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Nalini Vadivelu

MBBS, DNB, MD
Professor of Anesthesiology

Contact Information

Nalini Vadivelu, MBBS, DNB, MD

Mailing Address

  • Anesthesiology

    PO Box 208051, 333 Cedar Street, TMP 3

    New Haven, CT 06520-8051

    United States

Yale Medicine

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Research Summary

My scholarly contributions and research have been in pain with an emphasis on ambulatory pain control.My clinical investigation and clinical observations in pain control at the ambulatory surgery center has helped guide my educational activities in the field of ambulatory pain and, have helped in advancing the reputation of our department as a center of clinical research and scholarly excellence. My clinical investigations have been conducted in the Ambulatory Surgery Center of Yale New Haven Hospital with scholarship related to this clinical research most often published with house staff,

Extensive Research Description

My research in ambulatory pain control can be divided into several subtopics as detailed below

1) Perioperative pain management in ambulatory surgery

My interest in the area of perioperative pain management in ambulatory surgery has led to clinical investigations, extensive literature searches and scholarship in this area. My pain research studies and scholarly contributions in the control of perioperative pain at the ambulatory surgery center aims at increasing awareness and improving pain control in ambulatory care centers worldwide. These works include:

. 2) Alternative therapies for perioperative treatment of pain in the ambulatory setting. Managing pain control in the presence of alternative therapies is a challenge and research in this area at the ambulatory surgery center in which I participate is ongoing

3) Analgesics for pain control in ambulatory surgery I have a long-term interest in the analgesics taken by patients for the control of pain who then present for ambulatory surgery. My scholarly writings and research efforts have been directed at increasing awareness of the use of these drugs, and suggesting ideal ways to manage pain in these patients safely within the ambulatory setting.

4) Regional blocks and Interventional pain management in ambulatory surgery

Regional blocks are one of the multimodal treatments used to control pain in the ambulatory setting. Patients with chronic pain presenting for ambulatory surgery sometimes have implanted pain control devices and perioperative management of these patients are a great challenge. My research studies and scholarship in these areas has always focused on safety first.

. 5) Research and Scholarship on perioperative pain control education for ambulatory surgery.

I have been involved in evaluating research surveys of patients undergoing ambulatory surgery at Yale, which found that physicians who are not trained in pain management treated 90 percent of patients for their painful conditions. This highlighted the need to educate all physicians and health care professionals in the field of pain management. The primary care provider helps to best achieve optimum pain management of pain patients in the ambulatory surgery center through preoperative preparation of these patients and postoperative care. This collaboration is best achieved by starting pain education early in one’s career, as in at the medical school level. Seeing this has led me to produce scholarly works in order to educate health care professionals so they can provide optimum pain management worldwide with special emphasis on pain management at the ambulatory surgery center.

6)Perioperative management of the opioid dependent, drug tolerant, drug dependent and substance abuse patient in ambulatory surgery

With the rapidly increasing numbers of patients with opioid dependence, substance abuse and addiction presenting for ambulatory surgery, I have an ongoing interest on how to improve the care of these patients in the ambulatory surgery center. As a result of clinical observations, intense literature searches and studies on the pain management of patients with drug tolerance, drug dependence and addiction, at the ambulatory surgery center, I and physicians from several national universities and international universities have researched and written several manuscripts on the topic and have also been an edited a textbook on the management of patients with Substance Abuse in the Outpatient Setting .

7) Pain management for specific surgeries performed in ambulatory surgery centers

I have focused my clinical research studies and scholarly works on pain control for specific surgeries in collaboration with several physicians who commonly performed these procedures in the ambulatory surgery center. My collaborative research efforts at the Yale Ambulatory Surgery Center have been performed in conjunction with Yale physicians in the Departments of Surgery Podiatry , Gynecology, Ophthalmology and Plastic Surgery.

8) Research in Caring for the palliative care patients in ambulatory surgery

. To further understand the problem of pain control in palliative care patients undergoing surgery in the ambulatory setting, as well to increase awareness of the challenge of caring for these patients.I have conducted research in collaboration with other physicians on the pain management of terminally ill patients and palliative care patients having surgery,

