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Denise Esserman, PhD

Professor of Biostatistics

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Denise Esserman, PhD

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Research Summary

My research has mainly been collaborative, such that any methods work that I have done has developed from these relationships. For example, in working with a scholar on her K23 award, we realized there were no sample size formulas for randomized control trials with educational interventions in which one arm is randomized to a group setting while the other is left in clusters of size 1, and thus developed and published this methodology. I am currently interested in methods related to clustered randomized trials, and the impact of the ICC and other factors on calculating sample size. I enjoy working on problems with a very applied focus.

Specialized Terms: Applied Survey Sampling; Survey Sampling; Longitudinal Data; Clustered Clinical Trials; Adherence Data

Coauthors

Research Interests

Longitudinal Studies; Public Health; Sampling Studies; Randomized Controlled Trial; Biostatistics

Selected Publications

  • Rental assistance improves food security and nutrition: An analysis of National Survey DataDenary W, Fenelon A, Whittaker S, Esserman D, Lipska K, Keene D. Rental assistance improves food security and nutrition: An analysis of National Survey Data Preventive Medicine 2023, 169: 107453. PMID: 36813247, DOI: 10.1016/j.ypmed.2023.107453.
  • A qualitative study identifying challenges resulting from complex evidence on lifestyle factors and cancer: perspectives from Black and Latina cancer survivors and healthcare providersPichardo M, Irwin M, Sanft T, Ferrucci L, Ginader A, Nguyen T, Esserman D, Cartmel B, Molina Y. A qualitative study identifying challenges resulting from complex evidence on lifestyle factors and cancer: perspectives from Black and Latina cancer survivors and healthcare providers Supportive Care In Cancer 2023, 31: 111. PMID: 36633678, PMCID: PMC9912693, DOI: 10.1007/s00520-022-07539-9.
  • Taking a chance: How likely am I to receive my preferred treatment in a clinical trial?Walter S, Blaha O, Esserman D. Taking a chance: How likely am I to receive my preferred treatment in a clinical trial? Statistical Methods In Medical Research 2023, 32: 572-592. PMID: 36628522, PMCID: PMC9983058, DOI: 10.1177/09622802221146305.
  • Association Between Alcohol Use Disorder and Receipt of Direct-Acting Antiviral Hepatitis C Virus TreatmentHaque L, Fiellin D, Tate J, Esserman D, Bhattacharya D, Butt A, Crystal S, Edelman E, Gordon A, Lim J, Tetrault J, Williams E, Bryant K, Cartwright E, Rentsch C, Justice A, Re V, McGinnis K. Association Between Alcohol Use Disorder and Receipt of Direct-Acting Antiviral Hepatitis C Virus Treatment JAMA Network Open 2022, 5: e2246604. PMID: 36515952, DOI: 10.1001/jamanetworkopen.2022.46604.
  • Contingency management and pre-exposure prophylaxis adherence support services (CoMPASS): A hybrid type 1 effectiveness-implementation study to promote HIV risk reduction among people who inject drugsSung M, Viera A, Esserman D, Tong G, Davidson D, Aiudi S, Bailey G, Buchanan A, Buchelli M, Jenkins M, John B, Kolakowski J, Lame A, Murphy S, Porter E, Simone L, Paris M, Rash C, Edelman E. Contingency management and pre-exposure prophylaxis adherence support services (CoMPASS): A hybrid type 1 effectiveness-implementation study to promote HIV risk reduction among people who inject drugs Contemporary Clinical Trials 2022, 125: 107037. PMID: 36460267, DOI: 10.1016/j.cct.2022.107037.
  • Simulating time-to-event data subject to competing risks and clustering: A review and synthesis.Meng C, Esserman D, Li F, Zhao Y, Blaha O, Lu W, Wang Y, Peduzzi P, Greene E. Simulating time-to-event data subject to competing risks and clustering: A review and synthesis. Statistical Methods In Medical Research 2022, 9622802221136067. PMID: 36412111, DOI: 10.1177/09622802221136067.
  • Preliminary analysis of self-reported quality health indicators of patients on opioid agonist therapy at specialty and primary care clinics in Ukraine: A randomized control trialPashchenko O, Bromberg D, Dumchev K, LaMonaca K, Pykalo I, Filippovych M, Esserman D, Polonsky M, Galvez de Leon S, Morozova O, Dvoriak S, Altice F. Preliminary analysis of self-reported quality health indicators of patients on opioid agonist therapy at specialty and primary care clinics in Ukraine: A randomized control trial PLOS Global Public Health 2022, 2: e0000344. DOI: 10.1371/journal.pgph.0000344.
