Newborn Brain Function and Early Emerging Callous-Unemotional Traits
Brady R, Donohue M, Waller R, Latham A, Ayala M, Smyser T, Warner B, Barch D, Luby J, Rogers C, Smyser C. Newborn Brain Function and Early Emerging Callous-Unemotional Traits. JAMA Psychiatry 2024, 81: 303-311. PMID: 38117491, PMCID: PMC10733851, DOI: 10.1001/jamapsychiatry.2023.4842.Peer-Reviewed Original ResearchConceptsCallous-unemotional traitsMedial prefrontal cortexChild externalizing symptomsCingulo-opercular networkFunctional connectivityExternalizing symptomsInventory of Callous-Unemotional TraitsChild callous-unemotional traitsBrain functionAssociated with lower empathyNovel intervention developmentPersistent conduct problemsExposure to socioeconomic disadvantageAt-risk childrenCallous-unemotionalNeurobiological underpinningsPrefrontal cortexLow empathyLow prosocialityNeural mechanismsBrain regionsConnectivity analysisDevelopment of novel treatmentsProsocialityLongitudinal cohort study
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