2023
Widespread, depth‐dependent cortical microstructure alterations in pediatric focal epilepsy
Casella C, Vecchiato K, Cromb D, Guo Y, Winkler A, Hughes E, Dillon L, Green E, Colford K, Egloff A, Siddiqui A, Price A, Grande L, Wood T, Malik S, Teixeira R, Carmichael D, O'Muircheartaigh J. Widespread, depth‐dependent cortical microstructure alterations in pediatric focal epilepsy. Epilepsia 2023, 65: 739-752. PMID: 38088235, PMCID: PMC7616339, DOI: 10.1111/epi.17861.Peer-Reviewed Original ResearchDrug-resistant focal epilepsyFocal epilepsyMagnetic resonance imagingTreatment-related side effectsMRI-positive patientsMRI-negative patientsDisease severity measuresWidespread cortical areasPediatric focal epilepsyQuantitative magnetic resonance imagingPeriod of onsetTissue microstructural changesRadiological abnormalitiesUnderlying pathophysiologyHealthy controlsIndividual patientsCortical areasDisease processSide effectsPatientsFocal pathologyEpilepsyNeurobiological alterationsDisease severityResonance imaging
2018
Subfield-specific tractography of the hippocampus in epilepsy patients at 7 Tesla
Rutland J, Feldman R, Delman B, Panov F, Fields M, Marcuse L, Hof P, Lin H, Balchandani P. Subfield-specific tractography of the hippocampus in epilepsy patients at 7 Tesla. Seizure 2018, 62: 3-10. PMID: 30245458, PMCID: PMC6221989, DOI: 10.1016/j.seizure.2018.09.005.Peer-Reviewed Original ResearchConceptsMRI-negative patientsHealthy volunteersEpilepsy patientsMRI-negative epilepsy patientsHippocampal subfieldsDiffusion magnetic resonance imagingDetect subtle abnormalitiesTemporal seizure focusMagnetic resonance imagingAdvanced imaging techniquesSurgical treatmentPatients suspectedSurgical interventionAbnormal connectionSeizure focusPatientsResonance imagingFiber densityHippocampalEpilepsySeizuresImaging techniquesStructural imagingVolunteersProbabilistic tractography
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