  • Rejection sensitivity and sexual minority men’s social anxiety disorder: The moderating role of sexual identity strengthMaiolatesi A, Wang K, Burton C, Harkness A, Esserman D, Safren S, Pachankis J. Rejection sensitivity and sexual minority men’s social anxiety disorder: The moderating role of sexual identity strength Self And Identity 2022, 1-29. DOI: 10.1080/15298868.2022.2125062.
  • Regression methods for the appearances of extremes in climate dataYu C, Blaha O, Kane M, Wei W, Esserman D, Zelterman D. Regression methods for the appearances of extremes in climate data Environmetrics 2022, 33 DOI: 10.1002/env.2764.
  • COVID-19 Pandemic as a Change Agent in the Structure and Practice of Statistical Consulting CentersLee S, Bagiella E, Vaughan R, Govindarajulu U, Christos P, Esserman D, Zhong H, Kim M. COVID-19 Pandemic as a Change Agent in the Structure and Practice of Statistical Consulting Centers The American Statistician 2022, 76: 152-158. DOI: 10.1080/00031305.2021.2023045.
  • preference : An R Package for Two-Stage Clinical Trial Design Accounting for Patient PreferenceCameron B, Kane M, Esserman D. preference : An R Package for Two-Stage Clinical Trial Design Accounting for Patient Preference Journal Of Statistical Software 2020, 94 DOI: 10.18637/jss.v094.c02.
  • HOSPITAL VARIATIONS IN TROPONIN ORDERING AND ITS ASSOCIATION WITH DOWNSTREAM RESOURCE UTILIZATION WITHIN THE VETERANS HEALTH ADMINISTRATIONChui P, Bastian L, Gandhi P, Esserman D, Miller E, Hauser R. HOSPITAL VARIATIONS IN TROPONIN ORDERING AND ITS ASSOCIATION WITH DOWNSTREAM RESOURCE UTILIZATION WITHIN THE VETERANS HEALTH ADMINISTRATION Journal Of The American College Of Cardiology 2019, 73: 178. DOI: 10.1016/s0735-1097(19)30786-7.
  • HOSPITAL VARIATIONS IN THE UTILIZATION OF CARDIAC STRESS TESTING FOR PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT WITHIN THE VETERANS HEALTH ADMINISTRATIONChui P, Hauser R, Miller E, Esserman D, Bastian L, Gandhi P. HOSPITAL VARIATIONS IN THE UTILIZATION OF CARDIAC STRESS TESTING FOR PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT WITHIN THE VETERANS HEALTH ADMINISTRATION Journal Of The American College Of Cardiology 2019, 73: 177. DOI: 10.1016/s0735-1097(19)30785-5.
  • 2224. Receipt and Virologic Outcomes of HCV Direct-Acting Antivirals by Alcohol Use and HIV StatusCartwright E, Rentsch C, Esserman D, Tate J, Fiellin D, Lo Re V, Justice A, . 2224. Receipt and Virologic Outcomes of HCV Direct-Acting Antivirals by Alcohol Use and HIV Status Open Forum Infectious Diseases 2018, 5: s657-s658. PMCID: PMC6253010, DOI: 10.1093/ofid/ofy210.1877.
  • STRIDE: EXPERIMENTAL AND STATISTICAL DESIGN CONSIDERATIONSTravison T, Miller M, Allore H, Dzuira J, Esserman D, Greene E. STRIDE: EXPERIMENTAL AND STATISTICAL DESIGN CONSIDERATIONS Innovation In Aging 2017, 1: 1007-1007. PMCID: PMC6185674, DOI: 10.1093/geroni/igx004.3656.
  • PARTICIPANT RANDOMIZATION IN COMPLEX TRIAL DESIGNSTravison T, Esserman D, Greene E, Allore H. PARTICIPANT RANDOMIZATION IN COMPLEX TRIAL DESIGNS Innovation In Aging 2017, 1: 658-658. PMCID: PMC6247269, DOI: 10.1093/geroni/igx004.2334.
  • ANALYSIS OF TRIALS WITH MULTI-LEVEL CLUSTERING, RECURRENT EVENTS AND COMPETING RISKSAllore H, Jung T, Esserman D, Peduzzi P. ANALYSIS OF TRIALS WITH MULTI-LEVEL CLUSTERING, RECURRENT EVENTS AND COMPETING RISKS Innovation In Aging 2017, 1: 658-658. PMCID: PMC6247167, DOI: 10.1093/geroni/igx004.2335.
  • Mo1383 Weight Change After Receipt of Direct-Acting Antiviral Agents for Hepatitis CDo A, Esserman D, Tate J, Njei B, Levin F, Lim J, Taddei T, Justice A. Mo1383 Weight Change After Receipt of Direct-Acting Antiviral Agents for Hepatitis C Gastroenterology 2017, 152: s1163. DOI: 10.1016/s0016-5085(17)33893-3.
  • 807 Variability of Hepatitis C Screening in Birth Age Cohort U.S. Veterans Born 1945-1965: National Analysis of 4.2 Million Veterans 2000-2013Sarkar S, Esserman D, Levin F, Justice A, Lim J. 807 Variability of Hepatitis C Screening in Birth Age Cohort U.S. Veterans Born 1945-1965: National Analysis of 4.2 Million Veterans 2000-2013 Gastroenterology 2015, 148: s-997. DOI: 10.1016/s0016-5085(15)33407-7.
