2025
Using vascular biomarkers to assess heart failure event risk in hospitalized patients with and without AKI
Shi A, Andrawis A, Biswas A, Wilson F, Obeid W, Philbrook H, Go A, Ikizler T, Siew E, Chinchilli V, Hsu C, Garg A, Reeves W, Prince D, Bhatraju P, Coca S, Liu K, Kimmel P, Kaufman J, Wurfel M, Himmelfarb J, Parikh C, Mansour S. Using vascular biomarkers to assess heart failure event risk in hospitalized patients with and without AKI. BMC Nephrology 2025, 26: 271. PMID: 40457292, PMCID: PMC12131712, DOI: 10.1186/s12882-025-04169-1.Peer-Reviewed Original ResearchConceptsArea under the curveRisk of HF eventsHeart failureHF eventsHospitalized patientsPrediction of HFVascular biomarkersClinical modelHigher risk of HF eventsPrediction of HF eventsLevels of injury markersRates of heart failureDormant phenotypeAssociated with higher riskCox regression analysisHeart failure eventsCardiovascular disease risk factorsPost-hospitalizationDisease risk factorsSerum creatinineAKI patientsStratify patientsInjury markersLung diseaseClinical centers
2015
Assessing mitral regurgitation in the prediction of clinical outcome after cardiac resynchronization therapy
Upadhyay G, Chatterjee N, Kandala J, Friedman D, Park M, Tabtabai S, Hung J, Singh J. Assessing mitral regurgitation in the prediction of clinical outcome after cardiac resynchronization therapy. Heart Rhythm 2015, 12: 1201-1208. PMID: 25708879, DOI: 10.1016/j.hrthm.2015.02.022.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyDegree of baseline MRMitral regurgitationBaseline MRMR improvementHF hospitalizationClinical outcomesSurface QRSHeart failureAssociated with lower HF hospitalizationsCohort study of patientsImproved ventricular geometryFollow-up echocardiographyPrediction of clinical outcomeReducing mitral regurgitationStudy of patientsAll-Cause MortalityPrediction of HFWorsening MRMR severityMedian ageIschemic cardiomyopathyResynchronization therapyImproved survivalMR reduction
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