2023
Circulating Levels of Leptin and Lipocalin-2 in Patients With X-Linked Hypophosphatemia
Simpson C, Santoro A, Carpenter T, Deng Y, Parziale S, Insogna K. Circulating Levels of Leptin and Lipocalin-2 in Patients With X-Linked Hypophosphatemia. Journal Of The Endocrine Society 2023, 7: bvad116. PMID: 37860221, PMCID: PMC10583534, DOI: 10.1210/jendso/bvad116.Peer-Reviewed Original ResearchLipocalin-2Control subjectsGreater riskLevels of LCN2Excessive weight gainLevels of leptinSerum leptin levelsCirculating LevelsLCN2 levelsSerum levelsYear age cohortLeptin levelsMetabolic abnormalitiesRetrospective studyAge cohortsInsulin sensitivityHigh prevalencePatientsWeight gainXLHLeptinAge 2HypophosphatemiaObesityChildren
2021
Associations of perfluoroalkyl and polyfluoroalkyl substances (PFAS) and PFAS mixtures with adipokines in midlife women
Ding N, Karvonen-Gutierrez C, Herman W, Calafat A, Mukherjee B, Park S. Associations of perfluoroalkyl and polyfluoroalkyl substances (PFAS) and PFAS mixtures with adipokines in midlife women. International Journal Of Hygiene And Environmental Health 2021, 235: 113777. PMID: 34090141, PMCID: PMC8207532, DOI: 10.1016/j.ijheh.2021.113777.Peer-Reviewed Original ResearchConceptsBayesian kernel machine regressionNormal weightStudy of Women's HealthCirculating levels of leptinHMW adiponectinBayesian kernel machine regression analysisSoluble leptin receptorFree leptin indexSOB-R concentrationsBaseline serum samplesLevels of leptinMultivariate linear regressionPhysical activityAssociated with obesityStatistically significant associationWomen's healthPolyfluoroalkyl substancesWaist circumferenceKernel machine regressionWomen's backgroundInfluence obesityMidlife womenSmoking statusSOB-RMenopausal status
2010
Altered Metabolism and Lipodystrophy in the Early B-Cell Factor 1-Deficient Mouse
Fretz JA, Nelson T, Xi Y, Adams DJ, Rosen CJ, Horowitz MC. Altered Metabolism and Lipodystrophy in the Early B-Cell Factor 1-Deficient Mouse. Endocrinology 2010, 151: 1611-1621. PMID: 20172967, PMCID: PMC2850234, DOI: 10.1210/en.2009-0987.Peer-Reviewed Original ResearchMeSH KeywordsAdiponectinAdipose TissueAnimalsBlood GlucoseBone MarrowCalorimetryCCAAT-Enhancer-Binding Protein-betaEnergy MetabolismGlucagonInsulinLeptinLipid MetabolismLipodystrophyMiceMice, KnockoutPPAR gammaReverse Transcriptase Polymerase Chain ReactionRNA, MessengerStatistics, NonparametricTrans-ActivatorsConceptsSerum glucose levelsWhite adipose tissueMarrow adiposityGlucose levelsAdipose tissueLevels of leptinBone formation rateAdipose tissue depositionNumber of osteoblastsWk of ageAltered bone morphologySerum osteocalcinInsulin levelsGlucose challengeIP injectionPancreatic hormonesLittermate controlsLipid depositionBone marrowSerum analysisBrown adiposeTissue depositionAltered metabolismMiceAdiposity
1999
Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight*
Kalra S, Dube M, Pu S, Xu B, Horvath T, Kalra P. Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight*. Endocrine Reviews 1999, 20: 68-100. PMID: 10047974, DOI: 10.1210/edrv.20.1.0357.Peer-Reviewed Original ResearchConceptsOrexigenic signalsAppetite-regulating pathwaysInfluence of GABAHypothalamic regulation of body weightNeural timing mechanismNPY-induced feedingCirculating levels of leptinDevelopment of leptin resistanceRegulation of body weightManagement of energy homeostasisCirculating leptin levelsSCN of rodentsLevels of leptinTiming mechanismInterruption of neurotransmissionExpression of NPYNeural mechanismsLeptin gene expressionNeural eventsNeural sitesGene expressionDaily pattern of feedingIngestive behaviorPattern of feedingPostsynaptic level
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