Coauthors

Research Interests

Health Care

Selected Publications

  • ERAS Protocol Options for Perioperative Pain Management of Substance Use Disorder in the Ambulatory Surgical SettingZwolinski N, Patel K, Vadivelu N, Kodumudi G, Kaye A. ERAS Protocol Options for Perioperative Pain Management of Substance Use Disorder in the Ambulatory Surgical Setting. Current Pain And Headache Reports 2023, 27: 65-79. PMID: 37079258, PMCID: PMC10116112, DOI: 10.1007/s11916-023-01108-3.
  • KetamineShergill S, Vadivelu N. Ketamine. 2023, 195-205. DOI: 10.1007/978-3-031-21291-8_13.
  • AnticonvulsantsPopovitz E, Li J, Vadivelu N. Anticonvulsants. 2023, 139-146. DOI: 10.1007/978-3-031-21291-8_9.
  • Evolving Therapeutic Roles of Nasogastric Tubes: Current Concepts in Clinical PracticeVadivelu N, Kodumudi G, Leffert L, Pierson D, Rein L, Silverman M, Cornett E, Kaye A. Evolving Therapeutic Roles of Nasogastric Tubes: Current Concepts in Clinical Practice. Advances In Therapy 2023, 40: 828-843. PMID: 36637690, PMCID: PMC9838367, DOI: 10.1007/s12325-022-02406-9.
  • Weaning Protocols After Ambulatory SurgeryAggarwal N, Zafar J, Kodumudi G, Vadivelu N, Laurans M, Rajput K. Weaning Protocols After Ambulatory Surgery. 2021, 369-377. DOI: 10.1007/978-3-030-55262-6_28.
  • Special Considerations – Indwelling Spinal Cord Stimulators and Intrathecal PumpsBeals C, Chow R, Vadivelu N, Rajput K. Special Considerations – Indwelling Spinal Cord Stimulators and Intrathecal Pumps. 2021, 335-343. DOI: 10.1007/978-3-030-55262-6_25.
  • Pain Management in Former Addicts on Medication-Assisted Treatment (MAT) ProgramRajput K, Kodumudi G, Vadivelu N. Pain Management in Former Addicts on Medication-Assisted Treatment (MAT) Program. 2021, 309-325. DOI: 10.1007/978-3-030-55262-6_23.
  • Recovery Room Protocols for Nursing in Ambulatory Surgery Centers (ASCs) and Hospital Outpatient Departments (HOPDs)Zafar J, Vadivelu N, Rajput K, Fontanez P. Recovery Room Protocols for Nursing in Ambulatory Surgery Centers (ASCs) and Hospital Outpatient Departments (HOPDs). 2021, 355-367. DOI: 10.1007/978-3-030-55262-6_27.
  • Current US Policy for Opioid PrescribingShah A, Haddad D, Vadivelu N, Rajput K. Current US Policy for Opioid Prescribing. 2021, 29-41. DOI: 10.1007/978-3-030-55262-6_3.
  • Ultrasound Guided Brachial Plexus BlockLi J, Sharma A, Credaroli E, Vadivelu N, Liu H. Ultrasound Guided Brachial Plexus Block. 2021, 121-128. DOI: 10.1007/978-3-030-46839-2_13.
  • Common Congenital Syndromes and Disease States Impacting Regional Anesthesiology TechniquesThomas D, Missih O, Zhu R, Suchy T, Vadivelu N. Common Congenital Syndromes and Disease States Impacting Regional Anesthesiology Techniques. 2020, 111-122. DOI: 10.1007/978-3-030-55660-0_6.
  • Neuraxial Blockade: Epidural AnesthesiaKunnumpurath S, Ramessur S, Fendius A, Vadivelu N, Perinpanayagam J. Neuraxial Blockade: Epidural Anesthesia. 2018, 233-263. DOI: 10.1007/978-3-319-74838-2_12.
  • Role of Alternative Therapies for Chronic Pain SyndromesThomas DA, Maslin B, Legler A, Springer E, Asgerally A, Vadivelu N. Role of Alternative Therapies for Chronic Pain Syndromes. Current Pain And Headache Reports 2016, 20: 29. PMID: 27038968, DOI: 10.1007/s11916-016-0562-z.
  • Facial Pain Update: Advances in Neurostimulation for the Treatment of Facial PainManiam R, Kaye AD, Vadivelu N, Urman RD. Facial Pain Update: Advances in Neurostimulation for the Treatment of Facial Pain. Current Pain And Headache Reports 2016, 20: 24. PMID: 26896948, DOI: 10.1007/s11916-016-0553-0.
  • Vadivelu N, Lumermann L, Zhu R, Kodumudi G, Elhassan AO, Kaye AD. Pain Control in the Presence of Drug Addiction. Curr Pain Headache Rep. 2016 May;20(5):35 Vadivelu N, Lumermann L, Zhu R, Kodumudi G, Elhassan AO, Kaye AD. Pain Control in the Presence of Drug Addiction. Curr Pain Headache Rep. 2016 May;20(5):35
  • Efficacy and Safety of Nonopioid Analgesics in Perioperative Pain Control.Thomas DA, West M, Legler A, Maslin B, Kim RK, Vadivelu N. Efficacy and Safety of Nonopioid Analgesics in Perioperative Pain Control. Current Drug Safety 2016, 11: 196-205. PMID: 27113953, DOI: 10.2174/1574886311666160426130444.
  • Perioperative Safety of Warfarin Therapy and Reversal.Maslin B, Springer E, Zhu R, Kodumudi V, Vadivelu N. Perioperative Safety of Warfarin Therapy and Reversal. Current Drug Safety 2016, 11: 149-55. PMID: 26674352, DOI: 10.2174/1574886311666151217121553.
  • Effects of Anesthetic Management on Early Postoperative Recovery, Hemodynamics and Pain After Supratentorial CraniotomyAyrian E, Kaye AD, Varner CL, Guerra C, Vadivelu N, Urman RD, Zelman V, Lumb PD, Rosa G, Bilotta F. Effects of Anesthetic Management on Early Postoperative Recovery, Hemodynamics and Pain After Supratentorial Craniotomy. Journal Of Clinical Medicine Research 2015, 7: 731-741. PMID: 26345202, PMCID: PMC4554211, DOI: 10.14740/jocmr2256w.
  • Vadivelu N, Gowda AM, Urman RD, Jolly S, Kodumudi V, Monisa M, Taylor R, Jr, Pergolizzi JV. Ketorolac Tromethamine – Routes and clinical implications. Pain Pract. 2015 Feb;15(2):175-93.Vadivelu N, Gowda AM, Urman RD, Jolly S, Kodumudi V, Monisa M, Taylor R, Jr, Pergolizzi JV. Ketorolac Tromethamine – Routes and clinical implications. Pain Pract. 2015 Feb;15(2):175-93.
