2015
Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis
Overton JD, Komiya Y, Mezzacappa C, Nama K, Cai N, Lou L, Fedeles SV, Habas R, Runnels LW. Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis. Scientific Reports 2015, 5: 18395. PMID: 26671672, PMCID: PMC4680877, DOI: 10.1038/srep18395.Peer-Reviewed Original ResearchConceptsXenopus laevis embryosEmbryonic lethalityTRPM7 functionLaevis embryosProtein kinase C substrate 80KEarly embryonic lethalityNoncatalytic beta subunitXenopus laevis embryogenesisEmbryonic day E11.5TRPM7 ion channelVertebrate gastrulationGastrulation defectsResident enzymesEarly embryogenesisPolycystin-2TRPM7 protein expressionDay E11.5KDa proteinGlucosidase IIEndoplasmic reticulumBeta subunitOverexpression of TRPM7Second alleleSomatic lossIon channels
2014
Synucleins☆
Vargas K, Chandra S. Synucleins☆. 2014 DOI: 10.1016/b978-0-12-801238-3.04785-1.Peer-Reviewed Original ResearchVertebrate-specific gene familyHuman α-synuclein geneSynaptic vesicle cyclingGene familyNormal physiological functionFamilial Parkinson's diseaseVesicle cyclingΑ-synucleinKDa proteinPhysiological functionsΒ-synucleinΑ-synuclein geneNeurodegenerative disordersProteinΓ-synucleinPresynaptic terminalsSynuclein
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