL 2007, 7: 223-230. PMID: 17982597, PMCID: PMC5900952, DOI: 10.1100/tsw.2007.209.
- Sex Steroid Hormones, Stress Response, and Drug Craving in Cocaine-Dependent Women: Implications for Relapse SusceptibilitySinha R, Fox H, Hong KI, Sofuoglu M, Morgan PT, Bergquist KT. Sex Steroid Hormones, Stress Response, and Drug Craving in Cocaine-Dependent Women: Implications for Relapse Susceptibility Experimental And Clinical Psychopharmacology 2007, 15: 445-452. PMID: 17924778, DOI: 10.1037/1064-1297.15.5.445.
- Altered levels of sex and stress steroid hormones assessed daily over a 28-day cycle in early abstinent cocaine-dependent femalesFox HC, Hong KA, Paliwal P, Morgan PT, Sinha R. Altered levels of sex and stress steroid hormones assessed daily over a 28-day cycle in early abstinent cocaine-dependent females Psychopharmacology 2007, 195: 527-536. PMID: 17891383, PMCID: PMC2746368, DOI: 10.1007/s00213-007-0936-3.
- Treatment-Resistant DepressionMorgan PT. Treatment-Resistant Depression Journal Of Clinical Psychopharmacology 2007, 27: 313-314. PMID: 17502787, DOI: 10.1097/01.jcp.0000270085.15253.15.
- A paradigm to investigate the regulation of cocaine self-administration in human cocaine users: a randomized trialLynch WJ, Sughondhabirom A, Pittman B, Gueorguieva R, Kalayasiri R, Joshua D, Morgan P, Coric V, Malison RT. A paradigm to investigate the regulation of cocaine self-administration in human cocaine users: a randomized trial Psychopharmacology 2006, 185: 306-314. PMID: 16521032, DOI: 10.1007/s00213-006-0323-5.
- Self-reported paranoia during laboratory “binge” cocaine self-administration in humansKalayasiri R, Sughondhabirom A, Gueorguieva R, Coric V, Lynch WJ, Morgan PT, Cubells JF, Malison RT. Self-reported paranoia during laboratory “binge” cocaine self-administration in humans Pharmacology Biochemistry And Behavior 2006, 83: 249-256. PMID: 16549106, DOI: 10.1016/j.pbb.2006.02.005.
- Sleep, sleep-dependent procedural learning and vigilance in chronic cocaine users: Evidence for occult insomniaMorgan PT, Pace-Schott EF, Sahul ZH, Coric V, Stickgold R, Malison RT. Sleep, sleep-dependent procedural learning and vigilance in chronic cocaine users: Evidence for occult insomnia Drug And Alcohol Dependence 2005, 82: 238-249. PMID: 16260094, DOI: 10.1016/j.drugalcdep.2005.09.014.
- Interneuronal and Peptidergic Control of Motor Pattern Switching in AplysiaMorgan PT, Jing J, Vilim FS, Weiss KR. Interneuronal and Peptidergic Control of Motor Pattern Switching in Aplysia Journal Of Neurophysiology 2002, 87: 49-61. PMID: 11784729, DOI: 10.1152/jn.00438.2001.
- Intrinsic and Extrinsic Modulation of a Single Central Pattern Generating CircuitMorgan P, Perrins R, Lloyd P, Weiss K. Intrinsic and Extrinsic Modulation of a Single Central Pattern Generating Circuit Journal Of Neurophysiology 2000, 84: 1186-1193. PMID: 10979994, DOI: 10.1152/jn.2000.84.3.1186.
- Expression of Kv1.1 delayed rectifier potassium channels in Lec mutant Chinese hamster ovary cell lines reveals a role for sialidation in channel function.Thornhill WB, Wu MB, Jiang X, Wu X, Morgan PT, Margiotta JF. Expression of Kv1.1 delayed rectifier potassium channels in Lec mutant Chinese hamster ovary cell lines reveals a role for sialidation in channel function. The Journal Of Biological Chemistry 1996, 271: 19093-8. PMID: 8702582, DOI: 10.1074/jbc.271.32.19093.
Clinical Trials
Conditions | Study Title |
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Diseases of the Nervous System; Mental Health & Behavioral Research | Teen Brain and Behavior Study |