Youngsun Cho, MD, PhD
Assistant ProfessorDownloadHi-Res Photo
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Child Study Center
Fully Joint
Psychiatry
Fully Joint
About
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Titles
Assistant Professor
Biography
Dr. Youngsun T. Cho is an Assistant Professor in the Child Study Center and Department of Psychiatry at Yale University. She is a child, adolescent and adult psychiatrist. She holds an MD/PhD degree from the University of Rochester, and completed dissertation work on amygdala neuroanatomy and reward processing using fMRI. She completed psychiatry residency in the Neuroscience Research Training Program (NRTP) at Yale, and a child and adolescent psychiatry fellowship at the Yale Child Study Center.
Her current research focuses on the development of cognitive and motivational brain circuits in adolescents with depression and adolescents with schizophrenia using fMRI, and pharmacologic neuroimaging to identify mechanisms of potential treatments. Her work is funded by the NIMH, and the Brain and Behavior Research Foundation.
Last Updated on January 04, 2025.
Appointments
Child Study Center
Assistant ProfessorFully JointPsychiatry
Assistant ProfessorFully Joint
Other Departments & Organizations
- Center for Brain & Mind Health
- Child Study Center
- Cho Lab
- Clinical Neuroscience Research Unit
- Division of Neurocognition, Neurocomputation & Neurogenetics
- Interdepartmental Neuroscience Program
- Janeway Society
- MR Core
- Neuroscience Research Training Program (NRTP)
- Neuroscience Track
- Psychiatry
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)
- Yale Medicine
- Yale New Haven Health System
Education & Training
- PhD
- Univ of Rochester School of Medicine & Dentistry (2013)
- MD
- Univ of Rochester School of Medicine & Dentistry (2013)
- MS
- University of Rochester School of Medicine & Dentistry (2009)
- BS
- Massachusetts Institute of Technology (2005)
Research
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Overview
Medical Research Interests
Amygdala; Child Development; Cognition; Depression; Motivation; Neuroimaging; Schizophrenia
ORCID
0000-0001-8639-3869- View Lab Website
Cho Lab
Research at a Glance
Yale Co-Authors
Frequent collaborators of Youngsun Cho's published research.
Alan Anticevic
Former YSMZailyn Tamayo
Clara Fonteneau, PhD
Albert Powers, MD, PhD
Scott Woods, MD
Godfrey Pearlson, MA, MBBS
Publications
2026
Untangling relationships between cognitive development and child and adolescent mental health: Findings from the ABCD Study
Chen Y, Agrawal S, Anokhin A, Luciana M, Gee D, Cho Y. Untangling relationships between cognitive development and child and adolescent mental health: Findings from the ABCD Study. Developmental Cognitive Neuroscience 2026, 80: 101772. PMID: 42372692, PMCID: PMC13330672, DOI: 10.1016/j.dcn.2026.101772.Peer-Reviewed Original ResearchCitationsAltmetricRegional, functional and transcriptomic decoding of multidimensional brain structure alterations in obsessive-compulsive disorder
