Generation of targeted Chlamydia trachomatis null mutants
Kari L, Goheen M, Randall L, Taylor L, Carlson J, Whitmire W, Virok D, Rajaram K, Endresz V, McClarty G, Nelson D, Caldwell H. Generation of targeted Chlamydia trachomatis null mutants. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: 7189-7193. PMID: 21482792, PMCID: PMC3084044, DOI: 10.1073/pnas.1102229108.Peer-Reviewed Original ResearchConceptsGenetic systemBacterial pathogensObligate intracellular bacterial pathogenReverse-genetics approachTryptophan synthase genesEthyl methanesulfonate mutagenesisIntracellular bacterial pathogensGenome sequenceNull mutantsPCR ampliconsSynthase geneAnti-microbial effectsTarget genesMutantsChlamydial pathogenesisParental clonesMutationsTryptophan starvationGenomeInfected hundredsGenesPathogensSEXUALLY TRANSMITTED DISEASESMutagenic organicsTarget region
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply