2022
Neonatal outcomes by delivery indication after administration of antenatal late preterm corticosteroids
Deshmukh U, Lundsberg L, Pettker C, Rouse D, Reddy U. Neonatal outcomes by delivery indication after administration of antenatal late preterm corticosteroids. AJOG Global Reports 2022, 2: 100097. PMID: 36536839, PMCID: PMC9758401, DOI: 10.1016/j.xagr.2022.100097.Peer-Reviewed Original ResearchPreterm prelabor ruptureLate preterm deliveryPreterm delivery groupLate preterm periodNeonatal respiratory complicationsPreterm labor groupPreterm deliverySpontaneous preterm laborPreterm laborPrelabor rupturePrimary outcomeDelivery indicationsDelivery groupAntenatal corticosteroidsNeonatal complicationsPlacebo groupRespiratory complicationsPreterm periodLower oddsAntenatal Late Preterm Steroids trialNewborn intensive care unit admissionIntensive care unit admissionMultivariable logistic regression modelLate preterm infantsNeonatal respiratory outcomes
2021
Management of Cerclage in Patients With Preterm Prelabor Rupture of Membranes
Wu J, Denoble AE, Kuller JA, Dotters-Katz SK. Management of Cerclage in Patients With Preterm Prelabor Rupture of Membranes. Obstetrical & Gynecological Survey 2021, 76: 681-691. PMID: 34854925, DOI: 10.1097/ogx.0000000000000957.Peer-Reviewed Original ResearchConceptsMaternal infectious morbidityPreterm prelabor ruptureCerclage removalCervical cerclageInfectious morbidityNeonatal outcomesPrelabor ruptureNeonatal morbidity outcomesRetention of cerclageSetting of PPROMTime of PPROMTime of diagnosisCerclage placementCerclage retentionLatency antibioticsNeonatal complicationsCorticosteroid administrationMaternal morbidityPreterm laborNeonatal sepsisMorbidity outcomesNeonatal mortalityRetrospective natureDefinitive benefitPPROMOutcomes in Twins Compared With Singletons Subsequent to Preterm Prelabor Rupture of Membranes
Bartal M, Ugwu LG, Grobman WA, Bailit JL, Reddy UM, Wapner RJ, Varner MW, Thorp JM, Caritis SN, Prasad M, Tita ATN, Saade GR, Rouse DJ. Outcomes in Twins Compared With Singletons Subsequent to Preterm Prelabor Rupture of Membranes. Obstetrics And Gynecology 2021, 138: 725-731. PMID: 34619719, PMCID: PMC8542618, DOI: 10.1097/aog.0000000000004561.Peer-Reviewed Original ResearchMeSH KeywordsAdultChorioamnionitisCohort StudiesEndometritisEnterocolitis, NecrotizingFemaleFetal Membranes, Premature RuptureGestational AgeHumansInfant, NewbornInfant, PrematureOutcome Assessment, Health CarePerinatal MortalityPregnancyPregnancy OutcomePregnancy, TwinPremature BirthSepsisVenous ThromboembolismWound InfectionYoung AdultConceptsComposite maternal morbidityPreterm prelabor ruptureWeeks of gestationNeonatal morbidityPreterm PROMSingleton gestationsMaternal morbidityPrelabor ruptureTwin gestationsOdds ratioComposite major neonatal morbidityComposite neonatal morbidityMajor neonatal morbidityMedian gestational ageMedian latency periodMajor fetal anomaliesAdjusted odds ratioCoprimary outcomesObstetric cohortNeonatal outcomesTwin neonatesGestational agePotential confoundersFetal anomaliesMorbidityAntibiotics for Preterm Premature Rupture of Membranes
Kohari K, Pettker C. Antibiotics for Preterm Premature Rupture of Membranes. 2021, 43-47. DOI: 10.1093/med/9780190947088.003.0008.Peer-Reviewed Original ResearchNeonatal outcomesProlongation of pregnancyPreterm premature rupturePreterm prelabor ruptureBroad-spectrum antibioticsLength of pregnancyDays of gestationNeonatal complicationsPrelabor rupturePremature birthPremature ruptureSpectrum antibioticsPPROMPregnancyAntibioticsRisk reductionOutcomesMembrane ruptureWeeksRuptureOne-halfComplicationsPatientsGestationEtiology
2018
Tenascin-X in amniotic fluid and reproductive tissues of pregnancies complicated by infection and preterm prelabor rupture of membranes†
Rood KM, Buhimschi CS, Zhao G, Oliver EA, Summerfield T, Bahtiyar MO, Buhimschi IA. Tenascin-X in amniotic fluid and reproductive tissues of pregnancies complicated by infection and preterm prelabor rupture of membranes†. Biology Of Reproduction 2018, 100: 773-782. PMID: 30277495, PMCID: PMC6437262, DOI: 10.1093/biolre/ioy216.Peer-Reviewed Original ResearchConceptsIntra-amniotic infection/inflammationPreterm prelabor ruptureFetal membranesAmniotic fluidTNX expressionPrelabor ruptureInfection/inflammationLung maturity testingMembrane statusSpontaneous PPROMPregnancy complicationsNormal outcomeTherapeutic targetGenetic karyotypingReproductive tissuesPPROMMRNA expressionMaturity testingPregnancyWestern blottingMRNA levelsQRT-PCRExtracellular matrix proteinsCervixInflammation
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