Cardoso Saraiva L, Sato J, Sebenius I, Dzinalija N, del Río-Torné C, Godinho F, Lopes A, Fernandez T, Lima M, Ramos V, Iglesio R, Abe Y, Alonso P, Ameis S, Anticevic A, Araújo A, Arnold P, Balachander S, Banaj N, Batistuzzo M, Benedetti F, Bollettini I, Bravi B, Brennan B, Buitelaar J, Castelo-Branco M, Choi S, Costa A, Dallaspezia S, Denys D, Duarte I, Echevarria M, Eng G, Fernandes A, Feusner J, Figee M, Fitzsimmons S, Fontenelle L, Grazioplene R, Ha M, Hinojosa A, Hoexter M, Huijser C, Hu H, James A, Kim M, Kwon J, Lazaro L, Lochner C, Machado-Sousa M, van Marle H, Martínez-Zalacaín I, Mataix-Cols D, Menchón J, Minuzzi L, Morgado P, Muñoz-Moreno E, Nakao T, Narayanaswamy J, Nurmi E, O’Neill J, Park I, Phillips M, Piacentini J, Picó-Pérez M, Piras F, Piras F, Postma T, Li C, Reddy J, van Rooij D, Sakai Y, de Salles Andrade J, Scheffler F, Shivakumar V, Soreni N, Stern E, van der Straten A, Thomopoulos S, Tomiyama H, Tovar-Moll F, Vecchio D, Veltman D, Venkatasubramanian G, Vriend C, Wang Z, van der Werf Y, van Wingen G, Zhao Q, Charney A, Cho Y, Shavitt R, Pushkarskaya H, Soriano-Mas C, Romero-Garcia R, Thompson P, Stein D, van den Heuvel O, Winkler A, Miguel Filho E, Pittenger C, Cappi C. Regional, functional and transcriptomic decoding of multidimensional brain structure alterations in obsessive-compulsive disorder. Nature Communications 2026 PMID: 42343090, DOI: 10.1038/s41467-026-74153-2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricQuNex recipes: Executable, human-readable workflows for reproducible neuroimaging research
Demšar J, Kraljič A, Matkovič A, Brege S, Pan L, Tamayo Z, Fonteneau C, Helmer M, Ji J, Anticevic A, Korponay C, Salavrakos M, Drucker D, Glasser M, Nickerson L, Cho Y, Repovš G. QuNex recipes: Executable, human-readable workflows for reproducible neuroimaging research. Imaging Neuroscience 2026, 4: imag.a.1274. PMID: 42312086, PMCID: PMC13271150, DOI: 10.1162/imag.a.1274.Peer-Reviewed Original ResearchAltmetricUsing games to identify adolescents at risk for substance misuse—a proof-of-concept study
Aneni K, Chen C, Meyer J, Mavromichali C, Scaria E, Liu G, Cho Y, Fiellin L. Using games to identify adolescents at risk for substance misuse—a proof-of-concept study. Frontiers In Health Services 2026, 6: 1781703. PMID: 42148446, PMCID: PMC13176319, DOI: 10.3389/frhs.2026.1781703.Peer-Reviewed Original ResearchEstablishment of the Society for the Advancement of Neuroscience and Psychiatry in Residency Research Education (Synapse): An Organization to Promote Research Training in Residency
Ward H, Ajilore O, Cho Y, Cooper J, Dunlop B, Miller A, Philip N, Pruett B, Taylor S, Tyrka A, Vogel A, Goldsmith D. Establishment of the Society for the Advancement of Neuroscience and Psychiatry in Residency Research Education (Synapse): An Organization to Promote Research Training in Residency. Academic Psychiatry 2026, 1-5. PMID: 41781634, DOI: 10.1007/s40596-026-02312-0.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAltmetric
2025
A translational neuroscience & computational evaluation of a D1R partial agonist for schizophrenia (TRANSCENDS): Rationale and study design of a brain-based clinical trial
Fonteneau C, Tamayo Z, Price A, Pan L, Afriyie-Agyemang Y, Agrawal S, Butler A, Cail C, Calkins M, Chakilam A, Forselius-Bielen K, Fram G, Frazier A, Gil R, Govil P, Gray D, Grinband J, Gur R, Haubold N, Heffernan Z, Heneks M, Kegeles L, Kohler C, Lin C, Lu J, Mayer M, Pham P, Perlman G, Rahmati M, Ranganathan M, Santamauro N, Schutte C, Selloni A, Van Snellenberg J, Surti T, Wolf D, Zharyy C, Group T, Abi-Dargham A, Gur R, Lieberman J, Kantrowitz J, Anticevic A, Cho Y, Krystal J. A translational neuroscience & computational evaluation of a D1R partial agonist for schizophrenia (TRANSCENDS): Rationale and study design of a brain-based clinical trial. Journal Of Psychiatric Research 2025, 194: 196-210. PMID: 41519104, PMCID: PMC13138834, DOI: 10.1016/j.jpsychires.2025.12.020.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPrediction of antipsychotic medication inception in antipsychotic-naive youth at clinical high risk for psychosis
