Dermatology News & Information
Faculty Retreat
The Department of Dermatology faculty retreat took place on May 29 in the Klein Biology Tower. In addition to enjoying lunch, games, refreshments, and massages, faculty heard presentations by Brian Ferguson, Founder of Arena Labs, and Benjamin Doolittle, MD, MDiv, a practicing physician and minister. With Dr. Doolittle, faculty read and discussed a John Stone poem, Gaudeamus igitur. Brian Ferguson discussed how physicians can flourish, with techniques that other high-stress professions (like the NAVY SEALs) are taught during their training.
Junior Faculty Family Fun Event
Yale Dermatology junior faculty and families gathered for a backyard barbecue in May.
2024 Residents and Fellows Graduation Ceremony
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News
- Health Headlines: How to tell if a spot on your skin is concerningSource: WTNH News 8
- Your Complete Melanoma Resource GuideSource: HealthCentral
- Serendipity in ActionSource: Yale Medicine Magazine
- Struggling with 'bacne?' New treatments can help an embarrassing problem.Source: The Washington Post
Publications
- Successful use of picosecond laser treatment for seborrheic keratosis in three Asian patientsSwallow M, Elgash M, Kim R, Suozzi K. Successful use of picosecond laser treatment for seborrheic keratosis in three Asian patients. JAAD Case Reports 2024, 48: 46-48. PMID: 38774669, PMCID: PMC11107074, DOI: 10.1016/j.jdcr.2024.04.006.
- Treatment of prolonged drug reaction with eosinophilia and systemic symptoms syndrome with dupilumab using a molecularly-guided approachValido K, Patel V, Murphy M, Junejo M, Patel D, Deutsch A, Turner N, Zaki T, King B, Damsky W, Nelson C. Treatment of prolonged drug reaction with eosinophilia and systemic symptoms syndrome with dupilumab using a molecularly-guided approach. JAAD Case Reports 2024, 48: 49-53. PMID: 38774671, PMCID: PMC11107093, DOI: 10.1016/j.jdcr.2024.03.020.
- The development of hair follicles and nailLee S, Platt S, Lim C, Ito M, Myung P. The development of hair follicles and nail. Developmental Biology 2024, 513: 3-11. PMID: 38759942, DOI: 10.1016/j.ydbio.2024.05.010.
- Triple Combination Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% for Acne: Efficacy and Safety from a Pooled Phase 3 AnalysisKircik L, Stein Gold L, Gold M, Weiss J, Harper J, Del Rosso J, Bunick C, Bhatia N, Tanghetti E, Eichenfield L, Baldwin H, Draelos Z, Callender V, Han G, Gooderham M, Sadick N, Lupo M, Lain E, Werschler W. Triple Combination Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% for Acne: Efficacy and Safety from a Pooled Phase 3 Analysis. Dermatology And Therapy 2024, 14: 1211-1227. PMID: 38724841, PMCID: PMC11116301, DOI: 10.1007/s13555-024-01155-7.
- Topical ruxolitinib for facial blaschkitis in an adolescentZarowin D, Provini L, Antaya R. Topical ruxolitinib for facial blaschkitis in an adolescent. Pediatric Dermatology 2024, 41: 938-939. PMID: 38716713, DOI: 10.1111/pde.15640.
- Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinomaTang H, Laskin W, Luan Y, McNiff J, Zhan H. Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinoma. Journal Of Cutaneous Pathology 2024, 51: 604-608. PMID: 38711196, DOI: 10.1111/cup.14639.
- Intravenous immunoglobulin-induced eczematous dermatitis treated with dupilumabSingh K, Breidbart R, Jaiswal A, Damsky W, Choate K, Vesely M. Intravenous immunoglobulin-induced eczematous dermatitis treated with dupilumab. JAAD Case Reports 2024, 49: 102-105. PMID: 38952857, PMCID: PMC11214983, DOI: 10.1016/j.jdcr.2024.05.002.
- Hyaluronic acid filler for lip augmentation in patients with systemic sclerosis: A prospective cohort studySwallow M, Elgash M, Kim R, Hinchcliff M, Suozzi K. Hyaluronic acid filler for lip augmentation in patients with systemic sclerosis: A prospective cohort study. JAAD Case Reports 2024, 49: 79-81. PMID: 38952859, PMCID: PMC11214978, DOI: 10.1016/j.jdcr.2024.05.006.
- Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activationXin T, Gallini S, Wei H, Gonzalez D, Matte-Martone C, Machida H, Fujiwara H, Pasolli H, Suozzi K, Gonzalez L, Regot S, Greco V. Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation. Nature Cell Biology 2024, 26: 859-867. PMID: 38689013, PMCID: PMC11519783, DOI: 10.1038/s41556-024-01413-y.
- Unveiling the secrets of vimentin filament architecture relevant to human diseaseLomakin I, Ho M, Bunick C. Unveiling the secrets of vimentin filament architecture relevant to human disease. Nature Structural & Molecular Biology 2024, 31: 849-851. PMID: 38684931, DOI: 10.1038/s41594-024-01301-x.
- Stigmatization and Mental Health Impact of Chronic Pediatric Skin DisordersPaller A, Rangel S, Chamlin S, Hajek A, Phan S, Hogeling M, Castelo-Soccio L, Lara-Corrales I, Arkin L, Lawley L, Funk T, Lopes F, Antaya R, Ramien M, Vivar K, Teng J, Coughlin C, Rehmus W, Gupta D, Bercovitch L, Stein S, Boull C, Tom W, Liang M, Hunt R, Luu M, Holland K, Schoch J, Cella D, Lai J, Griffith J. Stigmatization and Mental Health Impact of Chronic Pediatric Skin Disorders. JAMA Dermatology 2024, 160: 621-630. PMID: 38656377, PMCID: PMC11044010, DOI: 10.1001/jamadermatol.2024.0594.
- 08. Proteomic Profiling of Tumor Microenvironment In Desmoplastic Melanoma Using The Nanostring Geomx Digital Spatial ProfilerSu D, Galan A, Schoenfeld D, Ibrahim W, Cabrejo R, Baumann R, Rimm D, Khan S, Kluger H, Olino K, Clune J. 08. Proteomic Profiling of Tumor Microenvironment In Desmoplastic Melanoma Using The Nanostring Geomx Digital Spatial Profiler. Plastic & Reconstructive Surgery Global Open 2024, 12: 6-6. PMCID: PMC11041221, DOI: 10.1097/01.gox.0001015124.74133.52.
- Altered skin microbiome, inflammation, and JAK/STAT signaling in Southeast Asian ichthyosis patientsHo M, Nguyen H, Van Hoang M, Bui T, Vu B, Dinh T, Vo H, Blaydon D, Eldirany S, Bunick C, Bui C. Altered skin microbiome, inflammation, and JAK/STAT signaling in Southeast Asian ichthyosis patients. Human Genomics 2024, 18: 38. PMID: 38627868, PMCID: PMC11022333, DOI: 10.1186/s40246-024-00603-x.
- Crystal Structure of Bimekizumab Fab Fragment in Complex with IL-17F Provides Molecular Basis for Dual IL-17A and IL-17F InhibitionAdams R, Bunick C, Lawson A, Gomez B, Shaw S. Crystal Structure of Bimekizumab Fab Fragment in Complex with IL-17F Provides Molecular Basis for Dual IL-17A and IL-17F Inhibition. Journal Of Investigative Dermatology 2024, 144: 2581-2583.e2. PMID: 38631666, DOI: 10.1016/j.jid.2024.03.037.
- Characterizing interstitial lung disease in patients with psoriasis: a cross-sectional analysis in the National Institutes of Health’s All of Us Research ProgramShaw V, Damsky W, Homer R, Cohen J. Characterizing interstitial lung disease in patients with psoriasis: a cross-sectional analysis in the National Institutes of Health’s All of Us Research Program. Clinical And Experimental Dermatology 2024, 49: 1083-1084. PMID: 38618708, DOI: 10.1093/ced/llae132.
- Guselkumab for Pityriasis Rubra Pilaris and Dysregulation of IL-23/IL-17 and NFkB SignalingVelasco R, Shao C, Cutler B, Strunck J, Kent G, Cassidy P, Choate K, Greiling T. Guselkumab for Pityriasis Rubra Pilaris and Dysregulation of IL-23/IL-17 and NFkB Signaling. JAMA Dermatology 2024, 160: 641-645. PMID: 38598229, PMCID: PMC11007649, DOI: 10.1001/jamadermatol.2024.0257.
- Association of lichen planus with asthma and allergic rhinitis in the All of Us Research Program: a cross-sectional studyRichmond R, Murphy M, Edemobi P, Vesely M, Cohen J. Association of lichen planus with asthma and allergic rhinitis in the All of Us Research Program: a cross-sectional study. Clinical And Experimental Dermatology 2024, 49: 1067-1069. PMID: 38589773, PMCID: PMC11340807, DOI: 10.1093/ced/llae101.
- Cognitive Bias in the Patient Encounter: Part II. Debiasing using an adaptive toolboxKo C, Gehlhausen J, Cohen J, Jiang Y, Myung P, Croskerry P. Cognitive Bias in the Patient Encounter: Part II. Debiasing using an adaptive toolbox. Journal Of The American Academy Of Dermatology 2024 PMID: 38588820, DOI: 10.1016/j.jaad.2024.02.061.
- Cognitive Bias in the Patient Encounter: Part I. Background and significanceKo C, Gehlhausen J, Cohen J, Croskerry P. Cognitive Bias in the Patient Encounter: Part I. Background and significance. Journal Of The American Academy Of Dermatology 2024 PMID: 38588821, DOI: 10.1016/j.jaad.2024.01.091.
- Gene trajectory inference for single-cell data by optimal transport metricsQu R, Cheng X, Sefik E, Stanley III J, Landa B, Strino F, Platt S, Garritano J, Odell I, Coifman R, Flavell R, Myung P, Kluger Y. Gene trajectory inference for single-cell data by optimal transport metrics. Nature Biotechnology 2024, 1-11. PMID: 38580861, PMCID: PMC11452571, DOI: 10.1038/s41587-024-02186-3.
- Spiny Keratoderma: Clinical and Histopathological Findings in a Series of 3 CasesHanly A, Turner N, Ko C, Panse G. Spiny Keratoderma: Clinical and Histopathological Findings in a Series of 3 Cases. American Journal Of Dermatopathology 2024, 46: 439-442. PMID: 38574081, DOI: 10.1097/dad.0000000000002705.
- A Patient With Oral Discomfort and Reduced Oral ApertureChen G, Roy S, Cohen J. A Patient With Oral Discomfort and Reduced Oral Aperture. JAMA 2024, 331: 1147-1148. PMID: 38436993, DOI: 10.1001/jama.2023.25945.
- Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cellsBangert C, Alkon N, Chennareddy S, Arnoldner T, Levine J, Pilz M, Medjimorec M, Ruggiero J, Cohenour E, Jonak C, Damsky W, Griss J, Brunner P. Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cells. Nature Communications 2024, 15: 2839. PMID: 38565563, PMCID: PMC10987549, DOI: 10.1038/s41467-024-46540-0.
- Paradoxical PsoriasisAbdelghaffar M, Kottilil S, Murphy M, Cohen J, Damsky W. Paradoxical Psoriasis. Dermatologic Clinics 2024, 42: 471-480. PMID: 38796276, DOI: 10.1016/j.det.2024.02.011.
- In response to Reynolds et al’s “guidelines of care for the management of acne vulgaris”Issa N, Bunick C. In response to Reynolds et al’s “guidelines of care for the management of acne vulgaris”. Journal Of The American Academy Of Dermatology 2024, 91: e113-e114. PMID: 38909659, DOI: 10.1016/j.jaad.2024.05.091.
- Chart review study of real-world clinical outcomes in patients with cutaneous T-cell lymphoma treated with extracorporeal photopheresis in the US in 2017–2019Girardi M, Carlson K, Huang X, Corman S, Edmundson P, Schmier J, Kale H, Raina R, Foss F. Chart review study of real-world clinical outcomes in patients with cutaneous T-cell lymphoma treated with extracorporeal photopheresis in the US in 2017–2019. Journal Of Dermatological Treatment 2024, 35: 2360568. PMID: 38852942, DOI: 10.1080/09546634.2024.2360568.
- Psychosocial burden of autoimmune blistering diseases: A comprehensive survey studyWhite M, Hoffman V, Yale M, Strong R, Tomayko M. Psychosocial burden of autoimmune blistering diseases: A comprehensive survey study. Journal Of The European Academy Of Dermatology And Venereology 2024 PMID: 38837452, DOI: 10.1111/jdv.20156.
- Granuloma Annulare Exhibits Mixed Immune and Macrophage Polarization Profiles with Spatial TranscriptomicsMohanty C, Singh C, Daccache J, Damsky W, Kendziorski C, Yan D, Prasad A, Zhang D, Keenan T, Drolet B, Ahmad N, Shields B. Granuloma Annulare Exhibits Mixed Immune and Macrophage Polarization Profiles with Spatial Transcriptomics. Journal Of Investigative Dermatology 2024, 145: 109-121. PMID: 38844128, DOI: 10.1016/j.jid.2024.04.024.