  • Hingula L, Maslin B, Rao S, Wood S, Roberts K, Kodumudi G, Schermer E, Vadivelu N. Perioperative pain control in gastroenterintestinal surgery. Middle East J Anaesthesiol. 2015 Jun;23(2):137-4 Epub 2015 Feb 5. ReviewHingula L, Maslin B, Rao S, Wood S, Roberts K, Kodumudi G, Schermer E, Vadivelu N. Perioperative pain control in gastroenterintestinal surgery. Middle East J Anaesthesiol. 2015 Jun;23(2):137-4 Epub 2015 Feb 5. Review
  • Tapentadol extended release in the management of peripheral diabetic neuropathic painVadivelu N, Kai A, Maslin B, Kodumudi G, Legler A, Berger JM. Tapentadol extended release in the management of peripheral diabetic neuropathic pain. Therapeutics And Clinical Risk Management 2015, Volume 11: 95-105. PMID: 25609974, PMCID: PMC4298300, DOI: 10.2147/tcrm.s32193.
  • TobaccoBasu D, Mitra S, Vadivelu N. Tobacco. 2015, 89-107. DOI: 10.1007/978-1-4939-1951-2_9.
  • Postoperative Pain Control in Drug Abusing PatientsGevirtz C, Vadivelu N, Kaye A. Postoperative Pain Control in Drug Abusing Patients. 2015, 379-387. DOI: 10.1007/978-1-4939-1951-2_30.
  • Cocaine AbuseKahn E, Mikhael H, Vadivelu N. Cocaine Abuse. 2015, 143-154. DOI: 10.1007/978-1-4939-1951-2_12.
  • Transvaginal cholecystectomy learning curveWood SG, Dai F, Dabu-Bondoc S, Mikhael H, Vadivelu N, Duffy A, Roberts KE. Transvaginal cholecystectomy learning curve. Surgical Endoscopy 2014, 29: 1837-1841. PMID: 25294548, DOI: 10.1007/s00464-014-3873-3.
  • Intrathecal drug delivery for chronic pain management-scope, limitations and futureCzernicki M, Sinovich G, Mihaylov I, Nejad B, Kunnumpurath S, Kodumudi G, Vadivelu N. Intrathecal drug delivery for chronic pain management-scope, limitations and future. Journal Of Clinical Monitoring And Computing 2014, 29: 241-249. PMID: 25173564, DOI: 10.1007/s10877-014-9607-1.
  • Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and Postanesthesia Care Unit Length of StayDabu-Bondoc S, Vadivelu N, Shimono C, English A, Kosarussavadi B, Dai F, Shelley K, Feinleib J. Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and Postanesthesia Care Unit Length of Stay. Survey Of Anesthesiology 2014, 58: 57-58. DOI: 10.1097/01.sa.0000443063.72052.e7.
  • Availability and utilization of opioids for pain management: global issues.Manjiani D, Paul DB, Kunnumpurath S, Kaye AD, Vadivelu N. Availability and utilization of opioids for pain management: global issues. Ochsner Journal 2014, 14: 208-15. PMID: 24940131, PMCID: PMC4052588.
  • Chromosomal Aberrations and Exon 1 Mutation in the AKR1B1 Gene in Patients with Diabetic Neuropathy.Saraswathy R, Anand S, Kunnumpurath SK, Kurian RJ, Kaye AD, Vadivelu N. Chromosomal Aberrations and Exon 1 Mutation in the AKR1B1 Gene in Patients with Diabetic Neuropathy. Ochsner Journal 2014, 14: 339-42. PMID: 25249799, PMCID: PMC4171791.
  • Practical guide to the management of acute and chronic pain in the presence of drug tolerance for the healthcare practitioner.Vadivelu N, Singh-Gill H, Kodumudi G, Kaye AJ, Urman RD, Kaye AD. Practical guide to the management of acute and chronic pain in the presence of drug tolerance for the healthcare practitioner. Ochsner Journal 2014, 14: 426-33. PMID: 25249810, PMCID: PMC4171802.
  • Perioperative dilemma: challenges of the management of a patient on mega doses of morphine and methadone.Kaye AD, Alian AA, Vadivelu N, Chung KS. Perioperative dilemma: challenges of the management of a patient on mega doses of morphine and methadone. Journal Of Opioid Management 2014, 10: 69-72. PMID: 24604572, DOI: 10.5055/jom.2014.0194.
  • Nociceptive Chemical Mediators in Oral InflammationVadivelu N, Gowda A, Thorp S, Kai A, Vadivelu A, Dabu-Bondoc S. Nociceptive Chemical Mediators in Oral Inflammation. 2013, 25-33. DOI: 10.1007/978-3-319-01875-1_4.
  • The Neurobiology of Orofacial PainVadivelu N, Huang Y, Mancini P, Gruenbaum S, Vadivelu A, Dabu-Bondoc S. The Neurobiology of Orofacial Pain. 2013, 1-8. DOI: 10.1007/978-3-319-01875-1_1.
  • Comparison of immediate postoperative pain after transvaginal versus traditional laparoscopic cholecystectomyWood SG, Dabu-Bondoc S, Dai F, Mikhael H, Vadivelu N, Roberts KE. Comparison of immediate postoperative pain after transvaginal versus traditional laparoscopic cholecystectomy. Surgical Endoscopy 2013, 28: 1141-1145. PMID: 24232050, DOI: 10.1007/s00464-013-3294-8.
  • Clinical applications of oxymorphone.Vadivelu N, Maria M, Jolly S, Rosenbloom J, Prasad A, Kaye AD. Clinical applications of oxymorphone. Journal Of Opioid Management 2013, 9: 439-52. PMID: 24481932, DOI: 10.5055/jom.2013.0186.
  • Patient considerations in the use of tapentadol for moderate to severe painVadivelu N, Huang Y, Mirante B, Jacoby M, Braveman FR, Hines RL, Sinatra R. Patient considerations in the use of tapentadol for moderate to severe pain. Drug Healthcare And Patient Safety 2013, Volume 5: 151-159. PMID: 23861601, PMCID: PMC3704302, DOI: 10.2147/dhps.s28829.
  • Common misconceptions about opioid use for pain management at the end of life.Berger JM, Vadivelu N. Common misconceptions about opioid use for pain management at the end of life. The AMA Journal Of Ethic 2013, 15: 403-9. PMID: 23680560, DOI: 10.1001/virtualmentor.2013.15.5.ecas1-1305.
