2025
Safety and effectiveness of fecal microbiota, live-jslm (REBYOTA®) administered by colonoscopy for prevention of recurrent Clostridioides difficile infection: 8-week results from CDI-SCOPE, a single-arm, phase IIIb trial
Khanna S, Yoho D, Van Handel D, Clark B, Awad T, Guthmueller B, Armandi D, Knapple W, Safdar N, Baggott B, Simon K, Feuerstadt P. Safety and effectiveness of fecal microbiota, live-jslm (REBYOTA®) administered by colonoscopy for prevention of recurrent Clostridioides difficile infection: 8-week results from CDI-SCOPE, a single-arm, phase IIIb trial. Therapeutic Advances In Gastroenterology 2025, 18: 17562848251339697. PMID: 40321366, PMCID: PMC12049624, DOI: 10.1177/17562848251339697.Peer-Reviewed Original ResearchTreatment-emergent adverse eventsPhase IIIb trialAntibiotic treatmentPrevention of recurrent CDINo treatment emergent adverse eventsTreatment successRecurrent Clostridioides difficile infectionClostridioides difficile</i> infectionIntensive care unit admissionParticipation benefitsPrevent CDI recurrenceClostridioides difficile infectionRoute of administrationPhysicians' perceptionsPreventing rCDICDI recurrenceTreatment failureEligible adultsSecondary endpointsFecal microbiotaEffects of fecal microbiotaUnit admissionDifficile infectionAdverse eventsPhysician experience
2024
A machine learning framework to adjust for learning effects in medical device safety evaluation
Koola J, Ramesh K, Mao J, Ahn M, Davis S, Govindarajulu U, Perkins A, Westerman D, Ssemaganda H, Speroff T, Ohno-Machado L, Ramsay C, Sedrakyan A, Resnic F, Matheny M. A machine learning framework to adjust for learning effects in medical device safety evaluation. Journal Of The American Medical Informatics Association 2024, 32: 206-217. PMID: 39471493, PMCID: PMC11648715, DOI: 10.1093/jamia/ocae273.Peer-Reviewed Original ResearchMachine Learning FrameworkSynthetic datasetsLearning frameworkMachine learningCapacity of MLLearning effectFeature correlationDepartment of Veterans AffairsSynthetic dataData generationAbsence of learning effectsTraditional statistical methodsML methodsSuperior performanceDatasetSafety signal detectionSignal detectionDevice signalsVeterans AffairsTime-varying covariatesLearningMachinePhysician experienceLimitations of traditional statistical methodsMedical device post-market surveillanceEducational and personal impacts of the COVID-19 pandemic on emergency medicine resident physicians: a qualitative study
Fults E, Gerwin J, Boyce M, Joseph M, Wong A, Evans L. Educational and personal impacts of the COVID-19 pandemic on emergency medicine resident physicians: a qualitative study. BMC Medical Education 2024, 24: 1055. PMID: 39334215, PMCID: PMC11429862, DOI: 10.1186/s12909-024-05972-4.Peer-Reviewed Original ResearchConceptsEmergency medicine resident physiciansResident physiciansQualitative studyEmergency departmentResident physicians' experiencesEmergency medicine facultyCOVID-19 pandemicResident physician trainingResidency program leadershipSocial support systemsBackgroundThe COVID-19 pandemicData saturationPhysician trainingCode teamFrontline physiciansPractice styleUrban academic institutionProgram leadershipPhysician experienceMedicine facultyResident experiencePersonal impactPhysiciansMoral injuryResident preparationConsiderations for instituting pediatric pulmonary embolism response teams: A tool kit
Rajpurkar M, Rosovsky R, Williams S, Chan A, van Ommen C, Faustino E, White M, Parikh M, Sirachainan N, Biss T, Goldenberg N. Considerations for instituting pediatric pulmonary embolism response teams: A tool kit. Thrombosis Research 2024, 236: 97-107. PMID: 38417301, DOI: 10.1016/j.thromres.2024.02.019.Peer-Reviewed Original ResearchPulmonary Embolism Response TeamPediatric pulmonary embolismPediatric PETime to diagnosisIndividual physician's experiencePulmonary embolismDefinitive managementPE patientsResponse teamCritical care pathwayEpidemiological featuresCare pathwaysPhysician experiencePractice guidelinesPE outcomesDiagnosisCritical pathways
2019
Physician Experience and Risk of Rituximab Discontinuation in Older Adults With Non-Hodgkin's Lymphoma.
Huntington SF, Hoag JR, Wang R, Zeidan AM, Giri S, Gore SD, Ma X, Gross CP, Davidoff AJ. Physician Experience and Risk of Rituximab Discontinuation in Older Adults With Non-Hodgkin's Lymphoma. Journal Of The National Comprehensive Cancer Network 2019, 17: 1194-1202. PMID: 31590152, DOI: 10.6004/jnccn.2019.7314.Peer-Reviewed Original ResearchConceptsRituximab discontinuationRituximab initiationHodgkin's lymphomaRelative riskPhysician experienceHigh-quality cancer careOlder adultsInitiation of rituximabEarly treatment discontinuationInfusion-related reactionsPopulation-based studySEER-Medicare dataNon-Hodgkin lymphomaModified Poisson regressionCancer treatment outcomesEarly discontinuationTreatment discontinuationAnticancer immunotherapyPhysician volumeCancer careImproved outcomesOncologists' experiencesTreatment outcomesDiscontinuationRituximab
2018
“To Err Is Human” but Disclosure Must be Taught
Crimmins AC, Wong AH, Bonz JW, Tsyrulnik A, Jubanyik K, Dziura JD, Dodge KL, Evans LV. “To Err Is Human” but Disclosure Must be Taught. Simulation In Healthcare The Journal Of The Society For Simulation In Healthcare 2018, 13: 107-116. PMID: 29346222, DOI: 10.1097/sih.0000000000000273.Peer-Reviewed Original ResearchConceptsError disclosurePractice guidelinesEmergency medicineMedical studentsMedical error disclosurePatient-centered careSenior EM residentsAttending EM physiciansLevels of clinical experienceIncreasing physician experienceProspective cohort studyLevel of trainingImmersive simulation scenariosEM physiciansEM residentsHealthcare providersSafe practice guidelinesPhysician experienceAttending physiciansAdverse eventsCohort studySuboptimal adherenceTotal scorePromote safetyProviders
2016
Physician Experience and Attitudes Toward Addressing the Cost of Cancer Care.
Altomare I, Irwin B, Zafar S, Houck K, Maloney B, Greenup R, Peppercorn J, Altomare I, Irwin B, Zafar S, Houck K, Maloney B, Greenup R, Peppercorn J. Physician Experience and Attitudes Toward Addressing the Cost of Cancer Care. JCO Oncology Practice 2016, 12: e281-8, 247-8. PMID: 26883407, PMCID: PMC4960469, DOI: 10.1200/jop.2015.007401.Peer-Reviewed Original ResearchConceptsCancer careCost discussionsRespondents' practice settingCost of careCancer doctorsPhysician experiencePatientsPocket costsPractice settingsASCO membersOptimal timingMajority of respondentsSocietal costsLack of consensusPrivate practiceSubstantial proportionCareElectronic surveyClinicPhysiciansPractice managementDoctorsDiscussion of costTotalLack of resources
2009
Race/Ethnicity and Workplace Discrimination: Results of a National Survey of Physicians
Nunez-Smith M, Pilgrim N, Wynia M, Desai MM, Jones BA, Bright C, Krumholz HM, Bradley EH. Race/Ethnicity and Workplace Discrimination: Results of a National Survey of Physicians. Journal Of General Internal Medicine 2009, 24: 1198. PMID: 19727966, PMCID: PMC2771235, DOI: 10.1007/s11606-009-1103-9.Peer-Reviewed Original Research
1999
Physician Experiences With, and Ratings of, Managed Care Organizations in Massachusetts
Williams T, Zaslavsky A, Cleary P. Physician Experiences With, and Ratings of, Managed Care Organizations in Massachusetts. Medical Care 1999, 37: 589-600. PMID: 10386571, DOI: 10.1097/00005650-199906000-00008.Peer-Reviewed Original ResearchMeSH KeywordsAttitude of Health PersonnelEducation, Medical, ContinuingEvaluation Studies as TopicFactor Analysis, StatisticalFemaleHealth Knowledge, Attitudes, PracticeHealth Services ResearchHumansJob SatisfactionMaleManaged Care ProgramsMassachusettsPhysician Incentive PlansPhysiciansProfessional PracticeQuality of Health CareSurveys and Questionnaires
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