Alterations of Fas-pathway genes associated with nodal metastasis innon-small cell lung cancer
Shin M, Kim H, Lee S, Lee J, Song Y, Kim Y, Park W, Kim S, Lee S, Park J, Lee J, Xiao W, Jo K, Wang Y, Lee K, Park Y, Kim S, Lee J, Yoo N. Alterations of Fas-pathway genes associated with nodal metastasis innon-small cell lung cancer. Oncogene 2002, 21: 4129-4136. PMID: 12037669, DOI: 10.1038/sj.onc.1205527.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAllelesApoptosisBase SequenceCarcinoma, Non-Small-Cell LungCarrier ProteinsCaspase 10Caspase 8Caspase 9CaspasesDNA Primersfas ReceptorFas-Associated Death Domain ProteinHumansLoss of HeterozygosityLung NeoplasmsLymphatic MetastasisMutagenesis, Site-DirectedConceptsFas-mediated apoptosisPathways of Fas-mediated apoptosisNon-small cell lung cancerResistance to Fas-mediated apoptosisTumor-derived mutantsProximal pathwayCancer cell deathApoptosis inductionWild typeInactivating mutationsTransfection studiesCell deathMetastasis of non-small cell lung cancerSomatic mutationsGenesCell lung cancerMutationsRegional lymph nodesApoptosisCancer cellsCancer metastasisMetastasis lesionsPrimary lesionLymph nodesLung cancer
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