  • Berger JM, Vadivelu N. Ethics Case: Common misconceptions about opioid use for pain management at the end of life. Virtual Mentor 2013; 15(5):403-409. Berger JM, Vadivelu N. Ethics Case: Common misconceptions about opioid use for pain management at the end of life. Virtual Mentor 2013; 15(5):403-409.
  • Vadivelu N, Mitra S, Hines RL. Undergraduate medical education on pain managementacross the globe. Virtual Mentor 2013; May 1; 15(5):421-427. Vadivelu N, Mitra S, Hines RL. Undergraduate medical education on pain managementacross the globe. Virtual Mentor 2013; May 1; 15(5):421-427.
  • Anesthetic considerations in robotic-assisted gynecologic surgery.Kaye AD, Vadivelu N, Ahuja N, Mitra S, Silasi D, Urman RD. Anesthetic considerations in robotic-assisted gynecologic surgery. Ochsner Journal 2013, 13: 517-24. PMID: 24358000, PMCID: PMC3865830.
  • Diabetic neuropathyVadivelu N. Diabetic neuropathy. International Journal Of Nutrition Pharmacology Neurological Diseases 2013, 3: 332-334. DOI: 10.4103/2231-0738.119839.
  • Postoperative apnea, respiratory strategies, and pathogenesis mechanisms: a reviewKaye AD, Hollon MM, Vadivelu N, Kodumudi G, Kaye RJ, Bueno FR, Baluch AR. Postoperative apnea, respiratory strategies, and pathogenesis mechanisms: a review. Journal Of Anesthesia 2012, 27: 423-432. PMID: 23179739, DOI: 10.1007/s00540-012-1517-0.
  • Guidance with Complex Treatment ChoicesMitra S, Vadivelu N. Guidance with Complex Treatment Choices. 2012, 89-105. DOI: 10.1007/978-1-4614-5164-8_6.
  • Multidisciplinary Approach and Coordination of CareMitra S, Vadivelu N. Multidisciplinary Approach and Coordination of Care. 2012, 7-21. DOI: 10.1007/978-1-4614-5164-8_2.
  • Prevention and management of complications of regional orbital anesthesia.Vadivelu N, Huang Y, Kaye AD, Kodumudi V, Kai A, Adelman RA. Prevention and management of complications of regional orbital anesthesia. Middle East Journal Of Anaesthesiology 2012, 21: 775-84. PMID: 23634558.
  • Peripheral Opioid Agonists for AnalgesiaVadivelu N, Mitra S, Hines R. Peripheral Opioid Agonists for Analgesia. Survey Of Anesthesiology 2012, 56: 200. DOI: 10.1097/01.sa.0000415552.38044.37.
  • Acute Pain in Undergraduate Medical Education: An Unfinished Chapter!Vadivelu N, Mitra S, Hines R, Elia M, Rosenquist RW. Acute Pain in Undergraduate Medical Education: An Unfinished Chapter! Pain Practice 2012, 12: 663-671. PMID: 22712557, DOI: 10.1111/j.1533-2500.2012.00580.x.
  • Su1501 Transvaginal Notes Cholecystectomy: Retrospective Analysis of Immediate Post-Operative PainWood S, Vadivelu N, Hosni M, Dabu-Bondoc S, Dai F, Panait L, Bell R, Duffy A, Longo W, Roberts K. Su1501 Transvaginal Notes Cholecystectomy: Retrospective Analysis of Immediate Post-Operative Pain. Gastroenterology 2012, 142: s-1050. DOI: 10.1016/s0016-5085(12)64070-0.
  • Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and Postanesthesia Care Unit Length of StayDabu-Bondoc S, Vadivelu N, Shimono C, English A, Kosarussavadi B, Dai F, Shelley K, Feinleib J. Intravenous Dextrose Administration Reduces Postoperative Antiemetic Rescue Treatment Requirements and Postanesthesia Care Unit Length of Stay. Anesthesia & Analgesia 2012, 117: 591-596. PMID: 22253268, DOI: 10.1213/ane.0b013e3182458f9e.
  • Neuraxial Blockade: Epidural AnesthesiaKunnumpurath S, Ramessur S, Fendius A, Vadivelu N. Neuraxial Blockade: Epidural Anesthesia. 2011, 293-338. DOI: 10.1007/978-1-4614-1013-3_12.
  • Pain Relief in Laparoscopic Cholecystectomy—A Review of the Current OptionsMitra S, Khandelwal P, Roberts K, Kumar S, Vadivelu N. Pain Relief in Laparoscopic Cholecystectomy—A Review of the Current Options. Pain Practice 2011, 12: 485-496. PMID: 22008277, DOI: 10.1111/j.1533-2500.2011.00513.x.
  • Tapentadol extended-release for treatment of chronic pain: a reviewVadivelu N, Timchenko A, Huang Y, Sinatra R. Tapentadol extended-release for treatment of chronic pain: a review. Journal Of Pain Research 2011, Volume 4: 211-218. PMID: 21887118, PMCID: PMC3160834, DOI: 10.2147/jpr.s14842.
  • Safety of spinal anesthesia in a patient with achondroplasia for cesarean section.Mikhael H, Vadivelu N, Braveman F. Safety of spinal anesthesia in a patient with achondroplasia for cesarean section. Current Drug Safety 2011, 6: 130-1. PMID: 21375478, DOI: 10.2174/157488611795684668.
  • Peripheral opioid receptor agonists for analgesia: a comprehensive review.Vadivelu N, Mitra S, Hines RL. Peripheral opioid receptor agonists for analgesia: a comprehensive review. Journal Of Opioid Management 2011, 7: 55-68. PMID: 21434585, DOI: 10.5055/jom.2011.0049.
  • Managing Pain in the Addicted PatientDabu-Bondoc S, Zhang R, Vadivelu N. Managing Pain in the Addicted Patient. 2010, 671-697. DOI: 10.1007/978-0-387-87579-8_31.
  • Fibromyalgia, Arthritic, and Myofascial PainVadivelu N, Urman R. Fibromyalgia, Arthritic, and Myofascial Pain. 2010, 557-566. DOI: 10.1007/978-0-387-87579-8_25.
  • Buprenorphine in Postoperative Pain ManagementVadivelu N, Anwar M. Buprenorphine in Postoperative Pain Management. Anesthesiology Clinics 2010, 28: 601-609. PMID: 21074740, DOI: 10.1016/j.anclin.2010.08.015.
  • Buprenorphine: intravenous neuraxial and transdermal applicationsVadivelu N. Buprenorphine: intravenous neuraxial and transdermal applications. 2010, 157-160. DOI: 10.1017/cbo9780511841378.035.