  • The Flipped ClassroomMcLaughlin JE, Roth MT, Glatt DM, Gharkholonarehe N, Davidson CA, Griffin LM, Esserman DA, Mumper RJ. The Flipped Classroom Academic Medicine 2014, 89: 236-243. PMID: 24270916, DOI: 10.1097/acm.0000000000000086.
  • Physician Decision Making for Colorectal Cancer Screening in the ElderlyLewis CL, Esserman D, DeLeon C, Pignone MP, Pathman DE, Golin C. Physician Decision Making for Colorectal Cancer Screening in the Elderly Journal Of General Internal Medicine 2013, 28: 1202-1207. PMID: 23539281, PMCID: PMC3744317, DOI: 10.1007/s11606-013-2393-5.
  • Sample size estimation in educational intervention trials with subgroup heterogeneity in only one armEsserman D, Zhao Y, Tang Y, Cai J. Sample size estimation in educational intervention trials with subgroup heterogeneity in only one arm Statistics In Medicine 2012, 32: 2140-2154. PMID: 23172724, PMCID: PMC3615113, DOI: 10.1002/sim.5678.
  • A Novel Canine Model of Immune ThrombocytopeniaLeVine D, Birkenheuer A, Brooks M, Nordone S, Bellinger D, Jones S, Fischer T, Esserman D, Oglesbee S, Key N. A Novel Canine Model of Immune Thrombocytopenia Blood 2012, 120: 3326-3326. DOI: 10.1182/blood.v120.21.3326.3326.
  • Immunologic Phenotype Of GRK3-null Mice At Baseline And In Inflammatory DiseaseTimoshchencko R, Rothlein L, McGinnis M, Foreman O, Esserman D, Lee D, Patel D, Siderovski D, Tarrant T. Immunologic Phenotype Of GRK3-null Mice At Baseline And In Inflammatory Disease Journal Of Allergy And Clinical Immunology 2012, 129: ab213. DOI: 10.1016/j.jaci.2011.12.081.
  • Older US Emergency Department Patients Are Less Likely to Receive Pain Medication Than Younger Patients: Results From a National SurveyPlatts-Mills TF, Esserman DA, Brown DL, Bortsov AV, Sloane PD, McLean SA. Older US Emergency Department Patients Are Less Likely to Receive Pain Medication Than Younger Patients: Results From a National Survey Annals Of Emergency Medicine 2011, 60: 199-206. PMID: 22032803, PMCID: PMC3338876, DOI: 10.1016/j.annemergmed.2011.09.014.
  • The use of complete-case and multiple imputation-based analyses in molecular epidemiology studies that assess interaction effectsDesai M, Esserman DA, Gammon MD, Terry MB. The use of complete-case and multiple imputation-based analyses in molecular epidemiology studies that assess interaction effects Epidemiologic Perspectives & Innovations 2011, 8: 1-17. PMID: 21978450, PMCID: PMC3217865, DOI: 10.1186/1742-5573-8-5.
  • Sustained Body Mass Index Changes One and Two Years Post MATCH: A School-Based Wellness Intervention in AdolescentsLazorick S, Hardison G, Esserman D, Perrin E. Sustained Body Mass Index Changes One and Two Years Post MATCH: A School-Based Wellness Intervention in Adolescents Childhood Obesity 2011, 7: 372-378. DOI: 10.1089/chi.2011.0043.
  • S100A9 is not essential for disease expression in an acute (K/BxN) or chronic (CIA) model of inflammatory arthritisRampersad R, Esserman D, McGinnis M, Lee D, Patel D, Tarrant T. S100A9 is not essential for disease expression in an acute (K/BxN) or chronic (CIA) model of inflammatory arthritis Scandinavian Journal Of Rheumatology 2009, 1-5. DOI: 10.1080/03009740902895743.
  • 1: Cholesterol Screening Does Not Motivate Obese Adolescents to Decrease Their BMIDoshi N, Perrin E, Esserman D, Steiner M. 1: Cholesterol Screening Does Not Motivate Obese Adolescents to Decrease Their BMI Journal Of Adolescent Health 2008, 42: 8-9. DOI: 10.1016/j.jadohealth.2007.11.028.
  • P2-159 Birthweight, postnatal growth, and age at menarcheFerris J, Esserman D, Flom J, Terry M. P2-159 Birthweight, postnatal growth, and age at menarche Early Human Development 2007, 83: s174. DOI: 10.1016/s0378-3782(07)70492-9.
  • Maternal, Birth, and Early-Life Influences on Adult Body Size in WomenTerry MB, Wei Y, Esserman D. Maternal, Birth, and Early-Life Influences on Adult Body Size in Women American Journal Of Epidemiology 2007, 166: 5-13. PMID: 17470452, DOI: 10.1093/aje/kwm094.
  • Terry et al. Respond to “Antecedents of Obesity”Terry M, Wei Y, Esserman D. Terry et al. Respond to “Antecedents of Obesity” American Journal Of Epidemiology 2007, 166: 17-18. DOI: 10.1093/aje/kwm095.
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