Hajime Tokuno, MD
Research & Publications
Biography
News
Research Summary
I have an interest in studying patients with chronic pain syndromes. I focus on subjects with myofascial pain syndromes, neuropathic pain and complex regional pain syndrome (a.k.a. reflex sympathetic dystrophy).
Extensive Research Description
1. The effect of botulinum toxins on chronic myofascial pain syndromes. We are actively enrolling in one study looking at the benefits of botulinum toxins for individuals with chronic neck or chronic back pain. The concept behind the use of botulinum toxins in subjects with chronic myofascial pain is based a belief that a significant part of the pain is due to unregulated muscular activity in the setting of mechanical injury.
2. The development of novel pain scores for tracking chronic pain conditions. We are developing several new pathways of pain scoring that may better predict outcomes in new treatment possibilities.
3. The clinical uses of infrared thermography in diagnosing and assessing severity of nerve or muscle injuries.
Research Interests
Back Pain; Musculoskeletal Diseases; Myofascial Pain Syndromes; Neuromuscular Diseases; Peripheral Nervous System Diseases; Neck Pain; Muscular Disorders, Atrophic
Research Image
Thermographic image of a plegic right leg
Selected Publications
- Molecular Reconstruction of Nodes of Ranvier after Remyelination by Transplanted Olfactory Ensheathing Cells in the Demyelinated Spinal CordSasaki M, Black JA, Lankford KL, Tokuno HA, Waxman SG, Kocsis JD. Molecular Reconstruction of Nodes of Ranvier after Remyelination by Transplanted Olfactory Ensheathing Cells in the Demyelinated Spinal Cord Journal Of Neuroscience 2006, 26: 1803-1812. PMID: 16467529, PMCID: PMC2605396, DOI: 10.1523/jneurosci.3611-05.2006.
- Local anesthetic effects of cocaethylene and isopropylcocaine on rat peripheral nervesTokuno HA, Bradberry CW, Everill B, Agulian SK, Wilkes S, Baldwin RM, Tamagnan GD, Kocsis JD. Local anesthetic effects of cocaethylene and isopropylcocaine on rat peripheral nerves Brain Research 2004, 996: 159-167. PMID: 14697493, DOI: 10.1016/j.brainres.2003.10.024.