  • Safety of Local Anesthesia Combined with Monitored Intravenous Sedation for American Society of Anesthesiologists 3 and 4 Patients Undergoing Lower Limb–preservation ProceduresVadivelu N, Gesquire M, Mitra S, Shelley K, Kodumudi G, Xia Y, Blume P. Safety of Local Anesthesia Combined with Monitored Intravenous Sedation for American Society of Anesthesiologists 3 and 4 Patients Undergoing Lower Limb–preservation Procedures. The Journal Of Foot & Ankle Surgery 2010, 49: 152-154. PMID: 20137984, DOI: 10.1053/j.jfas.2009.09.006.
  • Hemispheric Synchronized Sounds and Perioperative Analgesic RequirementsDabu-Bondoc S, Vadivelu N, Benson J, Perret D, Kain ZN. Hemispheric Synchronized Sounds and Perioperative Analgesic Requirements. Anesthesia & Analgesia 2009, 110: 208-210. PMID: 19861358, DOI: 10.1213/ane.0b013e3181bea424.
  • LOW‐DOSE KETAMINE AS AN ADJUNCT TO ROUTINE PAIN PRACTICE: ARE WE READY YET?Souzdalnitski D, Vadivelu N, Chung KS. LOW‐DOSE KETAMINE AS AN ADJUNCT TO ROUTINE PAIN PRACTICE: ARE WE READY YET? Pain Practice 2009, 9: 405-406. PMID: 19740273, DOI: 10.1111/j.1533-2500.2009.00302.x.
  • Pain Quality Assessment Scale: Practical Implications of Factor AnalysisSouzdalnitski D, Bolinske T, Vadivelu N. Pain Quality Assessment Scale: Practical Implications of Factor Analysis. The Clinical Journal Of Pain 2009, 25: 453. PMID: 19454882, DOI: 10.1097/ajp.0b013e318193cf50.
  • Pain Pathways and Acute Pain ProcessingMcQuay H, Vadivelu N, Whitney C, Sinatra R. Pain Pathways and Acute Pain Processing. 2009, 3-20. DOI: 10.1017/cbo9780511576706.003.
  • The Urgent Need for Pain Management TrainingVadivelu N, Kombo N, Hines RL. The Urgent Need for Pain Management Training. Academic Medicine 2009, 84: 408. PMID: 19318764, DOI: 10.1097/acm.0b013e31819a8358.
  • Nicotine in postoperative pain managementSouzdalnitski D, Dabu-Bondoc S, Vadivelu N, Chung K. Nicotine in postoperative pain management. Journal Of Pain 2009, 10: s34. DOI: 10.1016/j.jpain.2009.01.146.
  • Management of chronic pain in the elderly: focus on transdermal buprenorphineVadivelu N, Hines RL. Management of chronic pain in the elderly: focus on transdermal buprenorphine. Clinical Interventions In Aging 2008, Volume 3: 421-430. PMID: 18982913, PMCID: PMC2682375, DOI: 10.2147/cia.s1880.
  • Article Commentary: Pain after Mastectomy and Breast ReconstructionVadivelu N, Schreck M, Lopez J, Kodumudi G, Narayan D. Article Commentary: Pain after Mastectomy and Breast Reconstruction. The American Surgeon 2008, 74: 285-296. PMID: 18453290, DOI: 10.1177/000313480807400402.
  • Post Dural Puncture Headache and HypertensionVadivelu N, Whitney C, Kodumudi G, Gudin M. Post Dural Puncture Headache and Hypertension. Current Hypertension Reviews 2008, 4: 73-77. DOI: 10.2174/157340208783497200.
  • CHAPTER 20 CancerVadivelu N. CHAPTER 20 Cancer. 2008, 501-520. DOI: 10.1016/b978-1-4160-3998-3.10020-x.
  • Can the Shikani Optical Stylet facilitate intubation in simulated difficult direct laryngoscopy?Young CF, Vadivelu N. Can the Shikani Optical Stylet facilitate intubation in simulated difficult direct laryngoscopy? Connecticut Medicine 2007, 71: 407-8. PMID: 17879863.
  • Does the use of a laryngoscope facilitate orotracheal intubation with a Shikani Optical Stylet?Young C, Vadivelu N. Does the use of a laryngoscope facilitate orotracheal intubation with a Shikani Optical Stylet? British Journal Of Anaesthesia 2007, 99: 302-303. PMID: 17616572, DOI: 10.1093/bja/aem196.
  • Buprenorphine: a unique opioid with broad clinical applications.Vadivelu N, Hines RL. Buprenorphine: a unique opioid with broad clinical applications. Journal Of Opioid Management 2007, 3: 49-58. PMID: 17367094, DOI: 10.5055/jom.2007.0038.
  • Perioperative pain management in a highly opioid dependent patientVadivelu N, Marshall K, Feinleib J, Sinatra R. Perioperative pain management in a highly opioid dependent patient. British Journal Of Anaesthesia 2006, 97 DOI: 10.1093/bja/el_1403.
  • Vadivelu N, Freiberg C, Sinatra RS Epidural blood patch in patient on high dose Enoxaparin. Anesthesia and Analgesia September 2006; 103(3):88-9. Vadivelu N, Freiberg C, Sinatra RS Epidural blood patch in patient on high dose Enoxaparin. Anesthesia and Analgesia September 2006; 103(3):88-9.
  • Prolonged post-dural puncture headache in a patient with a renal transplant.Vadivelu N, Mikhael H, Gordon M, Vindhya M, Holt N. Prolonged post-dural puncture headache in a patient with a renal transplant. Connecticut Medicine 2006, 70: 13-4. PMID: 16479870.
  • Chapter 10 Complication and Risk Management in Obstetrics and Gynecologic AnesthesiaVadivelu N. Chapter 10 Complication and Risk Management in Obstetrics and Gynecologic Anesthesia. 2006, 118-125. DOI: 10.1016/b978-0-323-02420-4.50014-9.
  • Recent advances in elucidating pain mechanismsVadivelu N, Sinatra R. Recent advances in elucidating pain mechanisms. Current Opinion In Anaesthesiology 2005, 18: 540. PMID: 16534290, DOI: 10.1097/01.aco.0000183109.27297.75.
  • Successful cesarean section performed with inadvertent subdural anesthesia.Vadivelu N, Yusufali T, Braveman F. Successful cesarean section performed with inadvertent subdural anesthesia. Connecticut Medicine 2005, 69: 71-2. PMID: 15779602.
