T lymphocytes and cytotoxic astrocyte blebs correlate across autism brains
DiStasio MM, Nagakura I, Nadler MJ, Anderson MP. T lymphocytes and cytotoxic astrocyte blebs correlate across autism brains. Annals Of Neurology 2019, 86: 885-898. PMID: 31591744, PMCID: PMC7210715, DOI: 10.1002/ana.25610.Peer-Reviewed Original ResearchConceptsInnate immune responseT lymphocytesImmune responseASD brainCell-mediated injuryAutism spectrum disorderAdaptive immune cellsCSF-brain barrierMost brain regionsWhite matter vesselsPostmortem brain tissueRare genetic causeAnn NeurolLymphocytic cuffsLymphocyte numbersPathologic featuresCerebral cortexInflammatory cytokinesBrain barrierImmune cellsPostmortem brainsCerebrospinal fluidB lymphocytesEpendymal surfacePerivascular spaces
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