2012
In vivo imaging of virological synapses
Sewald X, Gonzalez DG, Haberman AM, Mothes W. In vivo imaging of virological synapses. Nature Communications 2012, 3: 1320. PMID: 23271654, PMCID: PMC3784984, DOI: 10.1038/ncomms2338.Peer-Reviewed Original ResearchConceptsVirological synapsesHuman T-cell lymphotropic virusMurine leukemia virusHuman immunodeficiency virusLeukemia virusViral envelope glycoproteinsLymph nodesImmunodeficiency virusFriend murine leukemia virusLymphotropic virusB cellsIntravital microscopyCell-cell contactEnvelope glycoproteinSynapsesUninfected cellsIntravital imagingVirusMiceVivoCellsLeucocytes
2003
Spread of HTLV-I Between Lymphocytes by Virus-Induced Polarization of the Cytoskeleton
Igakura T, Stinchcombe J, Goon P, Taylor G, Weber J, Griffiths G, Tanaka Y, Osame M, Bangham C. Spread of HTLV-I Between Lymphocytes by Virus-Induced Polarization of the Cytoskeleton. Science 2003, 299: 1713-1716. PMID: 12589003, DOI: 10.1126/science.1080115.Peer-Reviewed Original ResearchMeSH KeywordsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell Adhesion MoleculesCell CommunicationCell LineCell PolarityExtracellular SpaceGene Products, envGene Products, gagGenome, ViralHTLV-I InfectionsHuman T-lymphotropic virus 1HumansIn Situ Hybridization, FluorescenceIntercellular JunctionsMicroscopy, ConfocalMicrotubule-Organizing CenterMicrotubulesNucleocapsid ProteinsPeptide Nucleic AcidsReceptors, Antigen, T-CellT-LymphocytesTalinVirion
2000
Fratricide among CD8+ T Lymphocytes Naturally Infected with Human T Cell Lymphotropic Virus Type I
Hanon E, Stinchcombe J, Saito M, Asquith B, Taylor G, Tanaka Y, Weber J, Griffiths G, Bangham C. Fratricide among CD8+ T Lymphocytes Naturally Infected with Human T Cell Lymphotropic Virus Type I. Immunity 2000, 13: 657-664. PMID: 11114378, DOI: 10.1016/s1074-7613(00)00065-0.Peer-Reviewed Original ResearchConceptsCD8(+) T lymphocytesT lymphocytesHTLV-ICD8+ T lymphocytesHuman T-lymphotropic virus type ICD4(+) T lymphocytesEpstein-Barr virus-specificHuman T-cell lymphotropic virus type IHTLV-I-specificVirus-specific CTLHTLV-I infectionType IImmune controlLymphotropic virusHTLV-I.Virus-specificProtein expressionIn vivoInfectionGene expressionCD8ExpressionFratricideGenetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages
Jesus M, Anders C, Miller G, Sleasman J, Goodenow M, Andiman W. Genetically and epidemiologically related “non‐syncytium‐inducing” isolates of HIV‐1 display heterogeneous growth patterns in macrophages. Journal Of Medical Virology 2000, 61: 171-180. PMID: 10797371, DOI: 10.1002/(sici)1096-9071(200006)61:2<171::aid-jmv1>3.0.co;2-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmino Acid SequenceAntigens, ViralCD4 AntigensCell LineCells, CulturedChild, PreschoolFemaleGiant CellsHIV Core Protein p24HIV InfectionsHIV-1HumansInfantLeukocytes, MononuclearMacrophagesMolecular Sequence DataPhenotypeProspective StudiesProtein Structure, TertiaryReceptors, ChemokineTransfectionTropismU937 CellsViral ProteinsVirus ReplicationConceptsNSI virusesDisease stageSurrogate markerPediatric human immunodeficiency virus type 1 (HIV-1) infectionHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionCell linesCo-receptor preferenceM-tropic virusesType 1 infectionT-cell tropicDual tropicInducing (NSI) virusesNSI isolatesAsymptomatic childrenMacrophage-tropicClinical progressionSymptomatic childrenV3 loopNSI phenotypeHIV-1Lymphotropic virusCategory A1Heterogeneous growth patternsGenetic features
1999
Direct analysis of viral-specific CD8+ T cells with soluble HLA-A2/Tax11-19 tetramer complexes in patients with human T cell lymphotropic virus-associated myelopathy.
