2017
Role of Intrinsic (Graft) Versus Extrinsic (Host) Factors in the Growth of Transplanted Organs Following Allogeneic and Xenogeneic Transplantation
Tanabe T, Watanabe H, Shah J, Sahara H, Shimizu A, Nomura S, Asfour A, Danton M, Boyd L, Meyers A, Ekanayake-Alper D, Sachs D, Yamada K. Role of Intrinsic (Graft) Versus Extrinsic (Host) Factors in the Growth of Transplanted Organs Following Allogeneic and Xenogeneic Transplantation. American Journal Of Transplantation 2017, 17: 1778-1790. PMID: 28117931, PMCID: PMC5489354, DOI: 10.1111/ajt.14210.Peer-Reviewed Original ResearchConceptsIncreased serum creatinineDeterioration of organ functionRecipient body weightEvidence of rejectionLife Support OrganizationMiniature swineEarly growthLung allograftsSerum creatininePig graftsOrgan dysfunctionGraft volumeCortical ischemiaOrgan transplantationBody weightBaboon recipientsSwine kidneyXenograft kidneysXenogeneic transplantationTransplantationOrgan functionDonor organsKidneyTransplanted organSwine
2007
Vascularized composite islet-kidney transplantation in a miniature swine model
Vallabhajosyula P, Griesemer A, Yamada K, Sachs DH. Vascularized composite islet-kidney transplantation in a miniature swine model. Cell Biochemistry And Biophysics 2007, 48: 201-207. PMID: 17709890, DOI: 10.1007/s12013-007-0027-4.Peer-Reviewed Original ResearchConceptsThymic tissueIslet equivalentsEnd-stage diabetic nephropathyType I diabetic patientsAllogeneic thymic tissueRecipient body weightLong-term toleranceLong-term survivalMiniature swine modelKidney allograftsMHC barriersDiabetic nephropathyAllogeneic isletsAllogeneic transplantationDiabetic hyperglycemiaDiabetic patientsThymic componentsTreatment regimensPortal veinRenal capsuleOrgan transplantsAutologous isletsMiniature swineTransplantationBody weight
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