2022
Prevention of alcohol withdrawal syndrome in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document
Seshadri A, Appelbaum R, Carmichael S, Farrell M, Filiberto D, Jawa R, Kodadek L, Mandell S, Miles M, Paul J, Robinson B, Michetti C. Prevention of alcohol withdrawal syndrome in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document. Trauma Surgery & Acute Care Open 2022, 7: e001010. PMID: 36425749, PMCID: PMC9680182, DOI: 10.1136/tsaco-2022-001010.Peer-Reviewed Original ResearchClinical consensus documentAlcohol withdrawal syndromeSurgical ICUAlcohol withdrawalWithdrawal syndromeConsensus documentSurgical intensive care unit patientsIntensive care unit patientsCare unit patientsChallenging clinical entityCritical Care CommitteeAmerican AssociationUnit patientsClinical entityProphylactic treatmentPharmacological methodsCare CommitteeScreening toolICUSurgerySyndromeWithdrawalAssociationPatientsTrauma
2015
Systemic Administration of the TRPV3 Ion Channel Agonist Carvacrol Induces Hypothermia in Conscious Rodents
Feketa V, Marrelli S. Systemic Administration of the TRPV3 Ion Channel Agonist Carvacrol Induces Hypothermia in Conscious Rodents. PLOS ONE 2015, 10: e0141994. PMID: 26528923, PMCID: PMC4631363, DOI: 10.1371/journal.pone.0141994.Peer-Reviewed Original ResearchConceptsHypothermic effectConscious patientsNovel pharmacological methodHigh intravenous dosesInduction of hypothermiaTherapeutic hypothermiaBlood pressureIntravenous dosesSuboptimal effectivenessConscious rodentsPromising new strategySystemic administrationIntravenous administrationCold-seeking behaviorPharmacological methodsSubstantial toxicityHypothermia inductionSafe dosesHypothermiaChannel activationPatientsCore temperatureMiceAdministrationDoses
2012
The role of inhibition in oscillatory wave dynamics in the cortex
Xiao Y, Huang X, Van Wert S, Barreto E, Wu J, Gluckman B, Schiff S. The role of inhibition in oscillatory wave dynamics in the cortex. European Journal Of Neuroscience 2012, 36: 2201-2212. PMID: 22805065, PMCID: PMC4410882, DOI: 10.1111/j.1460-9568.2012.08132.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBicucullineCarbacholEpilepsies, PartialGABA-A Receptor AgonistsGABA-A Receptor AntagonistsGABA-B Receptor AgonistsGABA-B Receptor AntagonistsMaleMembrane PotentialsModels, NeurologicalNeocortexNeural InhibitionPicrotoxinRatsRats, Sprague-DawleyReceptors, AMPAReceptors, GABA-AReceptors, GABA-BReceptors, N-Methyl-D-AspartateTheta RhythmConceptsGABAergic inhibitionNeocortical brain slicesVoltage-sensitive dye imagingSprague-Dawley ratsPresence of carbacholConcentration-dependent mannerGABAB antagonistGABAA receptorsBrain slicesTheta frequency oscillationsPharmacological methodsDye imagingCortical oscillationsRole of inhibitionBicucullineDisinhibitionGABAATheta oscillationsCortexBasic spatiotemporal patternsInhibitionNeural information processingCarbacholMental tasksAntagonist
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply