Multivariate links between the developmental timing of adversity exposure and white matter tract connectivity in adulthood
Sisk L, Keding T, Cohodes E, McCauley S, Pierre J, Odriozola P, Kribakaran S, Haberman J, Zacharek S, Hodges H, Caballero C, Gold G, Huang A, Talton A, Gee D. Multivariate links between the developmental timing of adversity exposure and white matter tract connectivity in adulthood. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2025 PMID: 39978462, DOI: 10.1016/j.bpsc.2025.02.003.Peer-Reviewed Original ResearchWhite matter tractsAdverse exposuresPreschool-ageMiddle childhoodMental health in adulthoodDevelopment of white matter tractsEarly-life adversitySymptoms in adulthoodChildhood adversity exposureDevelopmental timing of exposureMental health problemsTiming of adversity exposureMental health burdenCortico-cortical communicationIncreased mental health burdenTract connectivityNeurobiological changesHealth in adulthoodModes of covariationSensorimotor functionMultivariate linksMental healthAdversityAdulthoodHealth burden
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