2025
Buprenorphine induces human fetal membrane sterile inflammation
Lynn T, Kelleher M, Georges H, McCauley E, Logan R, Yonkers K, Abrahams V. Buprenorphine induces human fetal membrane sterile inflammation. Journal Of Reproductive Immunology 2025, 168: 104445. PMID: 39914058, PMCID: PMC11890952, DOI: 10.1016/j.jri.2025.104445.Peer-Reviewed Original ResearchConceptsOpioid-use disorderPreterm birthToll-like receptor 4Prostaglandin E2Sterile inflammationRate of preterm birthAssociated with pregnancy complicationsInnate immune toll-like receptor 4Maternal-fetal interfaceNeutrophil chemokine IL-8Induce sterile inflammationM-opioid receptorCytokines IL-1bInflammatory cytokines IL-6Chemokine IL-8Cytokines IL-6Maternal morbidityPregnancy complicationsOpioid useOpioid-usersHuman FMInflammatory profileMembrane weakeningIL-1BPreterm
2024
Provider–patient relationships and trauma among pregnant patients with opioid‐use disorder
Doernberg M, Gilstad‐Hayden K, Yonkers K, Forray A. Provider–patient relationships and trauma among pregnant patients with opioid‐use disorder. American Journal On Addictions 2024, 33: 569-575. PMID: 38685767, DOI: 10.1111/ajad.13570.Peer-Reviewed Original ResearchProbable posttraumatic stress disorderOpioid-use disorderPosttraumatic stress disorderPregnant patientsAlliance ScaleProvider-patient relationshipStress disorderFifth editionPregnant participantsIntegration subscaleCommunication subscaleTrauma-informed practicesTreatment trialsWeeks of pregnancyDemographic variablesDisordersSubscalesVulnerable patient populationObstetric providersPrenatal carePatient populationSevere traumaPatientsScoresParticipants
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