Georges El Fakhri, PhD, DABR

2026

• Impact of depth-of-interaction and spatially-variant point-spread-function model on the performance of ultra-high resolution brain PET

  Zeng T, Najmaoui Y, Zhang J, Volpi T, Fontaine K, Chemli Y, Hu Y, Gallezot JD, Sun C, Lu Y, El Fakhri G, Carson RE, Marin T. Impact of depth-of-interaction and spatially-variant point-spread-function model on the performance of ultra-high resolution brain PET. Physics In Medicine & Biology 2026 DOI: 10.1088/1361-6560/aeafa5.

  Peer-Reviewed Original Research

• Deep learning enables quantitative kinetic modeling from low-dose dynamic [$$^{18}$$F]-MK6240 Tau PET

  Jang SI, Najmaoui Y, Chemli Y, Vafay Eslahi S, Guehl N, Dhaynaut M, El Fakhri G, Ma C, Ouyang J, Marin T. Deep learning enables quantitative kinetic modeling from low-dose dynamic [$$^{18}$$F]-MK6240 Tau PET. Scientific Reports 2026 DOI: 10.1038/s41598-026-69751-5.

  Peer-Reviewed Original Research

• Mid-life candidate vascular plasma biomarkers are associated with MRI markers of vascular brain injury and amyloid- and tau-PET in cognitively healthy adults.

  Mulligan M, Wang R, Yang Q, Beiser A, Maillard P, Satizabal C, Ghosh S, Tanner J, Johnson K, DeCarli C, Tracy R, Levy D, Benjamin E, El Fakhri G, Vasan R, Seshadri S, McGrath E. Mid-life candidate vascular plasma biomarkers are associated with MRI markers of vascular brain injury and amyloid- and tau-PET in cognitively healthy adults. Journal Of Alzheimer’s Disease 2026, 13872877261480733. PMID: 42669799, DOI: 10.1177/13872877261480733.

  Peer-Reviewed Original Research

• Integrated Investigation of Sex Differences in the Human Nociceptin/Orphanin FQ Receptor System: Postmortem Analyses and In Vivo [11C]NOP-1A Positron Emission Tomography Imaging

  Dhaynaut M, Morakabati N, Morris K, Matuskey D, Guehl N, Himes M, El Fakhri G, Narendran R, Berretta S, Normandin M, Pizzagalli D. Integrated Investigation of Sex Differences in the Human Nociceptin/Orphanin FQ Receptor System: Postmortem Analyses and In Vivo [11C]NOP-1A Positron Emission Tomography Imaging. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2026 PMID: 42648488, DOI: 10.1016/j.bpsc.2026.08.004.

  Peer-Reviewed Original Research

• Open-Geometry PET: quantifying the trade-off between time-of-flight resolution and angular coverage

  Razdevšek G, Dolenec R, Orehar M, Fakhri G, Majewski S, Pestotnik R. Open-Geometry PET: quantifying the trade-off between time-of-flight resolution and angular coverage. Physics In Medicine And Biology 2026, 71: 155031. PMID: 42341822, DOI: 10.1088/1361-6560/ae8217.

  Peer-Reviewed Original Research

  MeSH Keywords

• Neuromodulation with stereotactic radiosurgery to the nucleus accumbens in a rodent model of opioid use disorder

  MacDonagh A, Landry J, Rust P, Bussiere M, Dhaynaut M, Paronis C, Zhu X, Cotten J, Park H, Normandin M, Fakhri G, Shih H. Neuromodulation with stereotactic radiosurgery to the nucleus accumbens in a rodent model of opioid use disorder. Scientific Reports 2026 DOI: 10.1038/s41598-026-62216-9.

  Peer-Reviewed Original Research

• Power Battery Detection

  Zhao X, Cao P, Yu C, Feng Z, Zhang L, Liu H, Zuo J, Pang Y, Ouyang J, Lin W, El Fakhri G, Lu H, Liu X. Power Battery Detection. International Journal Of Computer Vision 2026, 134: 356. DOI: 10.1007/s11263-026-02919-8.

  Peer-Reviewed Original Research

• Influence of an AQP4 haplotype and sleep duration on early Alzheimer's disease

  Palatsides E, Yiallourou S, Himali D, Cavuoto M, Baril A, Yang Q, Peloso G, Ryan J, Fakhri G, Ghosh S, Thibault E, DeCarli C, Johnson K, Beiser A, Seshadri S, Himali J, Pase M. Influence of an AQP4 haplotype and sleep duration on early Alzheimer's disease. Alzheimer's & Dementia 2026, 22: e71540. PMID: 42222915, PMCID: PMC13239115, DOI: 10.1002/alz.71540.

  Peer-Reviewed Original Research

  Citations

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  MeSH Keywords

• Scan-wise generalized PET denoising with contrastive adversarial learning

  Liu X, Marin T, Eslahi S, Tiss A, Chemli Y, Najmaoui Y, Jang S, Fakhri G, Ouyang J. Scan-wise generalized PET denoising with contrastive adversarial learning. Physics In Medicine And Biology 2026, 71: 10.1088/1361-6560/ae7231. PMID: 42173146, PMCID: PMC13312193, DOI: 10.1088/1361-6560/ae7231.

  Peer-Reviewed Original Research

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  MeSH Keywords

• Direct Cardiac T1 Mapping with Subspace Modeling and Free-breathing Data Acquisition

  Marin T, Han P, Szezurek D, Zhuo Y, Mounime I, Djebra Y, Lee W, Fakhri G, Ma C. Direct Cardiac T1 Mapping with Subspace Modeling and Free-breathing Data Acquisition. IEEE Transactions On Biomedical Engineering 2026, PP: 1-10. PMID: 42184172, PMCID: PMC13249525, DOI: 10.1109/tbme.2026.3696845.

  Peer-Reviewed Original Research