2022
Performance Of The MELDXI Score In A Modern Left Ventricular Assist Device Cohort
Stawiarski K, Agboola O, Costantino A, Raskhe A, Bonde R, Bonde P. Performance Of The MELDXI Score In A Modern Left Ventricular Assist Device Cohort. Journal Of Cardiac Failure 2022, 28: s79-s80. DOI: 10.1016/j.cardfail.2022.03.201.Peer-Reviewed Original ResearchPost-operative adverse eventsMELD-XIAdverse eventsHigh riskCox proportional hazard ratiosLeft ventricular assist device placementRed blood cell transfusionVentricular assist device placementMELD-XI scorePerioperative transfusion requirementsPostoperative adverse eventsAdverse perioperative eventsBlood cell transfusionPost-operative bleedingProportional hazard ratiosDisease risk scoreKaplan-Meir plotsWilcoxon rank sum testLog-rank statisticsRank sum testDevice cohortLVAD candidatesTransfusion requirementsBaseline characteristicsCause mortality
2021
MELD score is predictive of 90-day mortality after veno-arterial extracorporeal membrane oxygenation support
Karnib M, Haraf R, Tashtish N, Zanath E, Elshazly T, Garcia R, Billings S, Fetros M, Bradigan A, Zacharias M, Abu-Omar Y, Elgudin Y, Pelletier M, Al-Kindi S, Lytle F, ElAmm C. MELD score is predictive of 90-day mortality after veno-arterial extracorporeal membrane oxygenation support. The International Journal Of Artificial Organs 2021, 45: 404-411. PMID: 34702105, DOI: 10.1177/03913988211054865.Peer-Reviewed Original ResearchConceptsMELD-Na scoreVA-ECMOMELD scoreMELD-XIReceiver Operating CharacteristicMELD-NaCardiogenic shockSingle-center retrospective reviewVeno-arterial extracorporeal membrane oxygenationExtracorporeal membrane oxygenation supportMultivariate Cox regression analysisVeno-arterial extracorporeal membrane oxygenation supportVA-ECMO initiationLeft ventricular assist device placementVentricular assist device placementMELD-XI scoreExtracorporeal membrane oxygenationMembrane oxygenation supportMarker of survivalCox regression analysisPredictive of survivalLong-term mortalityChronic liver diseaseAssociated with mortalityECMO initiationExploring Preoperative Hypocalcemia as a Biomarker for Post Left Ventricular Assist Device Survival and Adverse Events
Stawiarski K, Agboola O, Bonde R, Bonde P. Exploring Preoperative Hypocalcemia as a Biomarker for Post Left Ventricular Assist Device Survival and Adverse Events. The Journal Of Heart And Lung Transplantation 2021, 40: s430. DOI: 10.1016/j.healun.2021.01.1200.Peer-Reviewed Original ResearchAdverse eventsHypocalcemia groupPreoperative hypocalcemiaCause mortalityRight ventricular assist device useLeft ventricular assist device placementChronic heart failure patientsVentricular assist device placementVentricular assist device useDurable LVAD implantationPerioperative renal failureChronic kidney diseaseHeart failure patientsMajority of patientsSerum calcium levelsPoor prognostic markerAbnormal calcium handlingKaplan-Meir plotsLog-rank statisticsCox modellingLVAD implantationLVAD placementPreoperative levelsProlonged intubationRenal failure
2020
Blood Conservation Strategy at Time of Left Ventricular Assist Device Placement Improves Survival
Stawiarski K, Agboola O, Park J, Mangi A, Geirsson A, Lee F, Jacoby D, Bellumkonda L, Ahmad T, Chou J, Testani J, Chen M, McCloskey G, Bonde P. Blood Conservation Strategy at Time of Left Ventricular Assist Device Placement Improves Survival. The Journal Of Heart And Lung Transplantation 2020, 39: s151. DOI: 10.1016/j.healun.2020.01.1086.Peer-Reviewed Original ResearchVentricular assist device placementBlood conservationLeft ventricular assist device placementBCS groupDevice placementAnti-platelet useLarger ventricular sizeLiberal transfusion strategyStandardized transfusion protocolTime of LVADLength of hospitalBlood conservation strategiesUnits of PRBCsLiberal groupCirculatory support devicesDevice use ratesExcessive transfusionICU stayTransfusion protocolCommon complicationHeart failureLVAD patientsTransfusion strategyTransfusion triggerSingle center
2018
Comparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement
Abubakar H, Subahi A, Adegbala O, Yassin A, Akintoye E, Abdulrahman A, Ahmed A, Alade A, Pahuja M, Afonso L. Comparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement. The American Journal Of Cardiology 2018, 123: 414-418. PMID: 30545482, DOI: 10.1016/j.amjcard.2018.10.039.Peer-Reviewed Original ResearchConceptsVentricular assist device placementPostoperative myocardial infarctionLength of stayHospital mortalityVascular complicationsLVAD placementMyocardial infarctionEnd pointLeft ventricular assist device placementNationwide Inpatient Sample databaseST-segment myocardial infarctionDevice placementPeriprocedural vascular complicationsHeart failure etiologyIn-Hospital OutcomesPrimary end pointSecondary end pointsClinical end pointsHospital-level characteristicsCost of hospitalizationHemorrhage requiring transfusionMixed-effects logistic modelHospital outcomesFailure etiologyIschemic cardiomyopathy
2016
Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support
Ahmad T, Kelly JP, McGarrah RW, Hellkamp AS, Fiuzat M, Testani JM, Wang TS, Verma A, Samsky MD, Donahue MP, Ilkayeva OR, Bowles DE, Patel CB, Milano CA, Rogers JG, Felker GM, O’Connor C, Shah SH, Kraus WE. Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support. Journal Of The American College Of Cardiology 2016, 67: 291-299. PMID: 26796394, PMCID: PMC5429585, DOI: 10.1016/j.jacc.2015.10.079.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarnitineDisease ProgressionEnergy MetabolismExercise TherapyFemaleHeart Failure, SystolicHeart-Assist DevicesHospital MortalityHumansMaleMass SpectrometryMiddle AgedNorth CarolinaOutcome Assessment, Health CarePrognosisReproducibility of ResultsSeverity of Illness IndexStatistics as TopicConceptsEnd-stage heart failureSystolic heart failureHeart failureMechanical circulatory supportHF patientsClinical outcomesCirculatory supportEnd-stage systolic heart failureChronic systolic HF patientsLeft ventricular assist device placementLong-term mechanical circulatory supportVentricular assist device placementPeak VO2 levelsChronic HF patientsSystolic HF patientsAdverse clinical outcomesClinical trial outcomesLong-chain acylcarnitinesAssociations of metabolitesFrozen plasma samplesMechanical circulatoryCardiovascular deathCause hospitalizationCause mortalityLVAD group
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