Acute ischemic stroke on anti-Xa inhibitors: Pharmacokinetics and outcomes
Basso C, Goldstein E, Dai X, Rana M, Shu L, Chen C, Sweeney J, Stretz C, Smith EE, Gurol ME, de Havenon A, Burton T, Fussell-Louie D, Furie K, Yaghi S. Acute ischemic stroke on anti-Xa inhibitors: Pharmacokinetics and outcomes. Journal Of Stroke And Cerebrovascular Diseases 2022, 31: 106612. PMID: 35863261, DOI: 10.1016/j.jstrokecerebrovasdis.2022.106612.Peer-Reviewed Original ResearchConceptsDOAC useAcute ischemic stroke patientsSingle-center retrospective studyAnti-Xa inhibitorsAnti-Xa levelsCenter retrospective studyAcute ischemic strokeIschemic stroke patientsEfficacy of thrombolysisRisk of mortalityDOAC therapyXa levelsIschemic strokeConsecutive patientsSuch patientsStroke patientsThrombolytic therapyAtrial fibrillationRetrospective studyPharmacokinetic correlatesDrug levelsPatientsThrombolysisDOACIngestion
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