Diminished brain 5-HT transporter binding in major depression: a positron emission tomography study with [11C]DASB
Selvaraj S, Venkatesha Murthy N, Bhagwagar Z, Bose SK, Hinz R, Grasby PM, Cowen PJ. Diminished brain 5-HT transporter binding in major depression: a positron emission tomography study with [11C]DASB. Psychopharmacology 2009, 213: 555-562. PMID: 19756523, DOI: 10.1007/s00213-009-1660-y.Peer-Reviewed Original ResearchConceptsPositron emission tomography studyEmission tomography studiesDepressed patientsHealthy controlsMajor depressionMedication-free depressed patientsPoor long-term prognosisPrevious positron emission tomography (PET) studiesTomography studyLong-term prognosisAnterior cingulate cortexPositron emission tomographyBrain stemMean durationSerotonin neurotransmissionAcute depressionFrontal cortexPatientsCingulate cortexState markerBrain regionsEmission tomographyConclusionsThese resultsBrainDepression
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