Occasional cannabis use is associated with higher premorbid functioning and IQ in youth at clinical high-risk (CHR) for psychosis: Parallel findings to psychosis cohorts
Kennedy L, Ku B, Addington J, Amir C, Bearden C, Cannon T, Carrión R, Cornblatt B, Keshavan M, Perkins D, Mathalon D, Stone W, Walker E, Woods S, Cadenhead K. Occasional cannabis use is associated with higher premorbid functioning and IQ in youth at clinical high-risk (CHR) for psychosis: Parallel findings to psychosis cohorts. Schizophrenia Research 2024, 271: 319-331. PMID: 39084107, PMCID: PMC11955428, DOI: 10.1016/j.schres.2024.07.032.Peer-Reviewed Original ResearchClinical high riskCannabis use frequencyPremorbid functioningCannabis usePsychosis cohortSocial functioningCannabis usersAssociated with greater symptom severityAssociated with better neurocognitionNorth American Prodrome Longitudinal StudyClinical high-risk participantsClinical high-risk youthClinical high-risk populationsUse groupRates of cannabis useCannabis use groupsMeasures of IQCannabis use patternsGreater symptom severityHigher premorbid functioningFollow-up analysisPsychosis sampleHigher IQNeurocognitive domainsFirst-episodeEnlarged pituitary gland volume: a possible state rather than trait marker of psychotic disorders
Guimond S, Alftieh A, Devenyi G, Mike L, Chakravarty M, Shah J, Parker D, Sweeney J, Pearlson G, Clementz B, Tamminga C, Keshavan M. Enlarged pituitary gland volume: a possible state rather than trait marker of psychotic disorders. Psychological Medicine 2024, 54: 1835-1843. PMID: 38357733, PMCID: PMC11132920, DOI: 10.1017/s003329172300380x.Peer-Reviewed Original ResearchPituitary gland volumePsychotic disordersSymptom severityAntipsychotic doseIllness durationCognitive functionAssociated with greater symptom severitySignificant effect of diagnosisAssociated with symptom severityHigher antipsychotic dosePituitary volumeBipolar-Schizophrenia NetworkIntermediate Phenotypes consortiumStructural magnetic resonance imagingProgression of psychosisGreater symptom severityEffect of diagnosisLower cognitive functionMore severe symptomsSample of individualsTransdiagnostic sampleMAGeT Brain algorithmGland volumeTrait markerBetween-group differences
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply