2025
O-123 Ultrafast versus conventional blastocyst warming: equivalent developmental outcomes following the extended in vitro culture of 221 embryos beyond the implantation stages
Venturas M, Ardestani G, Zamora M, Azpiroz F, Pujol A, Mataró D, Rodriguez-Aranda A, Lledó B, Nodar F, Miguel-Escalada I, Sakkas D, Popovic M. O-123 Ultrafast versus conventional blastocyst warming: equivalent developmental outcomes following the extended in vitro culture of 221 embryos beyond the implantation stages. Human Reproduction 2025, 40: deaf097.123. DOI: 10.1093/humrep/deaf097.123.Peer-Reviewed Original ResearchPGT-AMaternal ageChromosomal statusClinical outcomesClinical studiesInner cell mass qualityExtended in vitro culturePost-warming survival rateWarming protocolDevelopmental potentialConventional warmingEmbryo developmental potentialPGT-A resultsPreimplantation genetic testingInvestigate clinical outcomesProspective clinical studyImplantation assayFisher's exact testFactors present in vivoDevelopmental outcomesEuploid blastocystsSurviving blastocystsTrophectoderm qualityEuploid embryosBlastocyst biopsy
2020
A multicenter, prospective, blinded, nonselection study evaluating the predictive value of an aneuploid diagnosis using a targeted next-generation sequencing–based preimplantation genetic testing for aneuploidy assay and impact of biopsy
Tiegs AW, Tao X, Zhan Y, Whitehead C, Kim J, Hanson B, Osman E, Kim TJ, Patounakis G, Gutmann J, Castelbaum A, Seli E, Jalas C, Scott RT. A multicenter, prospective, blinded, nonselection study evaluating the predictive value of an aneuploid diagnosis using a targeted next-generation sequencing–based preimplantation genetic testing for aneuploidy assay and impact of biopsy. Fertility And Sterility 2020, 115: 627-637. PMID: 32863013, DOI: 10.1016/j.fertnstert.2020.07.052.Peer-Reviewed Original ResearchConceptsPreimplantation genetic testingSustained implantationPredictive valueGenetic testingClinical outcomesTrophectoderm biopsyAge-matched control groupImpact of biopsyPGT-A resultsAntral follicle countRecurrent pregnancy lossBody mass indexDetectable adverse impactAneuploid resultsSecondary outcomesFertilization cyclesFollicle countPrimary outcomeMass indexUsable blastocystsBlastocyst transferFertility centerPregnancy lossClinical error ratesStudy group
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