A novel role for DNA photolyase: binding to DNA damaged by drugs is associated with enhanced cytotoxicity in Saccharomyces cerevisiae.
Fox M, Feldman B, Chu G. A novel role for DNA photolyase: binding to DNA damaged by drugs is associated with enhanced cytotoxicity in Saccharomyces cerevisiae. Molecular And Cellular Biology 1994, 14: 8071-8077. PMID: 7969145, PMCID: PMC359345, DOI: 10.1128/mcb.14.12.8071.Peer-Reviewed Original ResearchMeSH Keywords4-Nitroquinoline-1-oxideCisplatinDeoxyribodipyrimidine Photo-LyaseDNA DamageDNA, FungalDNA-Binding ProteinsDose-Response Relationship, DrugEndodeoxyribonucleasesFungal ProteinsMechlorethamineMethylnitronitrosoguanidinePyrimidine DimersSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsConceptsBinding to DNADNA photolyaseYeast Saccharomyces cerevisiaeGenes increased sensitivityAlkylating agent N-methyl-N'-nitro-N-nitrosoguanidineInterfere with cell survivalRepair cyclobutane pyrimidine dimersSaccharomyces cerevisiaeAssociated with resistanceCyclobutane pyrimidine dimersNucleotide excision repair systemN-methyl-N'-nitro-N-nitrosoguanidineExcision repair systemCell survivalDNAPhotolyasePyrimidine dimersAIDS survivalAnticancer drug cis-diamminedichloroplatinumRepair systemCis-DDPYeastMutantsNucleotideMutationsA Novel Role for DNA Photolyase: Binding to DNA Damaged by Drugs Is Associated with Enhanced Cytotoxicity in Saccharomyces cerevisiae
Fox M, Feldman B, Chu G. A Novel Role for DNA Photolyase: Binding to DNA Damaged by Drugs Is Associated with Enhanced Cytotoxicity in Saccharomyces cerevisiae. Molecular And Cellular Biology 1994, 14: 8071-8077. DOI: 10.1128/mcb.14.12.8071-8077.1994.Peer-Reviewed Original ResearchBinding to DNADNA photolyaseYeast Saccharomyces cerevisiaeGenes increased sensitivityAlkylating agent N-methyl-N'-nitro-N-nitrosoguanidineInterfere with cell survivalRepair cyclobutane pyrimidine dimersSaccharomyces cerevisiaeAssociated with resistanceCyclobutane pyrimidine dimersNucleotide excision repair systemN-methyl-N'-nitro-N-nitrosoguanidineExcision repair systemCell survivalDNAPhotolyaseNovel rolePyrimidine dimersAIDS survivalAnticancer drug cis-diamminedichloroplatinumRepair systemAssociated with enhanced cytotoxicityCis-DDPYeastMutants
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