2020
Antibody reactivity with new antigens revealed in multi‐transgenic triple knockout pigs may cause early loss of pig kidneys in baboons
Ariyoshi Y, Takeuchi K, Pomposelli T, Ekanayake‐Alper D, Shimizu A, Boyd L, Estime E, Ohta M, Asfour A, Arn J, Ayares D, Lorber M, Sykes M, Sachs D, Yamada K. Antibody reactivity with new antigens revealed in multi‐transgenic triple knockout pigs may cause early loss of pig kidneys in baboons. Xenotransplantation 2020, 28: e12642. PMID: 32909301, PMCID: PMC8957702, DOI: 10.1111/xen.12642.Peer-Reviewed Original ResearchConceptsPeripheral blood mononuclear cellsCytidine monophospho-N-acetylneuraminic acid hydroxylaseEndothelial protein C receptorTransgenic pigsMulti-transgenesPigsPre-screening assayPig kidneyGene editing technologyPig-to-baboonRenal functionKO pigsEditing technologyVascularized thymic graftsBaboon seraKnockout pigsStable renal functionGalT-KOHuman thrombomodulinMaintained renal functionBlood mononuclear cellsAcute xenograft rejectionProtein C receptorGenetic manipulationNatural antibodies
1994
Kinetic heterogeneity of phosphoenzyme of Na,K-ATPase modeled by unmixed lipid phases. Competence of the phosphointermediate.
Klodos I, Post R, Forbush B. Kinetic heterogeneity of phosphoenzyme of Na,K-ATPase modeled by unmixed lipid phases. Competence of the phosphointermediate. Journal Of Biological Chemistry 1994, 269: 1734-1743. PMID: 8294422, DOI: 10.1016/s0021-9258(17)42089-8.Peer-Reviewed Original Research
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