2017
Shear Stress Induces Change in Extracellular Signal-Regulated Kinase 5 Levels with Sustained Activation under Disturbed and Continuous Laminar Flow
Shalaby SY, Chitragari G, Sumpio BJ, Sumpio BE. Shear Stress Induces Change in Extracellular Signal-Regulated Kinase 5 Levels with Sustained Activation under Disturbed and Continuous Laminar Flow. International Journal Of Angiology 2017, 26: 109-115. PMID: 28566937, PMCID: PMC5446257, DOI: 10.1055/s-0037-1599057.Peer-Reviewed Original ResearchExtracellular signal-regulated kinase 5Pathogenesis of atherosclerosisExposure of HUVECERK5 activationVascular dysfunctionPattern of activationFro flowVascular remodelingConfluent HUVECsHours of exposurePhospho-ERK5Endothelial integrityActivation of ERK5Kinase 5Sustained activationEnd of experimentationERK5 phosphorylationHUVECActivationHoursExposureTransient phosphorylationCell lysatesDisturbed flow conditionsParallel plate flow chamber
2013
Differences in dual-task performance and prefrontal cortex activation between younger and older adults
Ohsugi H, Ohgi S, Shigemori K, Schneider E. Differences in dual-task performance and prefrontal cortex activation between younger and older adults. BMC Neuroscience 2013, 14: 10. PMID: 23327197, PMCID: PMC3552708, DOI: 10.1186/1471-2202-14-10.Peer-Reviewed Original ResearchConceptsOxy-Hb valuesTMT-B scoresPFC activationAttentional functionsTask performanceBrain activationOlder adultsTask factorsExecutive/attentional functionsMixed ANOVADual-task challengesDual-task performanceHigh cognitive loadTest Part BPrefrontal cortex activityPrefrontal cortex activationTask performance accuracyPost-task periodDual-task activitiesTask-related changesPattern of activationTask-induced changesBaseline attentionExecutive functionCognitive load
2011
What's the story? The tale of reading fluency told at speed
Benjamin CF, Gaab N. What's the story? The tale of reading fluency told at speed. Human Brain Mapping 2011, 33: 2572-2585. PMID: 21954000, PMCID: PMC3499039, DOI: 10.1002/hbm.21384.Peer-Reviewed Original ResearchConceptsFluent readingSentence readingReading speedNovel fMRI taskReading-related regionsRight-handed adultsPattern of activationFMRI taskFusiform cortexReading conditionMore recent conceptualizationsSingle wordsFluent sentencesMiddle temporalRecent conceptualizationsReaders processDiscrete skillsFluencyBrain regionsInterest analysisRegion responseReadingTaskSentencesWords
2008
Retinocollicular Synapse Maturation and Plasticity Are Regulated by Correlated Retinal Waves
Shah RD, Crair MC. Retinocollicular Synapse Maturation and Plasticity Are Regulated by Correlated Retinal Waves. Journal Of Neuroscience 2008, 28: 292-303. PMID: 18171946, PMCID: PMC6671137, DOI: 10.1523/jneurosci.4276-07.2008.Peer-Reviewed Original ResearchMeSH KeywordsAge Factorsalpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidAnimalsAnimals, NewbornBehavior, AnimalDose-Response Relationship, RadiationElectric StimulationExcitatory Amino Acid AntagonistsIn Vitro TechniquesMiceMice, KnockoutN-MethylaspartateNeuronal PlasticityPatch-Clamp TechniquesQuinoxalinesReceptors, NicotinicRetinaSuperior ColliculiSynapsesSynaptic TransmissionVisual PathwaysConceptsFirst postnatal weekRetinal wavesPostnatal weekSynapse maturationAMPA/NMDA ratioRetinotopic map refinementSpontaneous retinal wavesNicotinic ACh receptorsSecond postnatal weekRetinocollicular synapsesSynapses decreasesPattern of activationNMDA ratioSynaptic strengtheningACh receptorsQuantal amplitudeRetinotopic map formationSuperior colliculusControl synapsesSynaptic changesCoincident activityPlasticity protocolsFirst weekBeta2 subunitWeeks
2006
Functional Neuroimaging Applications for Assessment and Rehabilitation Planning in Patients With Disorders of Consciousness