  • Buprenorphine pharmacology and clinical applicationsVadivelu N, Hines R. Buprenorphine pharmacology and clinical applications. Journal Of Critical Care 2004, 23: 281-290. DOI: 10.1053/j.sane.2003.12.012.
  • Chronic Testicular Pain in a Patient with DiverticulitisVadivelu N, Tundis D. Chronic Testicular Pain in a Patient with Diverticulitis. Journal Of Pain And Symptom Management 2003, 25: 404-405. PMID: 12727036, DOI: 10.1016/s0885-3924(03)00100-3.
  • Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life careBerger J, Ryan A, Vadivelu N, Merriam P, Rever L, Harrison P. Ketamine-fentanyl-midazolam infusion for the control of symptoms in terminal life care. American Journal Of Hospice And Palliative Medicine® 2000, 17: 127-134. PMID: 11406957, DOI: 10.1177/104990910001700213.
  • Vadivelu N, Berger JM: Neuropathic Pain after anti HIV gene therapy successfully treated with Gabapentin. J of Pain and Symptom Management 1999; 17:3-155. Vadivelu N, Berger JM: Neuropathic Pain after anti HIV gene therapy successfully treated with Gabapentin. J of Pain and Symptom Management 1999; 17:3-155.
  • Thyroid stimulating hormone receptor antibody in thyroid diseases.Vadivelu N, Stephen DC, Kanagasabapathy AS, Seshadri MS. Thyroid stimulating hormone receptor antibody in thyroid diseases. The Indian Journal Of Medical Research 1990, 92: 220-3. PMID: 1977696.
  • Vadivelu N, Seshadri MS, Kanakasabapathy AS: Dextran coated charcoal is not suitable for suitable for phase separation of free TSH from receptor bound TSH in TSH binding inhibitory immunoglobulin assays. Indian Journal of Clinical Biochemistry 1988; 3:27-31. Vadivelu N, Seshadri MS, Kanakasabapathy AS: Dextran coated charcoal is not suitable for suitable for phase separation of free TSH from receptor bound TSH in TSH binding inhibitory immunoglobulin assays. Indian Journal of Clinical Biochemistry 1988; 3:27-31.
  • HDL: total cholesterol & HDL2:HDL3 cholesterol ratios in liver diseases.Vadivelu N, Ramakrishnan S. HDL: total cholesterol & HDL2:HDL3 cholesterol ratios in liver diseases. The Indian Journal Of Medical Research 1986, 83: 46-52. PMID: 3699868.
  • Vadivelu N, Harkness P, Richman S, Shelley KH: Special anesthetic concerns in mentally challenged patients undergoing gynecological procedures in an outpatient setting. Connecticut Medicine 2004; 68:359-362. Vadivelu N, Harkness P, Richman S, Shelley KH: Special anesthetic concerns in mentally challenged patients undergoing gynecological procedures in an outpatient setting. Connecticut Medicine 2004; 68:359-362.
  • Young CF, Vadivelu N. Does the use of a laryngoscope facilitate orotracheal intubation with a Shikani Optical Stylet? Br J Anaesth. 2007; 99(2):302-3. Young CF, Vadivelu N. Does the use of a laryngoscope facilitate orotracheal intubation with a Shikani Optical Stylet? Br J Anaesth. 2007; 99(2):302-3.
  • Vadivelu N, Whitney C, Kodumudi G, Gudin M. Post dural puncture headache and hypertension. Current Hypertension Reviews 2008; 4(1):73-77. Vadivelu N, Whitney C, Kodumudi G, Gudin M. Post dural puncture headache and hypertension. Current Hypertension Reviews 2008; 4(1):73-77.
  • Vadivelu N, Bustos A, Sinatra, RS Pain Management for Orthopedic Procedures. Business Briefing: US Orthopedics Review, January 2006; 57-59. Vadivelu N, Bustos A, Sinatra, RS Pain Management for Orthopedic Procedures. Business Briefing: US Orthopedics Review, January 2006; 57-59.
  • Fields AM, Vadivelu N. Sugammadex: A novel neuromuscular blocker binding agent. Curr Opin Anaesthesiol. 2007; 20(4):307-10. Fields AM, Vadivelu N. Sugammadex: A novel neuromuscular blocker binding agent. Curr Opin Anaesthesiol. 2007; 20(4):307-10.
  • Kunnumpurath S, Srinivasagopalan R, Vadivelu N. Spinal cord stimulation: Principles of past, present and future practice: A review. J Clin Monit Comput 2009; 23(5):333-9. Kunnumpurath S, Srinivasagopalan R, Vadivelu N. Spinal cord stimulation: Principles of past, present and future practice: A review. J Clin Monit Comput 2009; 23(5):333-9.
  • Vadivelu N, Mitra S, Narayan, N. Recent advances in postoperative pain management. Yale Journal of Biology and Medicine. Yale J Biol Med 2010; 83(1):11-25. Vadivelu N, Mitra S, Narayan, N. Recent advances in postoperative pain management. Yale Journal of Biology and Medicine. Yale J Biol Med 2010; 83(1):11-25.
  • Vadivelu N, Chen IL, Kodumudi V, Ortigosa E, Gudin MT. The implications of urine drug testing in pain management. Curr Drug Saf. 2010; 5(3):267-270. Vadivelu N, Chen IL, Kodumudi V, Ortigosa E, Gudin MT. The implications of urine drug testing in pain management. Curr Drug Saf. 2010; 5(3):267-270.
  • Kaye AD, Patel N, Bueno FR, Hymel, Vadivelu N, Kodumudi G, Urman RD. Effect of opiates, anesthetic techniques, and other perioperative factors on surgical cancer patients,Ochsner Journal 2014 Summer; 14(2):216-228. Kaye AD, Patel N, Bueno FR, Hymel, Vadivelu N, Kodumudi G, Urman RD. Effect of opiates, anesthetic techniques, and other perioperative factors on surgical cancer patients,Ochsner Journal 2014 Summer; 14(2):216-228.
