Whole-brain white matter variation across childhood environments
Carozza S, Kletenik I, Astle D, Schwamm L, Dhand A. Whole-brain white matter variation across childhood environments. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2409985122. PMID: 40193606, PMCID: PMC12012481, DOI: 10.1073/pnas.2409985122.Peer-Reviewed Original ResearchConceptsAdolescent Brain Cognitive DevelopmentAssociated with later difficultiesFractional anisotropyWhite matter fractional anisotropyWhite matter FAGray matter maturationWhite matter differencesEffects of adversityLower white matter fractional anisotropyLowest values of FACourse of childhoodExperience-dependent mannerInterpersonal adversityGray matter regionsReceptive languageCognitive effectsDevelopmental theoryEarly environmentCognitive outcomesCognitive developmentNeighborhood adversityChildhood environmentCross-sectional associationsMatter regionsAdversity
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