Giacino JT, Hirsch J, Schiff N, Laureys S. Functional Neuroimaging Applications for Assessment and Rehabilitation Planning in Patients With Disorders of Consciousness. Archives Of Physical Medicine And Rehabilitation 2006, 87: 67-76. PMID: 17140882, DOI: 10.1016/j.apmr.2006.07.272.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessHigher-order association corticesStudy of patientsRestoration of functionPrimary cortical areasFunctional magnetic resonanceFunctional neuroimaging techniquesFunctional neuroimaging protocolsPotential clinical applicationsPathophysiologic mechanismsPattern of activationPatient characterizationPositron emission tomography activation studyDifferential diagnosisPrognostic assessmentDisconnection syndromeCortical areasAssociation cortexLarge-scale cortical networksPatientsNeuroimaging protocolVegetative stateNeuroimaging techniquesConscious stateCortical networksLanguage lateralization and the role of the fusiform gyrus in semantic processing in young children
Balsamo LM, Xu B, Gaillard WD. Language lateralization and the role of the fusiform gyrus in semantic processing in young children. NeuroImage 2006, 31: 1306-1314. PMID: 16545581, DOI: 10.1016/j.neuroimage.2006.01.027.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBrain MappingCerebral CortexChildChild, PreschoolDecision MakingDominance, CerebralFemaleFrontal LobeHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMotor CortexNeuropsychological TestsOxygenPsychomotor PerformanceReaction TimeReadingSemanticsSpeech PerceptionConceptsSemantic processingFusiform gyrusEarly word recognition processesAuditory semantic processingWord recognition processesAdult language processingSemantic decision taskSemantic category decisionsLeft fusiform gyrusPrevious neuroimaging findingsLeft-lateralized patternYoung childrenPattern of activationLanguage comprehensionDecision taskCategory decisionsTask accuracyTask difficultyLanguage developmentLanguage lateralizationFMRI techniquesLanguage processingBrain regionsCortical regionsNeuroimaging findings
1995
Sex differences in the functional organization of the brain for language
Shaywitz B, Shaywltz S, Pugh K, Constable R, Skudlarski P, Fulbright R, Bronen R, Fletcher J, Shankweiler D, Katz L, Gore J. Sex differences in the functional organization of the brain for language. Nature 1995, 373: 607-609. PMID: 7854416, DOI: 10.1038/373607a0.Peer-Reviewed Original ResearchConceptsLeft inferior frontal gyrus regionsInferior frontal gyrus regionsRight inferior frontal gyrusSex differencesInferior frontal gyrusFunctional organizationPattern of activationRight-handed subjectsPhonological processingPhonological tasksSemantic tasksBrain activationFrontal gyrusLanguage functionNeural systemsGyrus regionsCerebral hemispheresTaskLanguageBrainGyrusOrganizationMalesProcessingActivation
1986
Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.
Pober JS, Gimbrone MA, Lapierre LA, Mendrick DL, Fiers W, Rothlein R, Springer TA. Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. The Journal Of Immunology 1986, 137: 1893-6. PMID: 3091693, DOI: 10.4049/jimmunol.137.6.1893.Peer-Reviewed Original ResearchConceptsTumor necrosis factorIFN-gammaHuman umbilical vein endothelialNecrosis factorIL-1Interleukin-1HUVE cellsImmune interferonIntercellular adhesion molecule-1Endothelial cellsDifferent immune mediatorsAdhesion molecule-1Murine monoclonal antibodiesHuman endothelial cellsImmune mediatorsPattern of activationActivation antigensAntigenic modulationB antigensDifferent lymphokinesMolecule-1Monoclonal antibodiesProgressive increaseInterferonAntigen
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