  • Vadivelu N, Mitra S, Kaye AD, Urman RD. Perioperative analgesia and challenges in the drug addicted and drug dependent patient. Bailliere’s Best Practice & Research Clinical Anaesthesiology 2014; 28(1); 91-102. Vadivelu N, Mitra S, Kaye AD, Urman RD. Perioperative analgesia and challenges in the drug addicted and drug dependent patient. Bailliere’s Best Practice & Research Clinical Anaesthesiology 2014; 28(1); 91-102.
  • Vadivelu N, Mitra S, Schermer E, Kodumudi V, Kaye AD, Urman RD. Preventive analgesia for postoperative pain control: a broader concept. Local and Regional Anesthesia 2014; 29(7):17-22. Vadivelu N, Mitra S, Schermer E, Kodumudi V, Kaye AD, Urman RD. Preventive analgesia for postoperative pain control: a broader concept. Local and Regional Anesthesia 2014; 29(7):17-22.
  • Gritsenka K, Khelemsky Y, Kay A, Vadivelu N, Urman R. Multimodal therapy in perioperative analgesia. Best Pract Res Clin Anaesthesiol 2014 Mar; 28(1):59-79. Gritsenka K, Khelemsky Y, Kay A, Vadivelu N, Urman R. Multimodal therapy in perioperative analgesia. Best Pract Res Clin Anaesthesiol 2014 Mar; 28(1):59-79.
  • Vadivelu N, Kai MA, Maslin B, Kodumudi V, Antony S, Blume P. Role of regional anesthesia in foot and ankle surgery. Foot and Ankle Specialist. Foot Ankle Spec. 2015 Jun;8(3):212-219. Vadivelu N, Kai MA, Maslin B, Kodumudi V, Antony S, Blume P. Role of regional anesthesia in foot and ankle surgery. Foot and Ankle Specialist. Foot Ankle Spec. 2015 Jun;8(3):212-219.
  • Vadivelu N, Kai AM, Tran D, Kodumudi G, Legler A, Ayrian E. Options for perioperative pain management in neurosurgery.J Pain Res. 2016 Feb 10;9:37-47 Vadivelu N, Kai AM, Tran D, Kodumudi G, Legler A, Ayrian E. Options for perioperative pain management in neurosurgery.J Pain Res. 2016 Feb 10;9:37-47
  • Vadivelu N, Lumermann L, Zhu R, Kodumudi G, Elhassan AO, Kaye AD. Pain Control in the Presence of Drug Addiction. Curr Pain Headache Rep. 2016 May;20(5):35 Vadivelu N, Lumermann L, Zhu R, Kodumudi G, Elhassan AO, Kaye AD. Pain Control in the Presence of Drug Addiction. Curr Pain Headache Rep. 2016 May;20(5):35
  • Chung KS, Carson S, Glassman D, Vadivelu N: Successful treatment of Hydromorphone induced Neurotoxicity and Hyperalgesia. Connecticut Medicine 2004; 68:247-249. Chung KS, Carson S, Glassman D, Vadivelu N: Successful treatment of Hydromorphone induced Neurotoxicity and Hyperalgesia. Connecticut Medicine 2004; 68:247-249.
  • Kaye AD, Chung KS, Vadivelu N, Cantemir C, Urman RD, Manchikanl L. Opioid induced hyperalgesia altered with propofol infusion. Pain Physician 2014; 17(2):E225-E228. Kaye AD, Chung KS, Vadivelu N, Cantemir C, Urman RD, Manchikanl L. Opioid induced hyperalgesia altered with propofol infusion. Pain Physician 2014; 17(2):E225-E228.
  • Vadivelu N, Complications and Risk Management in: Obstetrics and Gynecologic Anesthesia. In: Braveman, FR: (Editor) Obstretical and Gynecologic Anesthesia:(Requisites in Anesthesiology). Elsevier Science, NY, NY, 2006, 118-125 Vadivelu N, Complications and Risk Management in: Obstetrics and Gynecologic Anesthesia. In: Braveman, FR: (Editor) Obstretical and Gynecologic Anesthesia:(Requisites in Anesthesiology). Elsevier Science, NY, NY, 2006, 118-125
  • Vadivelu N, Cancer In: Hines RL, Marschall KE (eds) Anesthesia and Co-ExistingDisease, 5th Edition, 2007, 501-520Vadivelu N, Cancer In: Hines RL, Marschall KE (eds) Anesthesia and Co-ExistingDisease, 5th Edition, 2007, 501-520
  • Vadivelu N, Whitney C, Acute Pain Management in: Urman RD and Ehrenfield J. (eds) Pocket Anesthesia. Lippincott Williams & Wilkins, Philadelphia, PA, 2009,12-1 to 12-6. Vadivelu N, Whitney C, Acute Pain Management in: Urman RD and Ehrenfield J. (eds) Pocket Anesthesia. Lippincott Williams & Wilkins, Philadelphia, PA, 2009,12-1 to 12-6.
  • Vadivelu N, Whitney C, Chronic Pain Management in: Urman RD and Ehrenfield J. (eds) Pocket Anesthesia, Lippincott Williams & Wilkins, Philadelphia, PA, 2009, 29-1 to 29-7Vadivelu N, Whitney C, Chronic Pain Management in: Urman RD and Ehrenfield J. (eds) Pocket Anesthesia, Lippincott Williams & Wilkins, Philadelphia, PA, 2009, 29-1 to 29-7
  • Vadivelu N, Whitney C, Sinatra RS. Pain Pathways and Acute Pain Processing in: Sinatra, R, DeLeon-Cassasola O, Viscusi E, Ginsberg B and McQuay H (eds) Acute Pain Management. Cambridge University Press, New York, NY, 2009, 3-20. Vadivelu N, Whitney C, Sinatra RS. Pain Pathways and Acute Pain Processing in: Sinatra, R, DeLeon-Cassasola O, Viscusi E, Ginsberg B and McQuay H (eds) Acute Pain Management. Cambridge University Press, New York, NY, 2009, 3-20.
  • Dabu-Bondoc S, Zhang R, Vadivelu N. Managing Pain in the Addicted Patient in: Essentials in Pain Management, Springer Science and Business Media, New York, NY, 2011, 671-697..Dabu-Bondoc S, Zhang R, Vadivelu N. Managing Pain in the Addicted Patient in: Essentials in Pain Management, Springer Science and Business Media, New York, NY, 2011, 671-697..
  • Vadivelu N, Urman RD. Fibromyalgia, Arthritic and Myofascial Pain: Vadivelu N, Hines RL, Urman RD (eds) Essentials in Pain Management, Springer Science and Business Media, New York, NY, 2011, 557-556. Vadivelu N, Urman RD. Fibromyalgia, Arthritic and Myofascial Pain: Vadivelu N, Hines RL, Urman RD (eds) Essentials in Pain Management, Springer Science and Business Media, New York, NY, 2011, 557-556.