Mukhtar H, Zhou D, Farina E, Saxena A, Cahill J, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshwan M, Mathalon D, Perkins D, Stone W, Cho Y, Powers A, Walker E, Woods S. Prediction of antipsychotic medication inception in antipsychotic-naive youth at clinical high risk for psychosis. Psychological Medicine 2025, 55: e241. PMID: 40842369, PMCID: PMC12404330, DOI: 10.1017/s0033291725101372.Peer-Reviewed Original ResearchCitationsAltmetricBaseline Clinical Characterization of Participants in the Accelerating Medicines Partnership Schizophrenia Program
Addington J, Liu L, Chu M, Jungert K, Penzel N, Pasternak O, Farina E, Carrion R, Corcoran C, Mittal V, Strauss G, Yung A, Alameda L, Arango C, Borders O, Bouix S, Breitborde N, Broome M, Cadenhead K, Castillo-Passi R, Chen E, Choi J, Coleman M, Conus P, Diaz-Caneja C, Ellman L, Poli P, Gaspar P, Gerber C, Glenthøj L, Horton L, Hui C, Kambeitz J, Kambeitz-Ilankovic L, Kapur T, Kelly S, Kerr M, Keshavan M, Kim M, Kim S, Koutsouleris N, Kwon J, Langbein K, Lewandowski K, Mamah D, Marcy P, Mathalon D, Mourgues C, Nordentoft M, Nunez A, Pearlson G, Perez J, Perkins D, Powers A, Rogers J, Sabb F, Schiffman J, Seitz-Holland J, Shah J, Silverstein S, Smesny S, Stone W, Thompson J, Upthegrove R, Verma S, Wang J, Wolf D, Zhang T, Addamo L, Buccilli K, Dwyer D, Todd S, Cho Y, Fontenau C, Tamayo Z, Bearden C, Kane J, McGorry P, Kahn R, Shenton M, Woods S, Barnaby A, Calkins M. Baseline Clinical Characterization of Participants in the Accelerating Medicines Partnership Schizophrenia Program. Schizophrenia Bulletin Open 2025, 6: sgaf012. PMID: 40861307, PMCID: PMC12377803, DOI: 10.1093/schizbullopen/sgaf012.Peer-Reviewed Original ResearchCitationsAltmetric
2024
Individual differences in spatial working memory strategies differentially reflected in the engagement of control and default brain networks
Suljič N, Kraljič A, Rahmati M, Cho Y, Ozimič A, Murray J, Anticevic A, Repovš G. Individual differences in spatial working memory strategies differentially reflected in the engagement of control and default brain networks. Cerebral Cortex 2024, 34: bhae350. PMID: 39214852, PMCID: PMC11364466, DOI: 10.1093/cercor/bhae350.Peer-Reviewed Original ResearchCitationsThe Habenula and Our Drive for Food
Cho Y. The Habenula and Our Drive for Food. Biological Psychiatry 2024, 95: 912-913. PMID: 38692797, DOI: 10.1016/j.biopsych.2024.03.006.Peer-Reviewed Original ResearchMeSH Keywords
Clinical Trials
Current Trials
Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
IRB ID2000023688RoleSub InvestigatorPrimary Completion Date07/31/2024Recruiting ParticipantsGenderBothAge18 years - 65 yearsBiomarkers of Clinical Subtype and Treatment Response in Obsessive-Compulsive Disorder
IRB ID0803003626RoleSub InvestigatorPrimary Completion Date04/19/2025Recruiting ParticipantsGenderBothAge18 years - 70 years
News
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News
- February 07, 2025
2024-2025 YCSC Postdoctoral Scholar Travel Awardees Announced
- November 13, 2024
Woods, Cho Awarded $76M NIH Grant to Conduct Clinical Trials for Youth at Risk for Schizophrenia
- April 12, 2024
Spring 2024 postgraduate associate travel award recipients announced
- January 30, 2024
ASCI Recognizes Early-career Yale Faculty and Trainees
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