2013
Monitoring plaque inflammation in atherosclerotic rabbits with an iron oxide (P904) and 18F-FDG using a combined PET/MR scanner
Millon A, Dickson S, Klink A, Izquierdo-Garcia D, Bini J, Lancelot E, Ballet S, Robert P, de Castro J, Corot C, Fayad Z. Monitoring plaque inflammation in atherosclerotic rabbits with an iron oxide (P904) and 18F-FDG using a combined PET/MR scanner. Atherosclerosis 2013, 228: 339-345. PMID: 23582588, PMCID: PMC4128694, DOI: 10.1016/j.atherosclerosis.2013.03.019.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAorta, AbdominalAortic DiseasesAtherosclerosisAtorvastatinContrast MediaDextransDisease Models, AnimalDisease ProgressionFluorodeoxyglucose F18Heptanoic AcidsHydroxymethylglutaryl-CoA Reductase InhibitorsInflammationMagnetic Resonance ImagingMagnetite NanoparticlesPlaque, AtheroscleroticPositron-Emission TomographyPredictive Value of TestsPyrrolesRabbitsRadiographyRadiopharmaceuticalsTime FactorsConceptsFDG-PETPlaque inflammationRegression groupAbdominal aortaAtherosclerotic rabbitsAortic wallMean standard uptake valueStrong FDG uptakeStandard uptake valueContrast-enhanced MRIFDG-PET dataFunctional imaging modalitiesProgression groupBaseline imagingFDG uptakeMR scannerSUVmean valuesUSPIO uptakeAtherosclerotic plaquesMacrophage densityUptake valueEarly changesInflammationRabbit modelDietary changes
1992
Spectroscopic imaging of stroke in humans: histopathology correlates of spectral changes.
Petroff O, Graham G, Blamire A, Al-Rayess M, Rothman D, Fayad P, Brass L, Shulman R, Prichard J. Spectroscopic imaging of stroke in humans: histopathology correlates of spectral changes. Neurology 1992, 42: 1349-54. PMID: 1620345, DOI: 10.1212/wnl.42.7.1349.Peer-Reviewed Original ResearchConceptsCells/mm2Foamy macrophagesElevation of lactateGlial densityNeuropathologic examinationBrain macrophagesHuman strokeHistopathology correlateMacrophage densityInfarctsHigh lactateHistopathologic sectionsStrokeLactate concentrationMedial marginMacrophagesLactate signalMonthsLactate poolWeeksLactateCellular localizationMetabolic turnoverMagnetic resonanceMagnetic resonance spectroscopy
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