  • Vadivelu N. Buprenorphine, Intravenous, Neuraxial and Transdermal Applications in: Sinatra RS, Jahr, JS and Watkins-Pitchford JM (eds) The Essence of Analgesia and Analgesics, Cambridge University Press, Cambridge, UK, 2011, 157-160 Vadivelu N. Buprenorphine, Intravenous, Neuraxial and Transdermal Applications in: Sinatra RS, Jahr, JS and Watkins-Pitchford JM (eds) The Essence of Analgesia and Analgesics, Cambridge University Press, Cambridge, UK, 2011, 157-160
  • Vadivelu N, Whitney C. Acute and Postoperative Pain Management In: Vadivelu N, Urman R, (eds) Pocket Pain, Lippincott, Williams and Wilkins, Philadelphia, PA, 2011, Chapter 19, pp. 1 – 9..Vadivelu N, Whitney C. Acute and Postoperative Pain Management In: Vadivelu N, Urman R, (eds) Pocket Pain, Lippincott, Williams and Wilkins, Philadelphia, PA, 2011, Chapter 19, pp. 1 – 9..
  • Mitra S, Vadivelu N. Pain Anatomy and Physiology In: Vadivelu N, Urman R, (eds) Pocket Pain, Lippincott, Williams and Wilkins, Philadelphia, PA, 2011, Chapter 2, pp. 1 – 5.65. Mitra S, Vadivelu N. Pain Anatomy and Physiology In: Vadivelu N, Urman R, (eds) Pocket Pain, Lippincott, Williams and Wilkins, Philadelphia, PA, 2011, Chapter 2, pp. 1 – 5.65.
  • Mitra S, Vadivelu N. Mechanisms of Acute and Chronic Pain In: Vadivelu N, Urman R, (eds) Pocket Pain, Lippincott, Williams and Wilkins, Philadelphia, PA, 2011, Chapter 3, pp. 1 – 5 Mitra S, Vadivelu N. Mechanisms of Acute and Chronic Pain In: Vadivelu N, Urman R, (eds) Pocket Pain, Lippincott, Williams and Wilkins, Philadelphia, PA, 2011, Chapter 3, pp. 1 – 5
  • Kunnupurath S, Vadivelu N. Neuraxial Blockade: Epidural Anesthesia In: Kaye A, Vadivelu N, Urman R (eds) Essentials in Regional Anesthesia. Springer Press, New York, NY, 2012, 293-338. Kunnupurath S, Vadivelu N. Neuraxial Blockade: Epidural Anesthesia In: Kaye A, Vadivelu N, Urman R (eds) Essentials in Regional Anesthesia. Springer Press, New York, NY, 2012, 293-338.
  • Mitra S, Vadivelu N. Multidisciplinary Approach and Coordination of Care In: Vadivelu N, Berger JM, Kaye AD (eds) Essentials of Palliative Care. Springer Press,New York, NY, 2013, 7-21. Mitra S, Vadivelu N. Multidisciplinary Approach and Coordination of Care In: Vadivelu N, Berger JM, Kaye AD (eds) Essentials of Palliative Care. Springer Press,New York, NY, 2013, 7-21.
  • Mitra S, Vadivelu N. Guidance with Complex Treatment Choices In: Vadivelu N, Berger JM, Kaye AD (eds) Essentials of Palliative Care. Springer Press, New York,NY, 2013, 89-105Mitra S, Vadivelu N. Guidance with Complex Treatment Choices In: Vadivelu N, Berger JM, Kaye AD (eds) Essentials of Palliative Care. Springer Press, New York,NY, 2013, 89-105
  • Mitra S, Ahuja V,Vadivelu N. Mechanisms of Pain In: Urman R, Vadivelu N (eds)Perioperative Pain Management. Oxford University Press, New York, NY, 2013, pp 11-19. Mitra S, Ahuja V,Vadivelu N. Mechanisms of Pain In: Urman R, Vadivelu N (eds)Perioperative Pain Management. Oxford University Press, New York, NY, 2013, pp 11-19.
  • Kahn E, Vadivelu N. Cocaine abuse In: Kaye AD, Vadivelu N, Urman R (eds) Substance Abuse: Inpatient and Outpatient Management for Every Clinician, SpringerPress, New York, NY, 2014, pp 143-154.48. Kahn E, Vadivelu N. Cocaine abuse In: Kaye AD, Vadivelu N, Urman R (eds) Substance Abuse: Inpatient and Outpatient Management for Every Clinician, SpringerPress, New York, NY, 2014, pp 143-154.48.
  • Vadivelu N, Gowda AM, Thorp S, Kai A, Vadivelu A, Dabu-bondoc S. Nociceptive Chemical Mediators in Oral Inflammation In: Vadivelu N, Kaye AD (eds) Orofacial pain – A Clinician’s Manual, Springer International Press, Switzerland, 2014 Vadivelu N, Gowda AM, Thorp S, Kai A, Vadivelu A, Dabu-bondoc S. Nociceptive Chemical Mediators in Oral Inflammation In: Vadivelu N, Kaye AD (eds) Orofacial pain – A Clinician’s Manual, Springer International Press, Switzerland, 2014
  • Vadivelu N, Huang Y, Vadivelu A, Dabu-Bondoc S. The Neurobiology of OrofacialPain In: Vadivelu N, Kai A, Vadivelu A (eds) Orofacial Pain – A Clinician’s Manual, Springer Press, New York, NY, 2014 Vadivelu N, Huang Y, Vadivelu A, Dabu-Bondoc S. The Neurobiology of OrofacialPain In: Vadivelu N, Kai A, Vadivelu A (eds) Orofacial Pain – A Clinician’s Manual, Springer Press, New York, NY, 2014
  • Basu D, Mitra S, Vadivelu N. Tobacco In: Kaye AD, Vadivelu N, Urman R (eds) Substance Abuse: Inpatient and Outpatient Management for Every Clinician, SpringerPress, New York, NY, 2014, pp 89-108.Basu D, Mitra S, Vadivelu N. Tobacco In: Kaye AD, Vadivelu N, Urman R (eds) Substance Abuse: Inpatient and Outpatient Management for Every Clinician, SpringerPress, New York, NY, 2014, pp 89-108.
  • Gevirtz C, Kaye AD, Vadivelu N. Post-operative Pain Control in Drug Abusing patients In: Kaye AD, Vadivelu N, Urman R (eds) Substance Abuse: Inpatient and Outpatient Management for Every Clinician, Springer Press, New York, NY, 2014,pp 379-388. Gevirtz C, Kaye AD, Vadivelu N. Post-operative Pain Control in Drug Abusing patients In: Kaye AD, Vadivelu N, Urman R (eds) Substance Abuse: Inpatient and Outpatient Management for Every Clinician, Springer Press, New York, NY, 2014,pp 379-388.
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