- A Unique Presentation of Nodular Masses in Infancy.Velagala S, Heiden E, Lisse S, Wu H, Prior D, Chen G, Christison-Lagay E, Provini L, Antaya R, Spencer-Manzon M, Johnston L. A Unique Presentation of Nodular Masses in Infancy. NeoReviews 2024, 25: e370-e374. PMID: 38821908, DOI: 10.1542/neo.25-6-e370.
- A plasma-based proteomic platform for predicting clinical benefit from immune checkpoint inhibitors in multiple cancers.Sela I, Lahav C, Lowenthal G, Harel M, Elon Y, Yellin B, Dicker A, Halaban R, Marte J, Sznol M, Gulley J. A plasma-based proteomic platform for predicting clinical benefit from immune checkpoint inhibitors in multiple cancers. Journal Of Clinical Oncology 2024, 42: 2568-2568. DOI: 10.1200/jco.2024.42.16_suppl.2568.
- Association between psoriasis and obsessive-compulsive disorder: a case-control study in the All of Us research programCraver A, Chen G, Fan R, Levey D, Cohen J. Association between psoriasis and obsessive-compulsive disorder: a case-control study in the All of Us research program. Archives Of Dermatological Research 2024, 316: 280. PMID: 38796663, DOI: 10.1007/s00403-024-03112-y.
- Correction to: Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial ProgramKing B, Soung J, Tziotzios C, Rudnicka L, Joly P, Gooderham M, Sinclair R, Mesinkovska N, Paul C, Gong Y, Anway S, Tran H, Wolk R, Zwillich S, Lejeune A. Correction to: Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program. American Journal Of Clinical Dermatology 2024, 25: 689-689. PMID: 38789821, PMCID: PMC11193833, DOI: 10.1007/s40257-024-00864-1.
- Barriers to care and health-related quality of life among US adults with several common chronic inflammatory skin diseases: a cross-sectional analysis of the NIH All of Us Research ProgramNock M, Barbieri J, Cohen J. Barriers to care and health-related quality of life among US adults with several common chronic inflammatory skin diseases: a cross-sectional analysis of the NIH All of Us Research Program. Archives Of Dermatological Research 2024, 316: 201. PMID: 38775812, DOI: 10.1007/s00403-024-02954-w.
- Efficacy of laser hair removal in hidradenitis suppurativa: A systematic review and meta‐analysisShipman W, Williams M, Suozzi K, Eisenstein A, Dover J. Efficacy of laser hair removal in hidradenitis suppurativa: A systematic review and meta‐analysis. Lasers In Surgery And Medicine 2024, 56: 425-436. PMID: 38769894, DOI: 10.1002/lsm.23796.
- The Use of Biologic Agents for the Treatment of Cutaneous Immune-Related Adverse Events from Immune Checkpoint Inhibitors: A Review of Reported CasesPach J, Valido K, Belzer A, Leventhal J. The Use of Biologic Agents for the Treatment of Cutaneous Immune-Related Adverse Events from Immune Checkpoint Inhibitors: A Review of Reported Cases. American Journal Of Clinical Dermatology 2024, 25: 595-607. PMID: 38767827, DOI: 10.1007/s40257-024-00866-z.
- Topical Clindamycin in the Management of Acne Vulgaris: Current Perspectives and Recent Therapeutic Advances.Del Rosso J, Bunick C, Kircik L, Bhatia N. Topical Clindamycin in the Management of Acne Vulgaris: Current Perspectives and Recent Therapeutic Advances. Journal Of Drugs In Dermatology 2024, 23: 438-445. PMID: 38834223, DOI: 10.36849/jdd.8318.
- Successful treatment of pityriasis rubra pilaris with brodalumab after nonresponse to IL-17A inhibition: A role for the innate cytokine IL-17CValido K, Murphy M, Leventhal J, Damsky W. Successful treatment of pityriasis rubra pilaris with brodalumab after nonresponse to IL-17A inhibition: A role for the innate cytokine IL-17C. JAAD Case Reports 2024, 48: 85-87. PMID: 38783931, PMCID: PMC11111584, DOI: 10.1016/j.jdcr.2024.04.010.