Bieganowska K, Höllsberg P, Buckle G, Lim D, Greten T, Schneck J, Altman J, Jacobson S, Ledis S, Hanchard B, Chin J, Morgan O, Roth P, Hafler D. Direct analysis of viral-specific CD8+ T cells with soluble HLA-A2/Tax11-19 tetramer complexes in patients with human T cell lymphotropic virus-associated myelopathy. The Journal Of Immunology 1999, 162: 1765-71. PMID: 9973440, DOI: 10.4049/jimmunol.162.3.1765.Peer-Reviewed Original ResearchMeSH KeywordsAdultB7-1 AntigenCD28 AntigensCD8-Positive T-LymphocytesFemaleGene Products, taxHLA-A2 AntigenHuman T-lymphotropic virus 1HumansLymphocyte ActivationMaleMiddle AgedParaparesis, Tropical SpasticPeptide FragmentsPhenotypeProtein ConformationReceptors, Antigen, T-Cell, alpha-betaReceptors, ChemokineReceptors, Interleukin-2SolubilityConceptsT cellsIL-2RMHC class I tetramersHuman T-cell lymphotropic virusViral-specific CD8Class I tetramersProgressive neurologic diseaseDifferent chemokine receptorsHLA-A2 alleleCentral nervous systemTCR Vbeta chainsReactive CD8TCR usageInflammatory infiltrateVbeta chainsChemokine receptorsNeurologic diseaseImmune responseCD8Lymphotropic virusMyelopathyNervous systemPatientsHTLVClonal expansion
1996
Viral infections in short-term injection drug users: the prevalence of the hepatitis C, hepatitis B, human immunodeficiency, and human T-lymphotropic viruses.
Garfein R, Vlahov D, Galai N, Doherty M, Nelson K. Viral infections in short-term injection drug users: the prevalence of the hepatitis C, hepatitis B, human immunodeficiency, and human T-lymphotropic viruses. American Journal Of Public Health 1996, 86: 655-661. PMID: 8629715, PMCID: PMC1380472, DOI: 10.2105/ajph.86.5.655.Peer-Reviewed Original ResearchConceptsHepatitis B virusHepatitis C virusViral infectionSeroprevalence of HCVBlood-borne viral infectionsHuman T-lymphotropic virus type IShort-term injectorsHuman immunodeficiency virusSexual risk reduction interventionInjection drug usersIllicit drug injectorsRisk reduction interventionsVirus type IHepatitis CHepatitis BHIV infectionImmunodeficiency virusPrimary preventionC virusB virusHuman immunodeficiencyDrug injectionSequential cohortsDrug injectorsLymphotropic virus
1992
Comparison of enzyme-linked immunosorbent and indirect immunofluorescence assays for the detection of human T-cell lymphotropic virus type-I antibodies in sera from rural Haiti
Grant W, Bia F, Chacko T, Jean-Baptiste M, Griffith B. Comparison of enzyme-linked immunosorbent and indirect immunofluorescence assays for the detection of human T-cell lymphotropic virus type-I antibodies in sera from rural Haiti. Diagnostic Microbiology And Infectious Disease 1992, 15: 121-124. PMID: 1572136, DOI: 10.1016/0732-8893(92)90034-q.Peer-Reviewed Original ResearchConceptsWestern blotHuman T-cell lymphotropic virus type IHuman T-cell lymphotropic virusEnzyme immunoassayRural HaitiLymphotropic virus type IRural Haitian populationUninfected H9 cellsPrevalence of HTLVMT-2 cellsPositive samplesEnzyme-linked immunosorbentVirus type IAvailable enzyme immunoassayIndirect immunofluorescence assaysNeurologic diseaseLymphotropic virusH9 cellsHealthy individualsIndirect immunofluorescenceImmunofluorescence assaysSerum samplesHaitian populationSerumHTLV
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