2025
Updates in Pregnancy in Individuals with Obesity and After Bariatric Surgery
Espinal M, Hairston J, Kominiarek M. Updates in Pregnancy in Individuals with Obesity and After Bariatric Surgery. Obstetrics And Gynecology Clinics Of North America 2025, 52: 413-430. PMID: 40769654, DOI: 10.1016/j.ogc.2025.05.001.Peer-Reviewed Original ResearchConceptsGestational diabetesBariatric surgeryRisk of gestational diabetesAnti-obesity medicationsEarly pregnancy lossCesarean deliveryPostpartum hemorrhagePreterm birthDelivery complicationsSurgical complicationsSurgical infectionsCongenital anomaliesPregnancy lossPregnancy planningPregnancyNutritional deficienciesSurgeryLong-term effectsObesityReproductive healthComplicationsDiabetesAnti-obesitySafety concernsRisk
2024
Considerations for the design and conduct of pediatric obesity pharmacotherapy clinical trials: Proceedings of expert roundtable meetings
Kelly A, Bahlke M, Baker J, de Beaufort C, Belin R, Fonseca H, Hale P, Holm J, Hsia D, Jastreboff A, Juliusson P, Murphy M, Pak J, Paul E, Rudolph B, Srivastava G, Tornøe C, Weghuber D, Fox C. Considerations for the design and conduct of pediatric obesity pharmacotherapy clinical trials: Proceedings of expert roundtable meetings. Pediatric Obesity 2024, 19: e13161. PMID: 39289849, DOI: 10.1111/ijpo.13161.Peer-Reviewed Original ResearchAnti-obesity medicationsExcessive weight reductionClinical trialsEnd pointsDown-titrationEligibility criteriaLong-term health outcomesBMI z-scoreActive comparatorEfficacy end pointPlacebo-controlled trialSecondary end pointsRun-in phaseFollow-up periodFollow-up phaseHealth outcomesObesity expertsTrial eligibility criteriaClinical careWeight reductionMultidisciplinary groupClinical trial protocolsPrimary outcomeWeight regainTrial protocol
2023
Expanding the Use of Medications for Alcohol Use Disorder: Lessons from the Proliferation of Anti-obesity Medications
Bernstein E, Moreno J, Edelman E. Expanding the Use of Medications for Alcohol Use Disorder: Lessons from the Proliferation of Anti-obesity Medications. Journal Of General Internal Medicine 2023, 39: 1233-1235. PMID: 38087177, PMCID: PMC11116289, DOI: 10.1007/s11606-023-08565-x.Peer-Reviewed Original Research
2019
Adjuvant Pharmaceutical Therapy for Perioperative Use in Bariatric Surgery
Morton J, Ghiassi S, Nadzam G. Adjuvant Pharmaceutical Therapy for Perioperative Use in Bariatric Surgery. 2019, 619-624. DOI: 10.1007/978-3-030-27021-6_56.Peer-Reviewed Original Research
2016
[PP.13.07] HYPERTENSION AND CARDIOVASCULAR DISEASE RISK REDUCTION IN OBESE PATIENTS WITH BINGE EATING DISORDER
Grilo C. [PP.13.07] HYPERTENSION AND CARDIOVASCULAR DISEASE RISK REDUCTION IN OBESE PATIENTS WITH BINGE EATING DISORDER. Journal Of Hypertension 2016, 34: e192-e193. DOI: 10.1097/01.hjh.0000491879.94394.fc.Peer-Reviewed Original ResearchBinge-eating disorderAnti-obesity medicationsCVD risk factorsObese patientsBlood pressureMetabolic syndromeCardiovascular disease risk reductionStepped-care treatmentSubgroup of patientsDisease risk reductionMental Health SurveyObese BED patientsBinge Eating DisorderCognitive behavioral therapyOverall significant decreaseMedical comorbiditiesRemission rateRisk factorsInitial respondersHealth SurveyHeart rateBED patientsHypertensionMixed model analysisPatientsRandomized controlled trial testing behavioral weight loss versus multi-modal stepped-care treatment for binge eating disorder
Grilo C. Randomized controlled trial testing behavioral weight loss versus multi-modal stepped-care treatment for binge eating disorder. European Psychiatry 2016, 33: s163. DOI: 10.1016/j.eurpsy.2016.01.321.Peer-Reviewed Original ResearchStepped-care treatmentAnti-obesity medicationsRemission rateWeight lossBehavioral weight lossCo-morbid obesityStepped-care modelObese BED patientsSignificant time effectInitial respondersTreatment challengesBED patientsMedicationsMixed model analysisPatientsBingePlaceboMonthsObesityBWLTreatmentStructured interviewsCBTDisordersMixed models
2014
Treatment of binge eating disorder in racially and ethnically diverse obese patients in primary care: Randomized placebo-controlled clinical trial of self-help and medication
Grilo CM, Masheb RM, White MA, Gueorguieva R, Barnes RD, Walsh BT, McKenzie KC, Genao I, Garcia R. Treatment of binge eating disorder in racially and ethnically diverse obese patients in primary care: Randomized placebo-controlled clinical trial of self-help and medication. Behaviour Research And Therapy 2014, 58: 1-9. PMID: 24857821, PMCID: PMC4074556, DOI: 10.1016/j.brat.2014.04.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAnti-Obesity AgentsBinge-Eating DisorderBlack or African AmericanBody WeightCognitive Behavioral TherapyCombined Modality TherapyCyclobutanesDouble-Blind MethodFemaleHispanic or LatinoHumansMaleMiddle AgedObesityPrimary Health CareSelf CareTime FactorsTreatment OutcomeWhite PeopleYoung AdultConceptsSelf-help cognitive behavioral therapyDiverse obese patientsAnti-obesity medicationsObese patientsModerate clinical outcomePercent weight lossTime interaction effectsWeight lossClinical outcomesPrimary careRandomized placebo-controlled clinical trialSecond placebo-controlled trialPlacebo-controlled clinical trialAcute weight lossPlacebo-controlled trialDouble-blind fashionDiscontinuation of medicationPrimary care settingWeight loss maintenanceSpecialist treatment centresTreatment of bingeDiverse patient groupsSelf-help CBTBinge-eating frequencyDemographic factors
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