2018
A Review of Goal-Directed Cardiopulmonary Bypass Management in Pediatric Cardiac Surgery
Medikonda R, Ong CS, Wadia R, Goswami D, Schwartz J, Wolff L, Hibino N, Vricella L, Barodka V, Steppan J. A Review of Goal-Directed Cardiopulmonary Bypass Management in Pediatric Cardiac Surgery. World Journal For Pediatric And Congenital Heart Surgery 2018, 9: 565-572. PMID: 30157729, DOI: 10.1177/2150135118775964.Peer-Reviewed Original ResearchConceptsGoal-directed therapyVenous oxygen saturationPerfusion managementOxygen saturationCentral venous oxygen saturationGoal-directed perfusionVital clinical parametersEnd-organ perfusionPediatric cardiac surgeryCardiopulmonary bypass managementPatient's specific needsTransfusion ratePostoperative outcomesArterial pressureCardiac surgeryPerfusion flow rateClinical parametersPlatelet countPatient outcomesPostoperative monitoringCardiothoracic surgeryCoagulation stateBypass managementPerfusion pulsatilityPerfusion
1989
Determinants of glutathione efflux and biliary GSH/GSSG ratio in perfused rat liver
Ballatori N, Truong A, K. A, Boyer J. Determinants of glutathione efflux and biliary GSH/GSSG ratio in perfused rat liver. American Journal Of Physiology 1989, 256: g482-g490. PMID: 2564253, DOI: 10.1152/ajpgi.1989.256.3.g482.Peer-Reviewed Original ResearchConceptsGamma-glutamyl transferase activityO2 deliveryBiliary glutathioneHepatic effluxSinusoidal effluxKrebs-Ringer bicarbonate bufferGlutathione effluxRat liverEfflux of glutathioneGSH/GSSG ratioRed blood cellsPerfusion flow rateFluorocarbon emulsionsBile flowTissue GSHOxygen deliveryTransferase activityAT-125LiverBovine red blood cellsPerfusate compositionBlood cellsBileGSSG levelsGSSG ratio
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