2018
Selective and synergistic cobalt(iii)-catalysed three-component C–H bond addition to dienes and aldehydes
Boerth JA, Maity S, Williams SK, Mercado BQ, Ellman JA. Selective and synergistic cobalt(iii)-catalysed three-component C–H bond addition to dienes and aldehydes. Nature Catalysis 2018, 1: 673-679. PMID: 30221249, PMCID: PMC6136669, DOI: 10.1038/s41929-018-0123-4.Peer-Reviewed Original ResearchH bond additionBond additionThree-component CCoupling partnersX-ray structural characterizationCarbon-carbon σ-bondsComplex molecular scaffoldsKinetic isotope studiesSynergistic reactivityDrug synthesisWestern fragmentsΣ-bondConvergent synthesisSimple precursorsStereochemical informationLasalocid A.New stereocentresMolecular scaffoldsRapid synthesisNatural productsStructural characterizationHigh regioRelevant moleculesDifferent coupling partnersAldehydes
2006
The Total Synthesis of Tubulysin D
Peltier HM, McMahon JP, Patterson AW, Ellman JA. The Total Synthesis of Tubulysin D. Journal Of The American Chemical Society 2006, 128: 16018-16019. PMID: 17165738, DOI: 10.1021/ja067177z.Peer-Reviewed Original Research
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