2024
Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study
Song W, Zhong W, Gao J, Li Z, Ren J, Shen D, Wang X, Shen Q, You F, Fu Q, Li C, Chen H, Lv Y, Shi X, Mao C. Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study. International Journal Of Obesity 2024, 48: 1438-1446. PMID: 38926462, DOI: 10.1038/s41366-024-01571-x.Peer-Reviewed Original ResearchMetabolically unhealthy non-obeseMetabolically healthy non-obeseMetabolically Healthy ObesityMetabolic obesity phenotypesOldest-old populationMetabolically unhealthy obesityProspective cohort studyMortality riskCohort studyHazard ratioObese phenotypeManagement of metabolic healthUnhealthy non-obeseOldest-old adultsHealthy non-obeseMethodsThis prospective cohort studyDecreased mortality riskIncreased mortality riskHigher mortality riskYears of follow-upAll-Cause MortalityNon-obeseEffect of obesityHealthy obesityCentral obesityCardiometabolic characteristics of people with metabolically healthy and unhealthy obesity
Petersen M, Smith G, Palacios H, Farabi S, Yoshino M, Yoshino J, Cho K, Davila-Roman V, Shankaran M, Barve R, Yu J, Stern J, Patterson B, Hellerstein M, Shulman G, Patti G, Klein S. Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity. Cell Metabolism 2024, 36: 745-761.e5. PMID: 38569471, PMCID: PMC11025492, DOI: 10.1016/j.cmet.2024.03.002.Peer-Reviewed Original ResearchConceptsUnhealthy obesityPlasma PAI-1 concentrationAbnormalities associated with obesityMetabolically Healthy ObesityMetabolically unhealthy obesityPAI-1 concentrationsMetabolic heterogeneity of obesityHeterogeneity of obesityMetabolically healthy leanSystemic metabolic functionCharacteristics of peopleDecreased oxidative stressHealthy obesityCardiometabolic characteristicsAdipose tissue biologyHealthy leanSkeletal muscle biologyPlasma adiponectinPlasma glucoseObesityMetabolic heterogeneityOxidative stressPotential mechanismsTissue biologyMuscle biology
2023
Exploring metabolically healthy obesity: prevalence, characteristics, and cardiovascular risk in the Iranian population based on the STEPS 2021
Langroudi A, Farzi Y, Masinaei M, Varniab Z, Shahin S, Rashidi M, Moghaddam S, Rahimi S, Khalili M, Keykhaei M, Ahmadi N, Kazemi A, Ghasemi E, Azadnajafabad S, Yoosefi M, Fattahi N, Nasserinejad M, Rezaei N, Haghshenas R, Dilmaghani-Marand A, Abdolhamidi E, Djalalinia S, Rezaei N, Larijani B, Farzadfar F. Exploring metabolically healthy obesity: prevalence, characteristics, and cardiovascular risk in the Iranian population based on the STEPS 2021. Journal Of Diabetes & Metabolic Disorders 2023, 23: 881-893. PMID: 38932890, PMCID: PMC11196437, DOI: 10.1007/s40200-023-01364-5.Peer-Reviewed Original ResearchPrevalence of metabolically healthy obesityMetabolically Healthy ObesityMetabolically unhealthy obesityHealthy obesityIranian populationCardiovascular diseaseOdds ratioMetabolically Healthy Obese IndividualsMetabolically healthy obese phenotypeMetabolically healthy obese groupPrevalence of obesityIncreasing prevalence of obesityCrude odds ratioCardiovascular disease riskRisk of cardiovascular diseaseCardiovascular riskHigh-risk individualsMetabolic syndrome criteriaAHA-NHLBIPublic health concernSubgroups of obesityUnhealthy obesityResultsThe prevalenceFramingham scoreMUO individuals
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